Research output per year
Research output per year
- 13 results
Search results
-
2023
Cyclosulfamidate Mannose-Configured Cyclitol Allows Specific Allele-Dependent Inhibition of GH47 α-D-Mannosidases Through a Bump-Hole Strategy
Males, A., Kok, K., Nin-Hill, A., Beukel, S. V. D., Beenakker, T. J. M., van der Marel, G. A., Codée, J. D. C., Overkleeft, H. S., Rovira, C., Davies, G. J. & Artola, M., 17 Nov 2023, In: Chemical Science. 14, p. 13581-13586 6 p.Research output: Contribution to journal › Article › peer-review
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Human O-GlcNAcase Uses a Preactivated Boat-like Substrate Conformation for Catalysis: Evidence from X-ray Crystallography and QM/MM Metadynamics
Calvelo, M., Males, A., Alteen, M. G., Willems, L. I., Vocadlo, D. J., Davies, G. J. & Rovira, C., 10 Oct 2023, (E-pub ahead of print) In: ACS Catalysis. 13, p. 13672–13678Research output: Contribution to journal › Article › peer-review
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Structure, function and mechanism of N-glycan processing enzymes: endo-α-1,2-mannanase and endo-α-1,2-mannosidase
Burchill, L., Males, A., Kaur, A., Davies, G. J. & Williams, S. J., 1 Feb 2023, In: Israel Journal of Chemistry. 63, 1-2, 13 p., e202200067.Research output: Contribution to journal › Article › peer-review
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2022
Bicyclic picomolar OGA inhibitors enable chemoproteomic mapping of its endogenous post-translational modifications
González-Cuest, M., Sidhu, P., Ashmus, R. A., Males, A., Proceviat, C., Madden, Z., Rogalski, J. C., Busmann, J. A., Foster, L. J., Fernández, J. M. G., Davies, G. J., Mellet, C. O. & Vocadlo, D. J., 19 Jan 2022, In: Journal of the American Chemical Society. 144 , 2, p. 832–844 13 p.Research output: Contribution to journal › Article › peer-review
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2021
The development of non-hydrolysable oligosaccharide activity-based inactivators for endoglycanases: a case study on a-1,6 mannanases
Schröder, S. P., Offen, W. A., Males, A., Jin, Y., Boer, C. D., Enotarpi, J., Marino, L., van der Marel, G. A., Florea, B. I., Codée, J. D. C., Overkleeft, H. S. & Davies, G. J., 21 May 2021, (E-pub ahead of print) In: Chemistry A European Journal. 6 p.Research output: Contribution to journal › Article › peer-review
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2020
Mannosidase mechanism: at the intersection of conformation and catalysis
Rovira, C., Males, A., Davies, G. J. & Williams, S. J., 1 Jun 2020, In: CURRENT OPINION IN STRUCTURAL BIOLOGY. 62, p. 79-92 14 p.Research output: Contribution to journal › Review article › peer-review
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2019
A family of dual-activity glycosyltransferasesphosphorylases mediates mannogen turnover and virulence in Leishmania parasites
Sernee, M. F., Ralton, J. E., Nero, T. L., Sobala, L. F., Kloehn, J., Viera-Lara, M., Cobbold, S. A., Stanton, L., Pires, D. E. V., Hanssen, E., Males, A., Ward, T., Bastidas, L. M., Peet, P. L. V. D., Parker, M. W., Ascher, D. B., Williams, S. J., Davies, G. J. & McConville, M. J., 11 Sept 2019, In: Cell Host & Microbe. 26, 3, p. 385-399 15 p.Research output: Contribution to journal › Article › peer-review
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Distortion of mannoimidazole supports a B 2,5 boat transition state for the family GH125 α-1,6-mannosidase from Clostridium perfringens
Males, A., Speciale, G., Williams, S. J. & Davies, G. J., 13 Aug 2019, (E-pub ahead of print) In: Organic and Biomolecular Chemistry. 7 p.Research output: Contribution to journal › Article › peer-review
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Molecular mechanisms regulating O-linked N-acetylglucosamine (O-GlcNAc)–processing enzymes
King, D., Males, A., Davies, G. J. & Vocadlo, D., 1 Dec 2019, In: Current Opinion in Chemical Biology. 53, p. 131-144Research output: Contribution to journal › Article › peer-review
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Structural studies of a surface-entropy reduction mutant of O-GlcNAcase
Males, A. & Davies, G. J., 8 Jan 2019, In: Acta crystallographica. Section D, Structural biology. 75, 1, p. 70-78 9 p.Research output: Contribution to journal › Article › peer-review
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2017
Computational design-of-experiment unveils the conformational reaction coordinate of GH125 α-mannosidases
Alonso-Gil, S., Males, A., Fernandes, P., Williams, S. J., Davies, G. J. & Rovira, C., 25 Jan 2017, In: Journal of the American Chemical Society. 139, 3, p. 1085–1088 4 p., ja-2016-11247.Research output: Contribution to journal › Article › peer-review
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Conformational analysis of the mannosidase inhibitor kifunensine: a quantum mechanical and structural approach
Males, A., Raich, L., Williams, S. J., Rovira, C. & Davies, G. J., 11 May 2017, (E-pub ahead of print) In: Chembiochem. p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review
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Conformational behaviour of mannuronic acid based azasugars
van Rijssel, E., Janssen, A. P. A., Males, A., Davies, G. J., Van der Marel, G. A., Overkleeft, H. S. & Codee, J. D. C., 3 Mar 2017, (E-pub ahead of print) In: Chembiochem. p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
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