Elaine Brown

Search results

• 2020

  Essential roles for deubiquitination in Leishmania life cycle progression

  Damianou, A., Burge, R., Catta-Preta, C. M. C., Geoghegan, V. L., Nievas, R., Newling, K., Brown, E., Burchmore, R. J., Rodenko, B. & Mottram, J. C., 9 Jun 2020, (Accepted/In press) In: PLOS PATHOGENS.

  Research output: Contribution to journal › Article › peer-review

  File

• Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

  Saldivia Concepcion, M. A., Fang, E., Ma, X., Myburgh, E., Brambilla Carnielli Trindade, J., Bower-Lepts, C., Brown, E., Ritchie, R., Lakshminarayana, S. B., Chen, Y-L., Patra, D., Ornelas, E., Koh, H. X. Y., Williams, S., Supek, F., Paape, D., McCulloch, R., Kaiser, M., Barrett, M. P., Jiricek, J., & 3 othersDiagana, T. T., Mottram, J. C. & Rao, S. P. S., Oct 2020, In: Nature Microbiology. 5, p. 1207-1216

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2019

  Evaluation of Clan CD C11 peptidase PNT1 and other Leishmania mexicana cysteine peptidases as potential drug targets

  Grewal, J., Catta Preta, C., Brown, E., Anand, J. & Mottram, J. C., 1 Nov 2019, In: BIOCHIMIE. 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2018

  A Leishmania infantum genetic marker associated with miltefosine treatment failure for visceral leishmaniasis

  Mottram, J. C., Jeffares, D., Brambilla Carnielli Trindade, J., Crouch, K., Forrester, S. J., Costa Silva, V., Carvalho, S. F. G., Damasceno, J. D., Brown, E., Dickens, N. J., Costa, D. L., Costa, C. H. N. & Dietze, R., 27 Sept 2018, In: EBioMedicine. 36, 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2016

  Conditional gene deletion with DiCre demonstrates an essential role for CRK3 in Leishmania mexicana cell cycle regulation

  Duncan, S. M., Myburgh, E., Philipon, C., Brown, E., Meissner, M., Brewer, J. & Mottram, J. C., 16 Mar 2016, (E-pub ahead of print) In: Molecular Microbiology. 100, 6, p. 931-944 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• PNT1 is a C11 Cysteine Peptidase Essential for Replication of the Trypanosome Kinetoplast.

  Grewal, J., McLuskey, K., Das, D., Myburgh, E., Wilkes, J., Brown, E., Lemgruber, L., Gould, M. K., Burchmore, R. J., Coombs, G. H., Schnaufer, A. & Mottram, J. C., 29 Apr 2016, In: Journal of Biological Chemistry. 291, 18, p. 9492-9500 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2014

  Regulators of Trypanosoma brucei Cell Cycle Progression and Differentiation Identified Using a Kinome-Wide RNAi Screen

  Jones, N. G., Thomas, E. B., Brown, E., Dickens, N. J., Hammarton, T. C. & Mottram, J. C., 16 Jan 2014, In: PLOS PATHOGENS. 10, 1, 16 p., e1003886.

  Research output: Contribution to journal › Article › peer-review

  Open Access