Research output per year
Research output per year
- 34 results
Search results
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2024
Beyond co-expression: pathway discovery for plant pharmaceuticals
Swamidatta, S. H. & Lichman, B. R., Aug 2024, In: CURRENT OPINION IN BIOTECHNOLOGY. 88, 8 p., 103147.Research output: Contribution to journal › Review article › peer-review
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Incorporation of nitrogen in antinutritional Solanum alkaloid biosynthesis
Grzech, D., Smit, S. J., Alam, R. M., Boccia, M., Nakamura, Y., Hong, B., Barbole, R., Heinicke, S., Kunert, M., Seibt, W., Grabe, V., Caputi, L., Lichman, B. R., O’Connor, S. E., Aharoni, A. & Sonawane, P. D., 13 Sept 2024, In: NATURE CHEMICAL BIOLOGY. 19 p.Research output: Contribution to journal › Article › peer-review
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Pseudomolecule-scale genome assemblies of Drepanocaryum sewerzowii and Marmoritis complanata
Smit, S. J., Whitehead, C., James, S. R., Jeffares, D. C., Godden, G., Peng, D., Sun, H. & Lichman, B. R., 7 Oct 2024, In: G3: Genes, Genomes, Genetics. 14, 10, 10 p., jkae172.Research output: Contribution to journal › Article › peer-review
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Streamlined screening platforms lead to the discovery of pachysiphine synthase from Tabernanthe iboga
Kamileen, M. O., Nakamura, Y., Luck, K., Heinicke, S., Hong, B., Colinas, M., Lichman, B. R. & O'Connor, S. E., 16 Oct 2024, In: New Phytologist. 244, 4, p. 1437-1449Research output: Contribution to journal › Article › peer-review
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The genomic and enzymatic basis for iridoid biosynthesis in cat thyme (Teucrium marum)
Smit, S. J., Ayten, S., Radzikowska, B. A., Hamilton, J. P., Langer, S., Unsworth, W. P., Larson, T. R., Buell, C. R. & Lichman, B. R., 30 May 2024, In: The Plant journal. 14 p.Research output: Contribution to journal › Article › peer-review
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Variation of terpene alkaloids in Daphniphyllum macropodum across plants and tissues
Eljounaidi, K., Radzikowska, B. A., Whitehead, C. B., Taylor, D. J., Conde, S., Davis, W., Dowle, A. A., Langer, S., James, S., Unsworth, W. P., Ezer, D., Larson, T. R. & Lichman, B. R., Jul 2024, In: The New phytologist. 243, 1, p. 299-313 15 p.Research output: Contribution to journal › Article › peer-review
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2023
A chromosome-level genome assembly reveals that a bipartite gene cluster formed via an inverted duplication controls monoterpenoid biosynthesis in Japanese catnip
Liu, C., Smit, S., Dang, J., Zhou, P., Godden, G. T., Jiang, Z., Liu, W., Liu, L., Lin, W., Duan, J., Wu, Q. & Lichman, B. R., 6 Mar 2023, In: Molecular plant. 16, 16 p.Research output: Contribution to journal › Article › peer-review
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Structure and Mutation of Deoxypodophyllotoxin Synthase (DPS) from Podophyllum hexandrum
Ingold, Z., Grogan, G. J. & Lichman, B. R., 24 May 2023, In: Frontiers in Catalysis. 3, 10 p., 1178345.Research output: Contribution to journal › Article › peer-review
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2022
Ancestral Sequence Reconstruction for Exploring Alkaloid Evolution
Lichman, B. R., 23 Jun 2022, Catharanthus roseus: Methods and Protocols. Springer, p. 165-179 15 p. (Methods in molecular biology; vol. 2505).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Author Correction: Biocatalytic routes to stereo-divergent iridoids (Nature Communications, (2022), 13, 1, (4718), 10.1038/s41467-022-32414-w)
Hernández Lozada, N. J., Hong, B., Wood, J. C., Caputi, L., Basquin, J., Chuang, L., Kunert, M., Rodríguez López, C. E., Langley, C., Zhao, D., Buell, C. R., Lichman, B. R. & O’Connor, S. E., 27 Sept 2022, In: Nature Communications. 13, 1, 5678.Research output: Contribution to journal › Comment/debate
Open Access -
Biocatalytic routes to stereo-divergent iridoids
Hernández Lozada, N. J., Hong, B., Wood, J. C., Caputi, L., Basquin, J., Chuang, L., Kunert, M., Rodríguez López, C. E., Langley, C., Zhao, D., Buell, C. R., Lichman, B. R. & O’Connor, S. E., 11 Aug 2022, In: Nature Communications. 13, 1, 13 p., 4718.Research output: Contribution to journal › Article › peer-review
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Phylogeny-Aware Chemoinformatic Analysis of Chemical Diversity in Lamiaceae Enables Iridoid Pathway Assembly and Discovery of Aucubin Synthase
Rodríguez-López, C. E., Jiang, Y., Kamileen, M. O., Lichman, B. R., Hong, B., Vaillancourt, B., Buell, C. R. & O'Connor, S. E., 1 Apr 2022, In: Molecular Biology and Evolution. 39, 4, 18 p., msac057.Research output: Contribution to journal › Article › peer-review
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Plant biosynthetic gene clusters in the context of metabolic evolution
Smit, S. J. & Lichman, B. R., 1 Jul 2022, In: NATURAL PRODUCT REPORTS. 7, p. 1465-1482 18 p., 39.Research output: Contribution to journal › Review article › peer-review
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Recycling Upstream Redox Enzymes Expands the Regioselectivity of Cycloaddition in Pseudo-Aspidosperma Alkaloid Biosynthesis
Kamileen, M. O., Demars, M. D., Hong, B., Nakamura, Y., Paetz, C., Lichman, B. R., Sonawane, P. D., Caputi, L. & O'Connor, S. E., 2 Nov 2022, In: Journal of the American Chemical Society. 144, 43, p. 19673–19679 7 p.Research output: Contribution to journal › Article › peer-review
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2021
Cell-Free Total Biosynthesis of Plant Terpene Natural Products Using an Orthogonal Cofactor Regeneration System
Bat-Erdene, U., Billingsley, J. M., Turner, W. C., Lichman, B. R., Ippoliti, F. M., Garg, N. K., O'Connor, S. E. & Tang, Y., 6 Aug 2021, In: ACS Catalysis. 11, 15, p. 9898-9903 6 p.Research output: Contribution to journal › Article › peer-review
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Dreaming of clean bean protein
Eljounaidi, K. & Lichman, B. R., 5 Jul 2021, In: Nature Plants. 7, 7, p. 860-861 2 p.Research output: Contribution to journal › Article
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The scaffold-forming steps of plant alkaloid biosynthesis
Lichman, B. R., 3 Aug 2021, In: NATURAL PRODUCT REPORTS. 38, 1, p. 103-129 27 p.Research output: Contribution to journal › Review article › peer-review
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2020
Gene and genome duplications in the evolution of chemodiversity: perspectives from studies of Lamiaceae
Lichman, B. R., Godden, G. T. & Buell, C. R., Jun 2020, In: CURRENT OPINION IN PLANT BIOLOGY. 55, p. 74-83 10 p.Research output: Contribution to journal › Review article › peer-review
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Nature's Chemists: The Discovery and Engineering of Phytochemical Biosynthesis
Lichman, B. R. & Eljounaidi, K., 9 Nov 2020, In: Frontiers in Chemistry.Research output: Contribution to journal › Literature review › peer-review
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Single step syntheses of (1S)-aryl-tetrahydroisoquinolines by norcoclaurine synthases
Lichman, B. R., Roddan, R., Sula, A., Fabiana, S., Mendez-Sanchez, D., Broomfield, J., Richter, M., Andexer, J., Ward, J. M., Keep, N. H. & Hailes, H. C., 13 Nov 2020, In: Communications Chemistry. 3, 170, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
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The evolutionary origins of the cat attractant nepetalactone in catnip
Lichman, B. R., Godden, G., Hamilton, J., Palmer, L., Kamileen, M. O., Zhao, D., Vaillancourt, B., Wood, J. C., Sun, M., Kinser, T. J., Henry, L. K., Rodriguez-Lopez, C., Dudareva, N., Soltis, D. E., Soltis, P., Buell, C. R. & O'Connor, S. E., 13 May 2020, In: Science Advances. 6, 20, 14 p., eaba0721.Research output: Contribution to journal › Article › peer-review
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2019
Biocatalytic Strategies towards [4+2] Cycloadditions
Lichman, B. R., O'Connor, S. E. & Kries, H., 17 May 2019, In: Chemistry - A European Journal. 25, 28, p. 6864-6877 14 p.Research output: Contribution to journal › Review article › peer-review
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2018
Identification of iridoid synthases from Nepeta species: Iridoid cyclization does not determine nepetalactone stereochemistry
Sherden, N. H., Lichman, B., Caputi, L., Zhao, D., Kamileen, M. O., Buell, C. R. & O'Connor, S. E., 1 Jan 2018, In: PHYTOCHEMISTRY. 145, p. 48-56 9 p.Research output: Contribution to journal › Article › peer-review
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One-pot chemoenzymatic synthesis of trolline and tetrahydroisoquinoline analogues
Zhao, J., Lichman, B. R., Ward, J. M. & Hailes, H. C., 1 Jan 2018, In: Chemical Communications. 54, 11, p. 1323-1326 4 p.Research output: Contribution to journal › Article › peer-review
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Phylogenomic Mining of the Mints Reveals Multiple Mechanisms Contributing to the Evolution of Chemical Diversity in Lamiaceae
Mint Evolutionary Genomics Consortium, Boachon, B., Buell, C. R., Crisovan, E., Dudareva, N., Garcia, N., Godden, G., Henry, L., Kamileen, M. O., Kates, H. R., Lichman, B. R., Kilgore, M. B., Mavrodiev, E. V., Newton, L., Rodriguez-Lopez, C., O'Connor, S. E., Soltis, D., Soltis, P., Vaillancourt, B. & Wiegert-Rininger, K. & 1 others, , 6 Aug 2018, In: Molecular plant. 11, 8, p. 1084-1096 13 p.Research output: Contribution to journal › Article › peer-review
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Uncoupled activation and cyclization in catmint reductive terpenoid biosynthesis
Lichman, B. R., Kamileen, M. O., Titchiner, G. R., Saalbach, G., Stevenson, C. E. M., Lawson, D. M. & O’Connor, S. E., 10 Dec 2018, In: NATURE CHEMICAL BIOLOGY. 15, 1, p. 71-79 8 p.Research output: Contribution to journal › Article › peer-review
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2017
A transatlantic perspective on 20 emerging issues in biological engineering
Wintle, B. C., Boehm, C. R., Rhodes, C., Molloy, J. C., Millett, P., Adam, L., Breitling, R., Carlson, R., Casagrande, R., Dando, M., Doubleday, R., Drexler, E., Edwards, B., Ellis, T., Evans, N. G., Hammond, R., Haseloff, J., Kahl, L., Kuiken, T. & Lichman, B. R. & 9 others, , 14 Nov 2017, In: eLife. 6, 21 p., e30247.Research output: Contribution to journal › Article › peer-review
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Enzymatic and Chemoenzymatic Three-Step Cascades for the Synthesis of Stereochemically Complementary Trisubstituted Tetrahydroisoquinolines
Erdmann, V., Lichman, B. R., Zhao, J., Simon, R. C., Kroutil, W., Ward, J. M., Hailes, H. C. & Rother, D., 2 Oct 2017, In: Angewandte Chemie - International Edition. 56, 41, p. 12503-12507 5 p.Research output: Contribution to journal › Article › peer-review
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Enzyme catalysed Pictet-Spengler formation of chiral 1,1'-disubstituted- and spiro-tetrahydroisoquinolines
Lichman, B. R., Zhao, J., Hailes, H. C. & Ward, J. M., 3 Apr 2017, In: Nature Communications. 8, 9 p., 14883.Research output: Contribution to journal › Article › peer-review
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Structural Evidence for the Dopamine-First Mechanism of Norcoclaurine Synthase
Lichman, B. R., Sula, A., Pesnot, T., Hailes, H. C., Ward, J. M. & Keep, N. H., 10 Oct 2017, In: Biochemistry. 56, 40, p. 5274-5277 4 p.Research output: Contribution to journal › Article › peer-review
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2015
Dopamine-first mechanism enables the rational engineering of the norcoclaurine synthase aldehyde activity profile
Lichman, B. R., Gershater, M. C., Lamming, E. D., Pesnot, T., Sula, A., Keep, N. H., Hailes, H. C. & Ward, J. M., 24 Jan 2015, In: FEBS Journal. 282, 6, p. 1137-1151 15 p.Research output: Contribution to journal › Article › peer-review
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One-pot triangular chemoenzymatic cascades for the syntheses of chiral alkaloids from dopamine
Lichman, B. R., Lamming, E. D., Pesnot, T., Smith, J. M., Hailes, H. C. & Ward, J. M., 1 Feb 2015, In: Green Chemistry. 17, 2, p. 852-855 4 p.Research output: Contribution to journal › Article › peer-review
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2014
The folding of a family of three-helix bundle proteins: Spectrin R15 has a robust folding nucleus, unlike its homologous neighbours
Kwa, L. G., Wensley, B. G., Alexander, C. G., Browning, S. J., Lichman, B. R. & Clarke, J., 3 Apr 2014, In: Journal of Molecular Biology. 426, 7, p. 1600-1610 11 p.Research output: Contribution to journal › Article › peer-review
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2011
Identification of adult nephron progenitors capable of kidney regeneration in zebrafish
Diep, C. Q., Ma, D., Deo, R. C., Holm, T. M., Naylor, R. W., Arora, N., Wingert, R. A., Bollig, F., Djordjevic, G., Lichman, B., Zhu, H., Ikenaga, T., Ono, F., Englert, C., Cowan, C. A., Hukriede, N. A., Handin, R. I. & Davidson, A. J., 3 Feb 2011, In: Nature. 470, 7332, p. 95-101 7 p.Research output: Contribution to journal › Article › peer-review