The York Research Database

Global analysis of protein N-myristoylation and exploration of N-myristoyltransferase as a drug target in the neglected human pathogen Leishmania donovani

Wright, M. H., Paape, D., Storck, E. M., Serwa, R. A., Smith, D. F. & Tate, E. W., 19 Mar 2015

Article in Chemistry & Biology

Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes

Altun, M., Kramer, H. B., Willems, L. I., McDermott, J. L., Leach, C. A., Goldenberg, S. J., Kumar, K. G. S., Konietzny, R., Fischer, R., Kogan, E., MacKeen, M. M., McGouran, J., Khoronenkova, S. V., Parsons, J. L., Dianov, G. L., Nicholson, B. & Kessler, B. M., 23 Nov 2011

Article in Chemistry & Biology

Elevation of Global O-GlcNAc in Rodents Using a Selective O-GlcNAcase Inhibitor Does Not Cause Insulin Resistance or Perturb Glucohomeostasis

Macauley, M. S., Shan, X., Yuzwa, S. A., Gloster, T. M. & Vocadlo, D. J., 24 Sep 2010

Article in Chemistry & Biology

Inhibition of O-GlcNAcase Using a Potent and Cell-Permeable Inhibitor Does Not Induce Insulin Resistance in 3T3-L1 Adipocytes

Macauley, M. S., He, Y., Gloster, T. M., Stubbs, K. A., Davies, G. J. & Vocadlo, D. J., 24 Sep 2010

Article in Chemistry & Biology

Divergence of Catalytic Mechanism within a Glycosidase Family Provides Insight into Evolution of Carbohydrate Metabolism by Human Gut Flora

Gloster, T. M., Turkenburg, J. P., Potts, J. R., Henrissat, B. & Davies, G. J., 20 Oct 2008

Article in Chemistry & Biology

Insights into the synthesis of lipopolysaccharide and antibiotics through the structures of two retaining glycosyltransferases from family GT4

Martinez-Fleites, C., Proctor, M., Roberts, S., Bolam, D. N., Gilbert, H. J. & Davies, G. J., Nov 2006

Article in Chemistry & Biology

Low pH changes the profile of nodulation factors produced by Rhizobium tropici CIAT899

Moron, B., Soria-Diaz, M. E., Ault, J., Verroios, G., Noreen, S., Rodriguez-Navarro, D. N., Gil-Serrano, A., Thomas-Oates, J., Megias, M. & Sousa, C., Sep 2005

Article in Chemistry & Biology

Structure-activity relationships in purine-based inhibitor binding to HSP90 isoforms

Wright, L., Barril, X., Dymock, B., Sheridan, L., Surgenor, A., Beswick, M., Drysdale, M., Collier, A., Massey, A., Davies, N., Fink, A., Fromont, C., Aherne, W., Boxall, K., Sharp, S., Workman, P. & Hubbard, R. E., Jun 2004

Article in Chemistry & Biology

Anatomy of glycosynthesis: Structure and kinetics of the Humicola insolens Cel7B E197A and E197S glycosynthase mutants

Ducros, V. M. A., Tarling, C. A., Zechel, D. L., Brzozowski, A. M., Frandsen, T. P., von Ossowski, I., Schulein, M., Withers, S. G. & Davies, G. J., Jul 2003

Article in Chemistry & Biology

Insights into trehalose synthesis provided by the structure of the retaining glucosyltransferase OtsA

Gibson, R. P., Turkenburg, J. P., Charnock, S. J., Lloyd, R. & Davies, G. J., Dec 2002

Article in Chemistry & Biology

Catalysis and specificity in enzymatic glycoside hydrolysis: a B-2,B-5 conformation for the glycosyl-enzyme intermediate revealed by the structure of the Bacillus agaradhaerens family 11 xylanase

Sabini, E., Sulzenbacher, G., Dauter, M., Dauter, Z., Jorgensen, P. L., Schulein, M., Dupont, C., Davies, G. J. & Wilson, K. S., Jul 1999

Article in Chemistry & Biology

Accommodating structurally diverse peptides in proteins

Wilkinson, A. J., Jul 1996

Article in Chemistry & Biology