Adrian Paul Mountford

Search results

• 2016

  Alternatively Activated Mononuclear Phagocytes from the Skin Site of Infection and the Impact of IL-4Rα Signalling on CD4+T Cell Survival in Draining Lymph Nodes after Repeated Exposure to Schistosoma mansoni Cercariae

  Prendergast, C. T., Sanin Pena, D. E. & Mountford, A. P., 9 Aug 2016, In: PLOS NEGLECTED TROPICAL DISEASES. 10, 8, 18 p., e0004911.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• CD4 T-cell hyporesponsiveness induced by schistosome larvae is not dependent upon eosinophils but may involve connective tissue mast cells

  Prendergast, C. T., Sanin Pena, D. E. & Mountford, A. P., 1 Feb 2016, In: Parasite immunology. 38, 2, p. 81-92 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2015

  CD4+ T cell hypo-responsiveness after repeated exposure to Schistosoma mansoni larvae is dependent upon interleukin-10

  Prendergast, C. T., Sanin, D., Cook, P. C. & Mountford, A. P., 26 Jan 2015, In: Infection and Immunity. 83, 4, p. 1418-1430 13 p.

  Research output: Contribution to journal › Article › peer-review

• Epidermal keratinocytes initiate wound healing and pro-inflammatory immune responses following percutaneous schistosome infection

  Bourke, C. D., Prendergast, C. T., Sanin Pena, D. E., Oulton, T. E., Hall, R. J. & Mountford, A. P., Mar 2015, In: International Journal for Parasitology. 45, 4, p. 215-224 10 p.

  Research output: Contribution to journal › Article › peer-review

• Helminth Infection and Commensal Microbiota Drive Early IL-10 Production in the Skin by CD4+ T Cells That Are Functionally Suppressive

  Sanin Pena, D. E., Prendergast, C. T., Bourke, C. D. & Mountford, A. P., May 2015, In: PLOS PATHOGENS. 11, 5, e1004841.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism

  Sanin Pena, D. E., Prendergast, C. T. & Mountford, A. P., 1 Aug 2015, In: Journal of Immunology. 195, 3, p. 1218-1232 15 p.

  Research output: Contribution to journal › Article › peer-review

• Sm16, a major component of Schistosoma mansoni cercarial excretory/secretory products, prevents macrophage classical activation and delays antigen processing

  Sanin, D. E. & Mountford, A. P., 6 Jan 2015, In: Parasites & vectors. 8, 1, 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2014

  Circulating CD14brightCD16+ 'intermediate' monocytes exhibit enhanced parasite pattern recognition in human helminth infection.

  Turner, J. D., Bourke, C. D., Meurs, L., Mbow, M., Dièye, T. N., Mboup, S., Polman, K. & Mountford, A. P., Apr 2014, In: PLOS NEGLECTED TROPICAL DISEASES. 8, 4

  Research output: Contribution to journal › Article › peer-review
• 2013

  Schistosome infection is associated with enhanced whole blood IL-10 secretion in response to cercarial excretory/secretory products

  Turner, J. D., Meurs, L., Dool, P., Bourke, C. D., Mbow, M., Dièye, T. N., Mboup, S., Polman, K. & Mountford, A. P., 12 Feb 2013, In: Parasite immunology. 35, 5-6, p. 147-156 10 p.

  Research output: Contribution to journal › Article › peer-review

• 'Seeing is Believing'; the use of novel imaging approaches towards creating a greater understanding of parasite: host interactions

  Mountford, A. P., 15 Jul 2013, In: Parasite immunology. 35, 9-10, p. 245-247

  Research output: Contribution to journal › Article › peer-review
• 2012

  A therapeutically viable photo-activated manganese-based CO-releasing molecule (photo-CO-RM)

  Ward, J. S., Lynam, J. M., Moir, J. W. B., Sanin, D. E., Mountford, A. P. & Fairlamb, I. J. S., 21 Sept 2012, In: Dalton Transactions. 41, 35, p. 10514-10517 4 p.

  Research output: Contribution to journal › Article › peer-review

• Blood Flukes Exploit Peyer's Patch Lymphoid Tissue to Facilitate Transmission from the Mammalian Host

  Turner, J. D., Narang, P., Coles, M. C. & Mountford, A. P., 20 Dec 2012, In: PLOS PATHOGENS. 8, 12, p. 1-10 10 p., e1003063.

  Research output: Contribution to journal › Article › peer-review

• Plasma membrane proteomes of differentially matured dendritic cells identified by LC-MS/MS combined with iTRAQ labelling

  Ferret-Bernard, S., Castro-Borges, W., Dowle, A. A., Sanin, D. E., Cook, P. C., Turner, J. D., MacDonald, A. S., Thomas, J. R. & Mountford, A. P., 4 Jan 2012, In: JOURNAL OF PROTEOMICS. 75, 3, p. 938-48 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2011

  CD4CD25 Regulatory Cells Contribute to the Regulation of Colonic Th2 Granulomatous Pathology Caused by Schistosome Infection

  Turner, J. D., Jenkins, G. R., Hogg, K. G., Aynsley, S. A., Paveley, R. A., Cook, P. C., Coles, M. C. & Mountford, A. P., Aug 2011, In: PLOS NEGLECTED TROPICAL DISEASES. 5, 8, p. 1-11 11 p., e1269.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Enhanced pro-inflammatory cytokine responses following Toll-like-receptor ligation in Schistosoma haematobium-infected schoolchildren from rural Gabon

  Meurs, L., Labuda, L., Amoah, A. S., Mbow, M., Ngoa, U. A., Boakye, D. A., Mboup, S., Dièye, T. N., Mountford, A. P., Turner, J. D., Kremsner, P. G., Polman, K., Yazdanbakhsh, M. & Adegnika, A. A., 8 Sept 2011, In: PLoS ONE. 6, 9, p. e24393 e24393.

  Research output: Contribution to journal › Article › peer-review

• Multiple helminth infection of the skin causes lymphocyte hypo-responsiveness mediated by Th2 conditioning of dermal myeloid cells

  Cook, P. C., Aynsley, S. A., Turner, J. D., Jenkins, G. R., Van Rooijen, N., Leeto, M., Brombacher, F. & Mountford, A. P., Mar 2011, In: PLOS PATHOGENS. 7, 3, p. 1-14 14 p., e1001323.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• The Mannose Receptor (CD206) is an important pattern recognition receptor (PRR) in the detection of the infective stage of the helminth Schistosoma mansoni and modulates IFNγ production

  Paveley, R. A., Aynsley, S. A., Turner, J. D., Bourke, C. D., Jenkins, S. J., Cook, P. C., Martinez-Pomares, L. & Mountford, A. P., Nov 2011, In: International Journal for Parasitology. 41, 13-14, p. 1335-45 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2010

  IL-10 secretion from CD14+ peripheral blood mononuclear cells is down regulated in patients with acne vulgaris. IL-10 is down-regulated in acne patients.

  Caillon, F., O'Connell, M., Eady, A., Cove, J., Layton, A. & Mountford, A. P., 2010, In: British Journal of Dermatology. 162, 2, p. 296-303 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2009

  Fluorescent Imaging of Antigen Released by a Skin-Invading Helminth Reveals Differential Uptake and Activation Profiles by Antigen Presenting Cells

  Paveley, R. A., Aynsley, S. A., Cook, P. C., Turner, J. D. & Mountford, A. P., Oct 2009, In: PLOS NEGLECTED TROPICAL DISEASES. 3, 10, p. 1-14 14 p., e528.

  Research output: Contribution to journal › Article › peer-review

• S. haematobium-infected Gabonese schoolchildren have elevated pro-inflammatory cytokine responses to single Toll-like-receptor ligands

  Meurs, L., Labuda, L., Amoah, A. S., Mbow, M., Ateba, U., Polman, K., Yazdanbakhsh, M., Boakye, D., Mboup, S., Dieye, T. N., Mountford, A. & Adegnika, A. A., Sept 2009, In: Tropical Medicine and International Health. 14, s2, p. 192-192 1 p.

  Research output: Contribution to journal › Article › peer-review

• The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti

  Dolecková, K., Kasný, M., Mikes, L., Cartwright, J., Jedelský, P., Schneider, E. L., Dvorák, J., Mountford, A. P., Craik, C. S. & Horák, P., 15 Jan 2009, In: International Journal for Parasitology. 39, 2, p. 201-11 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2008

  Antibody responses induced by Trichobilharzia regenti antigens in murine and human hosts exhibiting cercarial dermatitis

  Lichtenbergová, L., Kolbeková, P., Kourilová, P., Kasný, M., Mikes, L., Haas, H., Schramm, G., Horák, P., Kolárová, L. & Mountford, A. P., Nov 2008, In: Parasite immunology. 30, 11-12, p. 585-95 11 p.

  Research output: Contribution to journal › Article › peer-review

• Proteomic profiling reveals that Th2-inducing dendritic cells stimulated with helminth antigens have a 'limited maturation' phenotype

  Ferret-Bernard, S., Curwen, R. S. & Mountford, A. P., Mar 2008, In: Proteomics. 8, 5, p. 980-993 14 p.

  Research output: Contribution to journal › Article › peer-review
• 2007

  Alternative activated macrophages contribute to CD4(+) cell hypo-responsiveness following multiple infections with schistosome larvae

  Cook, P. C., Jenkins, G. R. & Mountford, A. P., Mar 2007, In: Immunology. 120, p. 61-61 1 p.

  Research output: Contribution to journal › Article › peer-review

• A novel method to visualise the interaction between schistosome larvae and cells of the innate immune response

  Paveley, R. A., Ferret-Bernard, S. & Mountford, A. P., Mar 2007, In: Immunology. 120, p. 47-47 1 p.

  Research output: Contribution to journal › Article › peer-review

• CD207(+) Langerhans cells constitute a minor population of skin-derived antigen-presenting cells in the draining lymph node following exposure to Schistosoma mansoni

  Kumkate, S., Jenkins, G. R., Paveley, R. A., Hogg, K. G. & Mountford, A. P., Feb 2007, In: International Journal for Parasitology. 37, 2, p. 209-220 12 p.

  Research output: Contribution to journal › Article › peer-review

• In the absence of CD154, administration of interleukin-12 restores Th1 responses but not protective immunity to Schistosoma mansoni

  Hewitson, J. P., Hamblin, P. A. & Mountford, A. P., Jul 2007, In: Infection and Immunity. 75, 7, p. 3539-3547 9 p.

  Research output: Contribution to journal › Article › peer-review

  File

• Peptidases of Trichobilharzia regenti (Schistosomatidae) and its molluscan host Radix peregra S. Lat. (Lymnaeidae): construction and screening of cDNA library from intramolluscan stages of the parasite

  Dolecková, K., Kasný, M., Mikes, L., Mutapi, F., Stack, C., Mountford, A. P. & Horák, P., 2007, In: Folia parasitologica. 54, 2, p. 94-8 5 p.

  Research output: Contribution to journal › Article › peer-review

• Proteomic study of differentially matured dendritic cells

  Ferret-Bernard, S., Curwen, R. S. & Mountford, A. P., Mar 2007, In: Immunology. 120, p. 58-58 1 p.

  Research output: Contribution to journal › Article › peer-review

• 2006

  CD40/CD154 interactions are required for the optimal maturation of skin-derived APCs and the induction of helminth-specific IFN-gamma but not IL-4

  Hewitson, J. P., Jenkins, G. R., Hamblin, P. A. & Mountford, A. P., 1 Sept 2006, In: Journal of Immunology. 177, 5, p. 3209-3217 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2005

  Dendritic cells activated with products released by schistosome larvae drive Th2-type immune responses, which can be inhibited by manipulation of CD40 costimulation

  Jenkins, S. J. & Mountford, A. P., Jan 2005, In: Infection and Immunity. 73, 1, p. 395-402 8 p.

  Research output: Contribution to journal › Article › peer-review

  File

• Hypo-responsiveness of CD4+ cells during chronic Schistosoma mansoni infection: relative roles of CD4+CD25+, CD4+CD25 and antigen presenting cells

  Jenkins, G. R., Cook, P. C. & Mountford, A. P., Dec 2005, In: Immunology. 116, p. 104-104 1 p.

  Research output: Contribution to journal › Article › peer-review

• Immunity induced by the radiation-attenuated schistosome vaccine

  Hewitson, J. P., Hamblin, P. A. & Mountford, A. P., 6 Sept 2005, In: Parasite immunology. 27, 7-8, p. 271-280 10 p.

  Research output: Contribution to journal › Article › peer-review

• Modulation of the host's immune response by schistosome larvae

  Hewitson, J. P., Jenkins, G. R. & Mountford, A. P., 24 Sept 2005, In: Parasite immunology. 27, 10-11, p. 385-393 9 p.

  Research output: Contribution to journal › Article › peer-review

• Multiple exposures of mice to larvae of Schistosoma mansoni cause CD4(+) hyporesponsiveness

  Cook, P. C., Jenkins, G. R. & Mountford, A. P., Dec 2005, In: Immunology. 116, p. 26-26 1 p.

  Research output: Contribution to journal › Article › peer-review

• Proteomic study of differentially matured dendritic cells

  Ferret-Bernard, S., Jenkins, S. J. & Mountford, A. P., Dec 2005, In: Immunology. 116, p. 23-23 1 p.

  Research output: Contribution to journal › Article › peer-review

• Schistosome larvae stimulate macrophage cytokine production through TLR4-dependent and -independent pathways

  Jenkins, S. J., Hewitson, J. P., Ferret-Bernard, S. & Mountford, A. P., Nov 2005, In: International immunology. 17, 11, p. 1409-1418 10 p.

  Research output: Contribution to journal › Article › peer-review
• 2004

  Cercarial dermatitis caused by bird schistosomes comprises both immediate and late phase cutaneous hypersensitivity reactions

  Kouilová, P., Hogg, K. G., Koláová, L. & Mountford, A. P., 15 Mar 2004, In: Journal of Immunology. 172, 6, p. 3766-3774 8 p.

  Research output: Contribution to journal › Article › peer-review

• Schistosomes in the skin: a balance between immune priming and regulation

  Mountford, A. P. & Trottein, F., May 2004, In: Trends in parasitology. 20, 5, p. 221-226 6 p.

  Research output: Contribution to journal › Article › peer-review
• 2003

  IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine

  Hogg, K. G., Kumkate, S. & Mountford, A. P., Dec 2003, In: International immunology. 15, 12, p. 1451-1459 9 p.

  Research output: Contribution to journal › Article › peer-review

• IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni

  Linehan, S. A., Coulson, P. S., Wilson, R. A., Mountford, A. P., Brombacher, F., Martinez-Pomares, L. & Gordon, S., Aug 2003, In: Laboratory investigation. 83, 8, p. 1223-1231 9 p.

  Research output: Contribution to journal › Article › peer-review

• Interleukin-12 p40 secretion by cutaneous CD11c(+) and F4/80(+) cells is a major feature of the innate immune response in mice that develop Th1-mediated protective immunity to Schistosoma mansoni

  Hogg, K. G., Kumkate, S., Anderson, S. & Mountford, A. P., Jun 2003, In: Infection and Immunity. 71, 6, p. 3563-3571 9 p.

  Research output: Contribution to journal › Article › peer-review

  File
• 2001

  Signaling via interleukin-4, receptor alpha chain is required for successful vaccination against schistosomiasis in BALB/c mice

  Mountford, A. P., Coulson, P. S., Hogg, K. G. & Brombacher, F., 2001, In: Infection and Immunity. 69, 1, p. 228-236 8 p.

  Research output: Contribution to journal › Article › peer-review

  File
• 2000

  IL-18 potentiates the adjuvant properties of IL-12 in the induction of a strong Th1 type immune response against a recombinant antigen

  Eberl, M., Beck, E., Coulson, P. S., Okamura, H., Wilson, R. A. & Mountford, A. P., 2000, In: Vaccine. 18, 19, p. 2002-8 7 p.

  Research output: Contribution to journal › Article › peer-review

• 1999

  Formation of multinucleated giant cells in the mouse lung is promoted in the absence of interleukin-12

  Anderson, S., Shires, V. L., Wilson, R. A. & Mountford, A. P., 1999, In: American journal of respiratory cell and molecular biology. 20, 3, p. 371-8 8 p.

  Research output: Contribution to journal › Article › peer-review

• Immune responses to the radiation-attenuated schistosome vaccine: what can we learn from knock-out mice?

  Wilson, R. A., Coulson, P. S. & Mountford, A. P., Jan 1999, In: Immunology letters. 65, 1-2, p. 117-123 7 p.

  Research output: Contribution to journal › Article › peer-review

• Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling to downregulate T-helper 2 responses

  Mountford, A. P., Coulson, P. S., Wynn, T. A., Cheever, A. W., Sher, A. & Wilson, R. A., Aug 1999, In: Immunology. 97, 4, p. 588-594 6 p.

  Research output: Contribution to journal › Article › peer-review

• Isolation of T-cell antigens by using a recombinant protein library and its application to the identification of novel vaccine candidates against schistosomiasis

  Eberl, M., Mountford, A. P., Jankovic, D. & Beck, E., Jul 1999, In: Infection and Immunity. 67, 7, p. 3383-3389 7 p.

  Research output: Contribution to journal › Article › peer-review

• The radiation-attenuated schistosome vaccine induces high levels of protective immunity in the absence of B cells

  Anderson, S., Coulson, P. S., Ljubojevic, S., Mountford, A. P. & Wilson, R. A., Jan 1999, In: Immunology. 96, 1, p. 22-28 7 p.

  Research output: Contribution to journal › Article › peer-review
• 1998

  Interleukin-12 and protective immunity to schistosomes

  Mountford, A. P., Shires, V. L. & Anderson, S., Jan 1998, In: Brazilian journal of medical and biological research. 31, 1, p. 163-169 7 p.

  Research output: Contribution to journal › Article › peer-review