JOURNAL OF MEDICINAL CHEMISTRY

ISSNs: 0022-2623

American Chemical Society

Scopus rating (2018): CiteScore 6.23 SJR 2.287 SNIP 1.676

Journal

Publications

  1. 2018
  2. Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

    Waszkowycz, B., Smith, K. M., McGonagle, A. E., Jordan, A. M., Acton, B., Fairweather, E. E., Griffiths, L. A., Hamilton, N. M., Hamilton, N. S., Hitchin, J. R., Hutton, C. P., James, D. I., Jones, C. D., Jones, S., Mould, D. P., Small, H. F., Stowell, A. I. J., Tucker, J. A., Waddell, I. D. & Ogilvie, D. J., 13 Dec 2018

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  3. 2017
  4. Insulin-like Growth Factor 1 Analogs Clicked in the C Domain: Chemical Synthesis and Biological Activities

    Macháčková, K., Collinsová, M., Chrudinová, M., Selicharová, I., Pícha, J., Buděšínský, M., Vaněk, V., Žáková, L., Brzozowski, A. M. & Jiráček, J., 28 Dec 2017

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  5. Design of Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitors Using a Crystallographic Surrogate Derived from Checkpoint Kinase 1 (CHK1)

    Williamson, D. S., Smith, G. P., Acheson-Dossang, P., Bedford, S. T., Chell, V., Chen, I-J., Daechsel, J. C. A., Daniels, Z., David, L., Dokurno, P., Hentzer, M., Herzig, M. C., Hubbard, R. E., Moore, J. D., Murray, J. B., Newland, S., Ray, S. C., Shaw, T., Surgenor, A. E., Terry, L. & 3 others, Thirstrup, K., Wang, Y. & Christensen, K. V., 12 Oct 2017

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  6. 2014
  7. Structure-based design of potent and selective leishmania N-myristoyltransferase inhibitors

    Hutton, J. A., Goncalves, V., Brannigan, J. A., Paape, D., Wright, M. H., Waugh, T. M., Roberts, S. M., Bell, A. S., Wilkinson, A. J., Smith, D. F., Leatherbarrow, R. J. & Tate, E. W., 19 Sep 2014

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  8. 2013
  9. 2012
  10. Synthesis and evaluation of α-thymidine analogues as novel antimalarials

    Cui, H., Carrero-Lérida, J., Silva, A. P. G., Whittingham, J. L., Brannigan, J. A., Ruiz-Pérez, L. M., Wilson, K. S., González-Pacanowska, D. & Gilbert, I. H., 27 Dec 2012

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  11. 2011
  12. 2009
  13. Combining Hit Identification Strategies: Fragment-Based and in Silico Approaches to Orally Active 2-Aminothieno[2,3-d]pyrimidine Inhibitors of the Hsp90 Molecular Chaperone

    Brough, P. A., Barril, X., Borgognoni, J., Chene, P., Davies, N. G. M., Davis, B., Drysdale, M. J., Dymock, B., Eccles, S. A., Garcia-Echeverria, C., Fromont, C., Hayes, A., Hubbard, R. E., Jordan, A. M., Jensen, M. R., Massey, A., Merrett, A., Padfield, A., Parsons, R., Radimerski, T. & 13 others, Raynaud, F. I., Robertson, A., Roughley, S. D., Schoepfer, J., Simmonite, H., Sharp, S. Y., Surgenor, A., Valenti, M., Walls, S., Webb, P., Wood, M., Workman, P. & Wright, L., 13 Aug 2009

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  14. 2008
  15. 4,5-diarylisoxazole HSP90 chaperone inhibitors: potential therapeutic agents for the treatment of cancer

    Brough, P. A., Aherne, W., Barril, X., Borgognoni, J., Boxall, K., Cansfield, J. E., Cheung, K-M. J., Collins, I., Davies, N. G. M., Drysdale, M. J., Dymock, B., Eccles, S. A., Finch, H., Fink, A., Hayes, A., Howes, R., Hubbard, R. E., James, K., Jordan, A. M., Lockie, A. & 17 others, Martins, V., Massey, A., Matthews, T. P., McDonald, E., Northfield, C. J., Pearl, L. H., Prodromou, C., Ray, S., Raynaud, F. I., Roughley, S. D., Sharp, S. Y., Surgenor, A., Walmsley, D. L., Webb, P., Wood, M., Workman, P. & Wrightt, L., 24 Jan 2008

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  16. 2005
  17. Novel, potent small-molecule inhibitors of the molecular chaperone Hsp90 discovered through structure-based design

    Dymock, B. W., Barril, X., Brough, P. A., Cansfield, J. E., Massey, A., McDonald, E., Hubbard, R. E., Surgenor, A., Roughley, S. D., Webb, P., Workman, P., Wright, L. & Drysdale, M. J., 30 Jun 2005

    Article in JOURNAL OF MEDICINAL CHEMISTRY

  18. 1996
  19. 1987

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