Gideon James Grogan

Gideon James Grogan

Prof

Former affiliations

Accepting PhD Students

PhD projects

New PhD projects for Oct 2024 will be announced in Autumn 2023

Personal profile

Research interests

Structure, Function and Application of Novel Biocatalysts

  • Organic Chemistry - Synthesis and analysis of biotransformation substrates and product standards.
  • Microbiology - Screening for new microbial transformations; optimisation of biocatalyst production.
  • Molecular biology - Cloning, expression and manipulation of novel genes of interest.
  • Structural biology - Investigation and tailoring of enzyme structure and function

We are currently studying a variety of novel enzymatic systems including:

  • Carbon-carbon bond lyases and hydrolases
  • Enzymatic transformation of substrates containing silicon
  • Cytochromes P450 and Flavin-dependent oxidases
  • Comparative structural biology of enzyme superfamilies (Dehydrogenases, Oxidases)

Close collaboration between the YSBL group and Chemistry Department at the University of York ensures that facilities are available for all aspects of research into this area of chemical biology, from organic synthesis and analysis through to protein structure studies.

Collaborations and top research areas from the last five years

Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
  • Sequence and HMM libraries

    Elisée, E. (Creator), Ducrot, L. (Creator), Méheust, R. (Creator), Bastard, K. (Creator), Fossey-Jouenne, A. (Creator), Pelletier, E. (Creator), Petit, J. L. (Creator), Stam, M. (Creator), Grogan, G. J. (Creator), Berardinis, V. D. (Creator), Zaparucha, A. (Creator), Vallenet, D. (Creator) & Vergne-Vaxelaire, C. (Creator), Zenodo, 12 Sept 2023

    Dataset