Anne Routledge

Search results

• 2022

  Synthesis and antimicrobial activity of an SO2-releasing siderophore conjugate

  Black, C., Chu, A. J., Thomas, G. H., Routledge, A. & Duhme-Klair, A.-K., Sept 2022, In: JOURNAL OF INORGANIC BIOCHEMISTRY. 234, 12 p., 111875.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2020

  A Salmochelin S4-inspired Ciprofloxacin Trojan Horse Conjugate

  Sanderson, T., Black, C., Southwell, J., Wilde, E., Pandey, A., Herman, R., Thomas, G. H., Boros, E., Duhme-Klair, A. K. & Routledge, A., 11 Sept 2020, In: ACS Infectious Diseases. 6, 9, p. 2532–2541

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Investigation of Parameters that Affect Resin Swelling in Green Solvents

  Amadi-Kamalu, C., Clarke, H., McRobie, M., Mortimer, J., North, M., Ran, Y., Routledge, A., Sibbald, D., Tickias, M., Tse, K. & Willway, H., 3 Apr 2020, In: ChemistryOpen. 9, 4, p. 431-441 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2019

  Mimicking salmochelin S1 and the interactions of its Fe(III) complex with periplasmic iron siderophore binding proteins CeuE and VctP

  Wilde, E. J., Blagova, E. V., Sanderson, T. J., Raines, D. J., Thomas, R. P., Routledge, A., Duhme-Klair, A.-K. & Wilson, K. S., Jan 2019, In: JOURNAL OF INORGANIC BIOCHEMISTRY. 190, p. 75-84 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2017

  Greener solvents for solid-phase synthesis

  Lawrenson, S., North, M., Peigneguy, F. & Routledge, A., 21 Feb 2017, In: Green Chemistry. 19, 4, p. 952-962 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2016

  Fabrication and Application of Isotopically Labelled Gold Arrays for Multiplexed Peptide Analysis

  Castangia, R., Hudson, S., Robinson, H., Flitsch, S., Thomas-Oates, J. & Routledge, A., 12 Sept 2016, (E-pub ahead of print) In: Chembiochem. 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2014

  Probing bacterial uptake of glycosylated ciprofloxacin conjugates

  Milner, S. J., Carrick, C. T., Kerr, K. G., Snelling, A. M., Thomas, G. H., Duhme-Klair, A.-K. & Routledge, A., 10 Feb 2014, In: Chembiochem. 15, 3, p. 466-471 6 p.

  Research output: Contribution to journal › Article › peer-review

• Probing linker design in citric acid-ciprofloxacin conjugates

  Milner, S. J., Snelling, A. M., Kerr, K. G., Abd-El-Aziz, A., Thomas, G. H., Hubbard, R. E., Routledge, A. & Duhme-Klair, A. K., 15 Aug 2014, In: Bioorganic & Medicinal Chemistry. 22, 16, p. 4499-4505 7 p.

  Research output: Contribution to journal › Article › peer-review
• 2013

  Staphyloferrin A as siderophore-component in fluoroquinolone-based Trojan horse antibiotics

  Milner, S. J., Seve, A., Snelling, A. M., Thomas, G. H., Kerr, K. G., Routledge, A. & Duhme-Klair, A.-K., 11 Apr 2013, In: Organic and Biomolecular Chemistry. 11, 21, p. 3461-3468 8 p.

  Research output: Contribution to journal › Article › peer-review
• 2012

  Evaluation of a Solid-Supported Tagging Strategy for Mass Spectrometric Analysis of Peptides

  Hudson, S. R., Chadbourne, F. L., Helliwell, P. A., Pflimlin, E., Thomas-Oates, J. E. & Routledge, A., 13 Feb 2012, In: Acs combinatorial science. 14, 2, p. 97-100 4 p.

  Research output: Contribution to journal › Article › peer-review
• 2010

  A mass spectrometric investigation into microenvironmental effects in solid-supported radical chemistry

  Helliwell, P. A., Bailey, V. A., Chevet, C., Clarke, D. B., Lloyd, A., Macarthur, R. & Routledge, A., Feb 2010, In: Reactive and Functional Polymers. 70, 2, p. 110-115 6 p.

  Research output: Contribution to journal › Article › peer-review

• Dietary intake estimate for perfluorooctanesulphonic acid (PFOS) and other perfluorocompounds (PFCs) in UK retail foods following determination using standard addition LC-MS/MS

  Clarke, D. B., Bailey, V. A., Routledge, A., Lloyd, A. S., Hird, S., Mortimer, D. N. & Gem, M., Apr 2010, In: FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE. 27, 4, p. 530-545 16 p.

  Research output: Contribution to journal › Article › peer-review

• Extraction of perfluorinated compounds from food matrices using fluorous solvent partitioning

  Bailey, V. A., Clarke, D. & Routledge, A., Jun 2010, In: JOURNAL OF FLUORINE CHEMISTRY. 131, 6, p. 691-697 7 p.

  Research output: Contribution to journal › Article › peer-review

• Microwave-Assisted Synthesis of Aryl Amide Bonds on Solid Phase

  Helliwell, P. A., Fake, R. E., Kerr, K. G., Santry, B., Speakman, A. & Routledge, A., Jan 2010, In: SYNTHETIC COMMUNICATIONS. 40, 20, p. 3058-3066 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2009

  Mass spectral studies towards more reliable measurement of perfluorooctanesulfonic acid and other perfluorinated chemicals (PFCs) in food matrices using liquid chromatography/tandem mass spectrometry

  Lloyd, A. S., Bailey, V. A., Hird, S. J., Routledge, A. & Clarke, D. B., 30 Sept 2009, In: Rapid Communications in Mass Spectrometry. 23, 18, p. 2923-2938 16 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis, chemical stability and application of a thiohydroxamic acid linker (THA) for solid-phase organic synthesis

  Whitehead, D. M., Helliwell, P. A., McKeown, S. C. & Routledge, A., Dec 2009, In: Reactive and Functional Polymers. 69, 12, p. 884-890 7 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis of citrate-ciprofloxacin conjugates

  Md-Saleh, S. R., Chilvers, E. C., Kerr, K. G., Milner, S. J., Snelling, A. M., Weber, J. P., Thomas, G. H., Duhme-Klair, A.-K. & Routledge, A., 1 Mar 2009, In: Bioorganic & Medicinal Chemistry Letters. 19, 5, p. 1496-1498 3 p.

  Research output: Contribution to journal › Article › peer-review
• 2007

  Siderophore-Drug Conjugates as Novel Antimicrobial Agents

  Md-Saleh, S. R., Duhme-Klair, A. & Routledge, A., 2007, In: JOURNAL OF INORGANIC BIOCHEMISTRY. 12, p. S39

  Research output: Contribution to journal › Article › peer-review

• 2006

  Radical addition reactions of phosphorus hydrides: Tuning the reactivity of phosphorus hydrides, the use of microwaves and Horner-Wadsworth-Emmons-type reactions

  Jessop, C. M., Parsons, A. F., Routledge, A. & Irvine, D. J., 13 Mar 2006, In: European Journal of Organic Chemistry. 6, p. 1547-1554 8 p.

  Research output: Contribution to journal › Article › peer-review
• 2005

  A cleaner approach to solid-supported radical chemistry: Application of hypophosphite salts to intramolecular C-C bond formation on the solid-phase

  Chevet, C., Jackson, T., Santry, B. & Routledge, A., 16 Feb 2005, In: Synlett. 3, 3, p. 477-480 4 p.

  Research output: Contribution to journal › Article › peer-review

• Characterisation and proposed origin of mass spectrometric ions observed 30Th above the ionised molecules of per-O-methylated carbohydrates

  Robinson, S., Routledge, A. & Thomas-Oates, J., 2005, In: Rapid Communications in Mass Spectrometry. 19, 24, p. 3681-3688 8 p.

  Research output: Contribution to journal › Article › peer-review

• Recent advances in analytical construct resins

  Whitehead, D. M., McKeown, S. C. & Routledge, A., Jun 2005, In: Journal Of Combinatorial Chemistry. 8, 4, p. 361-371 11 p.

  Research output: Contribution to journal › Article › peer-review

• 2004

  Phosphonyl radical addition to enol ethers. The stereoselective synthesis of cyclic ethers

  Jessop, C. M., Parsons, A. F., Routledge, A. & Irvine, D. J., 21 Jun 2004, In: Tetrahedron Letters. 45, 26, p. 5095-5098 4 p.

  Research output: Contribution to journal › Article › peer-review

• Rapid detection of hydroxyl groups on solid-phase

  Fake, R. E. & Routledge, A., 22 Nov 2004, In: Tetrahedron Letters. 45, 48, p. 8925-8926 2 p.

  Research output: Contribution to journal › Article › peer-review
• 2003

  Cyclisation of dienes using phosphorus-centred radicals to form organophosphorus adducts

  Jessop, C. M., Parsons, A. F., Routledge, A. & Irvine, D., 13 Jan 2003, In: Tetrahedron Letters. 44, 3, p. 479-483 5 p.

  Research output: Contribution to journal › Article › peer-review

• Radical addition reactions of chiral phosphorus hydrides

  Jessop, C. M., Parsons, A. F., Routledge, A. & Irvine, D. J., 3 Oct 2003, In: TETRAHEDRON-ASYMMETRY. 14, 19, p. 2849-2851 3 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis and application of crown ether tagged triarylphosphines

  Jackson, T. & Routledge, A., 3 Feb 2003, In: Tetrahedron Letters. 44, 6, p. 1305-1307 3 p.

  Research output: Contribution to journal › Article › peer-review
• 2002

  Application of x-ray photoelectron spectroscopy in determining the structure of solid-phase bound substrates

  Whitehead, D. M., Jackson, T., McKeown, S. C., Wilson, K. & Routledge, A., 1 Jul 2002, In: Journal Of Combinatorial Chemistry. 4, 4, p. 255-257 3 p.

  Research output: Contribution to journal › Article › peer-review

• The application of a thiohydroxamic acid (THA) linker in the solid-phase synthesis of a urea library

  Whitehead, D. M., Jackson, T., McKeown, S. C. & Routledge, A., 2002, In: Reactive and Functional Polymers. 52, 2, p. 81-87 7 p.

  Research output: Contribution to journal › Article › peer-review
• 2000

  A photolabile 'traceless' linker for solid-phase organic synthesis

  Horton, J. R., Stamp, L. M. & Routledge, A., 18 Nov 2000, In: Tetrahedron Letters. 41, 47, p. 9181-9184 4 p.

  Research output: Contribution to journal › Article › peer-review

• 1997

  An Investigation into Solid-Phase Radical Chemistry - Synthesis of Furan Rings

  Routledge, A., Abell, C. & Balasubramanian, S., Jan 1997, In: Synlett. 1, p. 61-62 2 p.

  Research output: Contribution to journal › Article › peer-review

• New fluoride-labile linkers for solid-phase organic synthesis

  Routledge, A., Stock, H. T., Flitsch, S. L. & Turner, N. J., 24 Nov 1997, In: Tetrahedron Letters. 38, 47, p. 8287-8290 4 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis of 2-oxindole derivatives via the intramolecular Heck reaction on solid support

  Arumugam, V., Routledge, A., Abell, C. & Balasubramanian, S., 8 Sept 1997, In: Tetrahedron Letters. 38, 36, p. 6473-6476 4 p.

  Research output: Contribution to journal › Article › peer-review

• The use of a dithiane protected benzoin photolabile safety catch linker for solid-phase synthesis.

  Routledge, A., Abell, C. & Balasubramanian, S., 17 Feb 1997, In: Tetrahedron Letters. 38, 7, p. 1227-1230 4 p.

  Research output: Contribution to journal › Article › peer-review

• 1996

  Solid phase synthesis of a mitozolomide-oligonucleotide conjugate using a novel silyl-linked solid support

  Walsh, A. J., Ross, K. C., Routledge, A., Wallis, M. P. & Fraser, W., 1 Dec 1996, In: Pharmaceutical Sciences. 2, 1, p. 33-38 6 p.

  Research output: Contribution to journal › Article › peer-review

• The glycosidic precursor of (Z)-5-ethylidene-2(5H)-furanone in Halocarpus biformis juvenile foliage

  Perry, N. B., Benn, M. H., Foster, L. M., Routledge, A. & Weavers, R. T., May 1996, In: PHYTOCHEMISTRY. 42, 2, p. 453-459 7 p.

  Research output: Contribution to journal › Article › peer-review
• 1995

  A new deprotection strategy for automated oligonucleotide synthesis using a novel silyl-linked solid support

  Routledge, A., Wallis, M. P., Ross, K. C. & Fraser, W., 21 Sept 1995, In: Bioorganic & Medicinal Chemistry Letters. 5, 18, p. 2059-2064 6 p.

  Research output: Contribution to journal › Article › peer-review

• Iodomethylene lactone formation: An improved synthesis

  Mawson, S. D., Routledge, A. & Weavers, R. T., 17 Apr 1995, In: Tetrahedron. 51, 16, p. 4665-4678 14 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis, bioactivation and anti-HIV activity of 4-acyloxybenzyl bis(nucleosid-5'-yl) phosphates

  Routledge, A., Walker, I., Freeman, S., Hay, A. & Mahmood, N., 1995, In: Nucleosides and Nucleotides. 14, 7, p. 1545-1558 14 p.

  Research output: Contribution to journal › Article › peer-review

• Synthesis of mono- and dimannoside phosphoramidite derivatives for solid-phase conjugation to oligonucleotides

  Akhtar, S., Routledge, A., Patel, R. & Gardiner, J. M., 2 Oct 1995, In: Tetrahedron Letters. 36, 40, p. 7333-7336 4 p.

  Research output: Contribution to journal › Article › peer-review
• 1994

  Reaction of iodoalkylidene lactones with nucleophiles

  Haaima, G., Mawson, S. D., Routledge, A. & Weavers, R. T., 14 Mar 1994, In: Tetrahedron. 50, 11, p. 3557-3570 14 p.

  Research output: Contribution to journal › Article › peer-review
• 1993

  Synthesis of iodoalkylidene lactones from alkenes

  Haaima, G., Lynch, M. J., Routledge, A. & Weavers, R. T., 1 Jan 1993, In: Tetrahedron. 49, 20, p. 4229-4252 24 p.

  Research output: Contribution to journal › Article › peer-review