Data from: NMDA receptor antagonists and pain relief: a meta-analysis of experimental trials

  • Trevor Thompson (Creator)
  • Fiona Catherine Wood Whiter (Creator)
  • Katy Gallop (Creator)
  • Nicola Veronese (Creator)
  • Marco Solmi (Creator)
  • P Newton (Creator)
  • Brendon Stubbs (Creator)

Dataset

Description

OBJECTIVES: We conducted a meta-analysis of controlled trials that used experimental models of acute pain and hyperalgesia to examine the analgesic effects of N-methyl-D-aspartate receptor (NMDAR) antagonists. METHODS: Six major databases were systematically searched (to 03/2018) for studies using human evoked pain models to compare NMDAR antagonists with no-intervention controls. Pain outcome data were analyzed with random-effects meta-analysis. RESULTS: Searches identified 70 eligible trials (N=1069). Meta-analysis found that low-dose ketamine

External deposit with Dryad.
Date made available15 Mar 2019
PublisherDryad

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