Research output per year
Research output per year
- 38 results
Search results
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2023
Myofibrillar myopathy hallmarks associated with ZAK deficiency
Stonadge, A., Genzor, A. V., Russell, A., Hamed, M. F., Romero, N., Evans, G., Pownall, B., Bekker-Jensen, S. & Blanco, G., 1 Sept 2023, In: Human Molecular Genetics. 32, 17, p. 2751-2770 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development
Cowell, L., King, M., West, H., Broadsmith, M., Genever, P., Pownall, B. & Isaacs, H. V., 19 Oct 2023, In: PLoS ONE. 18, 10, 24 p., e0286040.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
ROS-induced ribosome impairment underlies ZAKa-mediated metabolic decline in obesity and aging
Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M. & Willis, A. E. & 10 others, , 8 Dec 2023, In: Science. 382, 6675, 15 p., 1135.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The Presence of Two MyoD Genes in a Subset of Acanthopterygii Fish Is Associated with a Polyserine Insert in MyoD1
White, L. J., Russell, A. J., Pizzey, A. R., Dasmahapatra, K. K. & Pownall, M. E., 28 Apr 2023, In: Journal of developmental biology. 11, 2, 14 p., 19.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2022
Two closely related ureotelic fish species of the genus Alcolapia express different levels of ammonium transporters in gills
White, L. J., Rose, M., Lawson, M., Joyce, D., Smith, A. M., Thomas, G. H., Dasmahapatra, K. K. & Pownall, M. E., 1 Nov 2022, In: Biology Open. 11, 11, 10 p., bio059575.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2020
Adaptation of the carbamoyl-phosphate synthetase (CPS) enzyme in an extremophile fish
White, L., Sutton, G., Shechonge, A., Day, J., Dasmahapatra, K. K. & Pownall, B., 14 Oct 2020, (E-pub ahead of print) In: Royal Society Open Science. 7, 10, 201200.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Exploring the Expression of Cardiac Regulators in a Vertebrate Extremophile: The Cichlid Fish Oreochromis (Alcolapia) alcalica
Sutton, G., White, L., Ford, A. G. P., Shechonge, A., Day, J. J., Dasmahapatra, K. K. & Pownall, M. E., 4 Oct 2020, In: J Dev Biol. 8, 4, 19 p., 22.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Machine learning discriminates a movement disorder in a zebrafish model of Parkinson's disease
Hughes, G., Lones, M., M, B., Currie, P., Smith, S. L. & Pownall, M. E., 16 Oct 2020, In: Disease Models & Mechanisms. 13, 10, 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2019
Skeletal muscle differentiation drives a dramatic downregulation of RNA polymerase III activity and differential expression of Polr3g isoforms
McQueen, C., Hughes, G. L. & Pownall, M. E., 1 Oct 2019, In: Developmental Biology. 454, 1, 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Xenopus laevis FGF16 activates the expression of genes coding for the transcription factors Sp5 and Sp5l
Elsy, M., Rowbotham, A., Lord, H., Isaacs, H. V. & Pownall, M. E., 1 Nov 2019, (E-pub ahead of print) In: International Journal of Developmental Biology. 63 , 11/12, p. 1-10 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2018
Transcriptional up-regulation of BAG3, a Chaperone Assisted Selective Autophagy factor, in animal models of KY-deficient hereditary myopathy
Jokl, E. J., Hughes, G. L., Cracknell, T. R., Pownall, M. E. & Blanco, G., 18 Jun 2018, In: Disease Models & Mechanisms. 38 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2017
An analysis of MyoD-dependent transcription using CRISPR/Cas9 gene targeting in Xenopus tropicalis embryos
Pownall, M. E. & McQueen, C., 15 Aug 2017, In: Mechanisms of development. 146, 1, p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
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2016
Regulation of Hedgehog Signalling Inside and Outside the Cell
Ramsbottom, S. A. & Pownall, M. E., 20 Jul 2016, In: Journal of developmental biology. 4, 3, p. 23 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2015
Computational approaches for understanding the diagnosis and treatment of Parkinson's disease
Smith, S. L., Lones, M. A., Bedder, M., Alty, J. E., Cosgrove, J., Maguire, R. J., Pownall, M. E., Ivanoiu, D., Lyle, C., Cording, A. & Elliott, C. J. H., Dec 2015, In: IET Systems Biology. 9, 6, p. 226-233 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Sulf1 has ligand-dependent effects on canonical and non-canonical Wnt signalling
Fellgett, S. W., Maguire, R. J. & Pownall, M. E., 1 Apr 2015, In: Journal of Cell Science. 128, 7, p. 1408-1421 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients
Fellgett, S. W., Ramsbottom, S. A., Maguire, R. J., Cross, S., O'Toole, P. & Pownall, M. E., 14 Dec 2015, In: Journal of Visualized Experiments. 106, e53162.Research output: Contribution to journal › Article › peer-review
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2014
Sulf1 influences the Shh morphogen gradient during the dorsal ventral patterning of the neural tube in Xenopus tropicalis
Ramsbottom, S. A., Maguire, R. J., Fellgett, S. W. & Pownall, M. E., 15 Jul 2014, In: Developmental Biology. 391, 2, p. 207-218 12 p.Research output: Contribution to journal › Article › peer-review
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Wnt-dependent osteogenic commitment of bone marrow stromal cells using a novel GSK3β inhibitor
Cook, D. A., Fellgett, S. W., Pownall, M. E., O'Shea, P. J. & Genever, P. G., 1 Mar 2014, In: Stem Cell Research. 12, 2, p. 415-427Research output: Contribution to journal › Article › peer-review
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2013
Sulf1 modulates BMP signaling and is required for somite morphogenesis and development of the horizontal myoseptum
Meyers, J., Planamento, J., Ebrom, P., Krulewitz, N., Wade, E. & Pownall, M. E., 15 Jun 2013, In: Developmental Biology. 378, 2, p. 107-121 15 p.Research output: Contribution to journal › Article › peer-review
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2012
Early transcriptional targets of MyoD link myogenesis and somitogenesis
Maguire, R. J., Isaacs, H. V. & Pownall, M. E., 15 Nov 2012, In: Developmental Biology. 371, 2, p. 256-268 13 p.Research output: Contribution to journal › Article › peer-review
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2011
Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells
Munkley, J., Copeland, N. A., Moignard, V., Knight, J., Greaves, E., Ramsbottom, S. A., Pownall, B., Southgate, J., Ainscough, J. & Coverley, D. A., Apr 2011, In: Nucleic Acids Research. 39, 7, p. 2671-2677 7 p., PMID: 21109536.Research output: Contribution to journal › Article › peer-review
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2010
Neural crest migration requires the activity of the extracellular sulphatases XtSulf1 and XtSulf2
Guiral, E. C., Faas, L. & Pownall, M. E., 15 May 2010, In: Developmental Biology. 341, 2, p. 375-388 14 p.Research output: Contribution to journal › Article › peer-review
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2009
A role for XtSulf1 in germ cell migration
Bland, N. & Pownall, M. E., Aug 2009, In: Mechanisms of development. 126, p. S311-S311 1 p.Research output: Contribution to journal › Article › peer-review
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Characterisation of the Fibroblast Growth Factor Dependent Transcriptome in Early Development
Branney, P. A., Faas, L., Steane, S. E., Pownall, M. E. & Isaacs, H. V., 31 Mar 2009, In: PLoS ONE. 4, 3, p. 1-17 17 p., e4951.Research output: Contribution to journal › Article › peer-review
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Complementary expression of HSPG 6-O-endosulfatases and 6-O-sulfotransferase in the hindbrain of Xenopus laevis
Winterbottom, E. F. & Pownall, M. E., Mar 2009, In: Gene expression patterns. 9, 3, p. 166-172 7 p.Research output: Contribution to journal › Article › peer-review
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FGF signalling modulates transcriptional repression by Xenopus groucho-related-4
Burks, P. J., Isaacs, H. V. & Pownall, M. E., May 2009, In: Biology of the Cell. 101, 5, p. 301-308 8 p.Research output: Contribution to journal › Article › peer-review
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Myf-5 and the molecular analysis of tail development in the four-toed salamander, Hemidactylium scutatum
Hurney, C. A., Lee, A. D., Konen, L. M. & Pownall, M. E., 15 Jul 2009, In: Developmental Biology. 331, 2, p. 464-464 1 p.Research output: Contribution to journal › Article › peer-review
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The role of Sulf1 in Sonic hedgehog mediated neuronal patterning
Ramsbottom, S. & Pownall, M., Aug 2009, In: Mechanisms of development. 126, p. S322-S322 1 p.Research output: Contribution to journal › Article › peer-review
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2008
Extracellular regulation of developmental cell signaling by XtSulf1
Freeman, S. D., Moore, W. M., Guiral, E. C., Holme, A. D., Turnbull, J. E. & Pownall, M. E., 15 Aug 2008, In: Developmental Biology. 320, 2, p. 436-445 10 p.Research output: Contribution to journal › Article › peer-review
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2007
FGF4 regulates blood and muscle specification in Xenopus laevis
Isaacs, H. V., Deconinck, A. E. & Pownall, M. E., 8 Nov 2007, In: Biology of the Cell. 99, 3, p. 165-173 8 p.Research output: Contribution to journal › Article › peer-review
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Molecular characterisation of a candidate gut sucrase in the pea aphid, Acyrthosiphon pisum
Price, D. R. G., Karley, A. J., Ashford, D. A., Isaacs, H. V., Pownall, M. E., Wilkinson, H. S., Gatehouse, J. A. & Douglas, A. E., Apr 2007, In: Insect Biochemistry and Molecular Biology. 37, 4, p. 307-317 11 p.Research output: Contribution to journal › Article › peer-review
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2006
Expression of enzymes involved in thyroid hormone metabolism during the early development of Xenopus tropicalis
Tindall, A. J., Morris, I. D., Pownall, M. E. & Isaacs, H. V., Oct 2006, In: Biology of the Cell. 99, 3, p. 151-163 12 p.Research output: Contribution to journal › Article › peer-review
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2005
A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter
Reece-Hoyes, J. S., Pownall, M. E., Isaacs, H. V. & Keenan, I. D., 15 Jun 2005, In: Developmental Biology. 282, 2, p. 509-523 14 p.Research output: Contribution to journal › Article › peer-review
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Xenopus tropicalis peroxidasin gene is expressed within the developing neural tube and pronephric kidney
Tindall, A. J., Pownall, M. E., Morris, I. D. & Isaacs, H. V., Feb 2005, In: Developmental Dynamics. 232, 2, p. 377-384 8 p.Research output: Contribution to journal › Article › peer-review
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2004
Hedgehog regulation of superficial slow muscle fibres in Xenopus and the evolution of tetrapod trunk myogenesis
Grimaldi, A., Tettamanti, G., Martin, B. L., Gaffield, W., Pownall, M. E. & Hughes, S. M., Jul 2004, In: Development. 131, 14, p. 3249-3262 14 p.Research output: Contribution to journal › Article › peer-review
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QSulf1, a heparan sulfate 6-O-endosulfatase, inhibits fibroblast growth factor signaling in mesoderm induction and angiogenesis
Wang, S., Ai, X., Freeman, S. D., Pownall, M. E., Lu, Q., Kessler, D. S. & Emerson, C. P., 2004, In: Proceedings of the National Academy of Sciences of the United States of America. 101, 14, p. 4833-4838 5 p.Research output: Contribution to journal › Article › peer-review
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2003
An inducible system for the study of FGF signalling in early amphibian development
Pownall, M. E., Welm, B. E., Freeman, K. W., Spencer, D. M., Rosen, J. M. & Isaacs, H. V., 1 Apr 2003, In: Developmental Biology. 256, 1, p. 89-99 10 p.Research output: Contribution to journal › Article › peer-review
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2002
eFGF is required for the activation of XmyoD in the myogenic cell lineage of Xenopus laevis
Fisher, M. E., Isaacs, H. V. & Pownall, M. E., 15 Mar 2002, In: Development. 129, 6, p. 1307-1315 8 p.Research output: Contribution to journal › Article › peer-review