Gideon John Davies, FRS, FMedSci

Search results

• 2001

  Three-dimensional structures of UDP-sugar glycosyltransferases illuminate the biosynthesis of plant polysaccharides

  Charnock, S. J., Henrissat, B. & Davies, G. J., Feb 2001, In: Plant Physiology. 125, 2, p. 527-531 5 p.

  Research output: Contribution to journal › Letter › peer-review

• 2000

  A new variant of the Ntn hydrolase fold revealed by the crystal structure of L-aminopeptidase D-Ala-esterase/amidase from Ochrobactrum anthropi

  Bompard-Gilles, C., Villeret, V., Davies, G. J., Fanuel, L., Joris, B., Frere, J. M. & Van Beeumen, J., 15 Feb 2000, In: Structure. 8, 2, p. 153-162 10 p.

  Research output: Contribution to journal › Article › peer-review

• Glycoside hydrolases and glycosyltransferases. Families, modules, and implications for genomics

  Henrissat, B. & Davies, G. J., Dec 2000, In: Plant Physiology. 124, 4, p. 1515-1519 5 p.

  Research output: Contribution to journal › Article › peer-review

• Highly efficient synthesis of beta(1 -> 4)-oligo- and -polysaccharides using a mutant cellulase

  Fort, S., Boyer, V., Greffe, L., Davies, G., Moroz, O., Christiansen, L., Schulein, M., Cottaz, S. & Driguez, H., 14 Jun 2000, In: Journal of the American Chemical Society. 122, 23, p. 5429-5437 9 p.

  Research output: Contribution to journal › Article › peer-review

• Insights into ligand-induced conformational change in Cel5A from Bacillus agaradhaerens revealed by a catalytically active crystal form

  Varrot, A., Schulein, M. & Davies, G. J., 31 Mar 2000, In: Journal of Molecular Biology. 297, 3, p. 819-828 10 p.

  Research output: Contribution to journal › Article › peer-review

• Structural analysis of a chimeric bacterial alpha-amylase: High-resolution analysis of native and ligand complexes

  Brzozowski, A. M., Lawson, D. M., Turkenburg, J. P., Bisgaard-Frantzen, H., Svendsen, A., Borchert, T. V., Dauter, Z., Wilson, K. S. & Davies, G. J., 8 Aug 2000, In: Biochemistry. 39, 31, p. 9099-9107 9 p.

  Research output: Contribution to journal › Article › peer-review

• Structural enzymology of enzymatic glycosyl transfer: Glycoside hydrolases, polysaccharide lyases, and glycosyltransferases.

  Davies, G. J., Charnock, S. J., Varrot, A. & Schulein, M., 15 Feb 2000, In: Biochemistry. 39, 6, p. 1543-1543 1 p.

  Research output: Contribution to journal › Article › peer-review

• Structure and function of Humicola insolens family 6 cellulases: Structure of the endoglucanase, Cel6B, at 1.6 Å resolution

  Davies, G. J., Marek Brzozowski, A., Dauter, M., Varrot, A. & Schülein, M., 15 May 2000, In: Biochemical journal. 348, 1, p. 201-207 7 p.

  Research output: Contribution to journal › Article › peer-review

• Structure and function of Humicola insolens family 6 cellulases: structure of the endoglucanase, Cel6B, at 1.6 angstrom resolution

  Davies, G. J., Brzozowski, A. M., Dauter, M., Varrot, A. & Schulein, M., 15 May 2000, In: Biochemical journal. 348, p. 201-207 7 p.

  Research output: Contribution to journal › Article › peer-review

• Substrate specificity in glycoside hydrolase family 10 - Structural and kinetic analysis of the streptomyces lividans xylanase 10A

  Ducros, V., Charnock, S. J., Derewenda, U., Derewenda, Z. S., Dauter, Z., Dupont, C., Shareck, F., Morosoli, R., Kluepfel, D. & Davies, G. J., 28 Jul 2000, In: Journal of Biological Chemistry. 275, 30, p. 23020-23026 7 p.

  Research output: Contribution to journal › Article › peer-review

• Substrate specificity in glycoside hydrolase family 10 - Tyrosine 87 and Leucine 314 play a pivotal, role in discriminating between glucose and xylose binding in the proximal active site of pseudomonas cellulosa xylanase 10A

  Andrews, S. R., Charnock, S. J., Lakey, J. H., Davies, G. J., Claeyssens, M., Nerinckx, W., Underwood, M., Sinnott, M. L., Warren, R. A. J. & Gilbert, H. J., 28 Jul 2000, In: Journal of Biological Chemistry. 275, 30, p. 23027-23033 7 p.

  Research output: Contribution to journal › Article › peer-review

• The X6 "thermostabilizing" domains of xylanases are carbohydrate-binding modules: Structure and biochemistry of the Clostridium thermocellum X6b domain

  Charnock, S. J., Bolam, D. N., Turkenburg, J. P., Gilbert, H. J., Ferreira, L. M. A., Davies, G. J. & Fontes, C. M. G. A., 2 May 2000, In: Biochemistry. 39, 17, p. 5013-5021 9 p.

  Research output: Contribution to journal › Article › peer-review

• 1999

  Catalysis and specificity in enzymatic glycoside hydrolysis: a B-2,B-5 conformation for the glycosyl-enzyme intermediate revealed by the structure of the Bacillus agaradhaerens family 11 xylanase

  Sabini, E., Sulzenbacher, G., Dauter, M., Dauter, Z., Jorgensen, P. L., Schulein, M., Dupont, C., Davies, G. J. & Wilson, K. S., Jul 1999, In: Chemistry & Biology. 6, 7, p. 483-492 10 p.

  Research output: Contribution to journal › Article › peer-review

• Cloning, crystallization and preliminary X-ray analysis of a nucleotide-diphospho-sugar transferase spsA from Bacillus subtilis

  Charnock, S. J. & Davies, G. J., Mar 1999, In: Acta Crystallographica. Section D, Biological Crystallography. 55, p. 677-678 2 p.

  Research output: Contribution to journal › Article › peer-review

• Crystallization and preliminary X-ray analysis of the 6-phospho-alpha-glucosidase from Bacillus subtilis

  Varrot, A., Yamamoto, H., Sekiguchi, J., Thompson, J. & Davies, G. J., Jun 1999, In: Acta Crystallographica. Section D, Biological Crystallography. 55, p. 1212-1214 3 p.

  Research output: Contribution to journal › Article › peer-review

• Crystallization and preliminary X-ray crystallographic analysis of a Trichoderma reesei beta-mannanase from glycoside hydrolase family 5

  Sabini, E., Brzozowski, A. M., Dauter, M., Davies, G. J., Wilson, K. S., Paloheimo, M., Suominen, P., Siika-Aho, M. & Penttila, M., May 1999, In: Acta Crystallographica. Section D, Biological Crystallography. 55, p. 1058-1060 3 p.

  Research output: Contribution to journal › Article › peer-review

• Crystal structure of the catalytic core domain of the family 6 cellobiohydrolase II, Cel6A, from Humicola insolens, at 1.92 angstrom resolution

  Varrot, A., Hastrup, S., Schulein, M. & Davies, G. J., 15 Jan 1999, In: Biochemical journal. 337, p. 297-304 8 p.

  Research output: Contribution to journal › Article › peer-review

• Lateral protonation of a glycosidase inhibitor. Structure of the Bacillus agaradhaerens Cel5A in complex with a cellobiose-derived imidazole at 0.97 angstrom resolution

  Varrot, A., Schulein, M., Pipelier, M., Vasella, A. & Davies, G. J., 24 Mar 1999, In: Journal of the American Chemical Society. 121, 11, p. 2621-2622 2 p.

  Research output: Contribution to journal › Article › peer-review

• Structural changes of the active site tunnel of Humicola insolens cellobiohydrolase, Cel6A, upon oligosaccharide binding

  Varrot, A., Schulein, M. & Davies, G. J., 13 Jul 1999, In: Biochemistry. 38, 28, p. 8884-8891 8 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the nucleotide-diphospho-sugar transferase, SpsA from Bacillus subtilis, in native and nucleotide-complexed forms

  Charnock, S. J. & Davies, G. J., 18 May 1999, In: Biochemistry. 38, 20, p. 6380-6385 6 p.

  Research output: Contribution to journal › Article › peer-review

• The crystal structure of a 2-fluorocellotriosyl complex of the Streptomyces lividans endoglucanase CelB2 at 1.2 angstrom resolution

  Sulzenbacher, G., Mackenzie, L. F., Wilson, K. S., Withers, S. G., Dupont, C. & Davies, G. J., 13 Apr 1999, In: Biochemistry. 38, 15, p. 4826-4833 8 p.

  Research output: Contribution to journal › Article › peer-review

• The structure of the exo-beta-(1,3)-glucanase from Candida albicans in native and bound forms: Relationship between a pocket and groove in family 5 glycosyl hydrolases

  Cutfield, S. M., Davies, G. J., Murshudov, G., Anderson, B. F., Moody, P. C. E., Sullivan, P. A. & Cutfield, J. F., 3 Dec 1999, In: Journal of Molecular Biology. 294, 3, p. 771-783 13 p.

  Research output: Contribution to journal › Article › peer-review

• Trapped in the act of catalysis

  Davies, G. J. & Wilson, K. S., May 1999, In: Nature Structural Biology. 6, 5, p. 406-408 3 p.

  Research output: Contribution to journal › Article › peer-review

• X-ray structure of Novamyl, the five-domain "maltogenic" alpha-amylase from Bacillus stearothermophilus: Maltose and acarbose complexes at 1.7 angstrom resolution

  Dauter, Z., Dauter, M., Brzozowski, A. M., Christensen, S., Borchert, T. V., Beier, L., Wilson, K. S. & Davies, G. J., 29 Jun 1999, In: Biochemistry. 38, 26, p. 8385-8392 8 p.

  Research output: Contribution to journal › Article › peer-review

• 1998

  Crystal structure of the family 7 endoglucanase I (Cel7B) from Humicola insolens at 2.2 angstrom resolution and identification of the catalytic nucleophile by trapping of the covalent glycosyl-enzyme intermediate

  Mackenzie, L. F., Sulzenbacher, G., Divne, C., Jones, T. A., Woldike, H. F., Schulein, M., Withers, S. G. & Davies, G. J., 15 Oct 1998, In: Biochemical journal. 335, p. 409-416 8 p.

  Research output: Contribution to journal › Article › peer-review

• Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 angstrom resolution

  Ducros, V., Brzozowski, A. M., Wilson, K. S., Brown, S. H., Ostergaard, P., Schneider, P., Yaver, D. S., Pedersen, A. H. & Davies, G. J., Apr 1998, In: Nature Structural Biology. 5, 4, p. 310-316 7 p.

  Research output: Contribution to journal › Article › peer-review

• Snapshots along an enzymatic reaction coordinate: Analysis of a retaining beta-glycoside hydrolase

  Davies, G. J., Mackenzie, L., Varrot, A., Dauter, M., Brzozowski, A. M., Schulein, M. & Withers, S. G., 25 Aug 1998, In: Biochemistry. 37, 34, p. 11707-11713 7 p.

  Research output: Contribution to journal › Article › peer-review

• Structural studies on cellulases

  Davies, G. J., May 1998, In: Biochemical Society transactions. 26, 2, p. 167-173 7 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the Bacillus agaradherans family 5 endoglucanase at 1.6 Å and its cellobiose complex at 2.0 Å resolution

  Davies, G. J., Dauter, M., Brzozowski, A. M., Bjørnvad, M. E., Andersen, K. V. & Schülein, M., 17 Feb 1998, In: Biochemistry. 37, 7, p. 1926-1932 7 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the Bacillus agaradherans family 5 endoglucanase at 1.6 angstrom and its cellobiose complex at 2.0 angstrom resolution

  Davies, G. J., Dauter, M., Brzozowski, A. M., Bjornvad, M. E., Andersen, K. V. & Schulein, M., 17 Feb 1998, In: Biochemistry. 37, 7, p. 1926-1932 7 p.

  Research output: Contribution to journal › Article › peer-review

• Validation tools: can they indicate the information content of macromolecular crystal structures?

  Dodson, E. J., Davies, G. J., Lamzin, V. S., Murshudov, G. N. & Wilson, K. S., 15 Jun 1998, In: Structure. 6, 6, p. 685-690 6 p.

  Research output: Contribution to journal › Article › peer-review

• 1997

  A classification of nucleotide-diphospho-sugar glycosyltransferases based on amino acid sequence similarities

  Campbell, J. A., Davies, G. J., Bulone, V. & Henrissat, B., 15 Sept 1997, In: Biochemical journal. 326, p. 929-939 11 p.

  Research output: Contribution to journal › Letter › peer-review

• Crystallization and preliminary X-ray analysis of the laccase from Coprinus cinereus

  Ducros, V., Davies, G. J., Lawson, D. M., Wilson, K. S., Brown, S. H., Ostergaard, P., Pedersen, A. H., Schneider, P., Yaver, D. S. & Brzozowski, A. M., 1 Sept 1997, In: Acta Crystallographica. Section D, Biological Crystallography. 53, p. 605-607 3 p.

  Research output: Contribution to journal › Article › peer-review

• Identification of the catalytic nucleophile of endoglucanase I from Fusarium oxysporum by mass spectrometry

  Mackenzie, L. F., Davies, G. J., Schulein, M. & Withers, S. G., 13 May 1997, In: Biochemistry. 36, 19, p. 5893-5901 9 p.

  Research output: Contribution to journal › Article › peer-review

• Nomenclature for sugar-binding subsites in glycosyl hydrolases

  Davies, G. J., Wilson, K. S. & Henrissat, B., 15 Jan 1997, In: Biochemical journal. 321, p. 557-559 3 p.

  Research output: Contribution to journal › Letter › peer-review

• Oligosaccharide specificity of a family 7 endoglucanase: insertion of potential sugar-binding subsites

  Davies, G. J., Ducros, V., Lewis, R. J., Borchert, T. V. & Schulein, M., 16 Sept 1997, In: JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY. 57, 1-3, p. 91-100 10 p.

  Research output: Contribution to journal › Article › peer-review

• Serratia marcescens chitobiase is a retaining glycosidase utilizing substrate acetamido group participation

  Drouillard, S., Armand, S., Davies, G. J., Vorgias, C. E. & Henrissat, B., 15 Dec 1997, In: Biochemical journal. 328, p. 945-949 5 p.

  Research output: Contribution to journal › Article › peer-review

• Structural and sequence-based classification of glycoside hydrolases

  Henrissat, B. & Davies, G., Oct 1997, In: CURRENT OPINION IN STRUCTURAL BIOLOGY. 7, 5, p. 637-644 8 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the Aspergillus oryzae alpha-amylase complexed with the inhibitor acarbose at 2.0 angstrom resolution

  Brzozowski, A. M. & Davies, G. J., 9 Sept 1997, In: Biochemistry. 36, 36, p. 10837-10845 9 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the Aspergillus oryzae α-amylase complexed with the inhibitor acarbose at 2.0 Å resolution

  Brzozowski, A. M. & Davies, G. J., 9 Sept 1997, In: Biochemistry. 36, 36, p. 10837-10845 9 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the endoglucanase I from Fusarium oxysporum: Native, cellobiose, and 3,4-epoxybutyl beta-D-cellobioside-inhibited forms, at 2.3 angstrom resolution

  Sulzenbacher, G., Schulein, M. & Davies, G. J., 13 May 1997, In: Biochemistry. 36, 19, p. 5902-5911 10 p.

  Research output: Contribution to journal › Article › peer-review

• The crystal structure of the catalytic core domain of endoglucanase I from Trichoderma reesei at 3.6 angstrom resolution, and a comparison with related enzymes

  Kleywegt, G. J., Zou, J. Y., Divne, C., Davies, G. J., Sinning, I., Stahlberg, J., Reinikainen, T., Srisodsuk, M., Teeri, T. T. & Jones, T. A., 26 Sept 1997, In: Journal of Molecular Biology. 272, 3, p. 383-397 15 p.

  Research output: Contribution to journal › Article › peer-review

• The Streptomyces lividans family 12 endoglucanase: Construction of the catalytic core, expression, and X-ray structure at 1.75 angstrom resolution

  Sulzenbacher, G., Shareck, F., Morosoli, R., Dupont, C. & Davies, G. J., 23 Dec 1997, In: Biochemistry. 36, 51, p. 16032-16039 8 p.

  Research output: Contribution to journal › Article › peer-review

• 1996

  Enzymatic ketonization of 2-hydroxymuconate: Specificity and mechanism investigated by the crystal structures of two isomerases

  Subramanya, H. S., Roper, D. I., Dauter, Z., Dodson, E. J., Davies, G. J., Wilson, K. S. & Wigley, D. B., 23 Jan 1996, In: Biochemistry. 35, 3, p. 792-802 11 p.

  Research output: Contribution to journal › Article › peer-review

• Structure and FTIR spectra of 3:2 complexes of trimethylamine N-oxide and 4-dimethylamine-2,6-dimethylpyridine N-oxide with perchloric acid

  Krzywda, S., Jaskolski, M., Gdaniec, M., DegaSzafran, Z., GrundwaldWyspianska, M., Szafran, M., Dauter, Z. & Davies, G., 10 Feb 1996, In: JOURNAL OF MOLECULAR STRUCTURE. 375, 3, p. 197-206 10 p.

  Research output: Contribution to journal › Article › peer-review

• Structure determination and refinement of the Humicola insolens endoglucanase V at 1.5 angstrom resolution

  Davies, G. J., Dodson, G., Moore, M. H., Tolley, S. P., Dauter, Z., Wilson, K. S., Rasmussen, G. & Schulein, M., 1 Jan 1996, In: Acta Crystallographica. Section D, Biological Crystallography. 52, p. 717 11 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the Fusarium oxysporum endoglucanase I with a nonhydrolyzable substrate analogue: Substrate distortion gives rise to the preferred axial orientation for the leaving group

  Sulzenbacher, G., Driguez, H., Henrissat, B., Schulein, M. & Davies, G. J., 3 Dec 1996, In: Biochemistry. 35, 48, p. 15280-15287 8 p.

  Research output: Contribution to journal › Article › peer-review

• The X-ray crystal structure of phosphomannose isomerase from Candida albicans at 1.7 angstrom resolution

  Cleasby, A., Wonacott, A., Skarzynski, T., Hubbard, R. E., Davies, G. J., Proudfoot, A. E. I., Bernard, A. R., Payton, M. A. & Wells, T. N. C., May 1996, In: Nature Structural Biology. 3, 5, p. 470-479 10 p.

  Research output: Contribution to journal › Article › peer-review

• 1995

  CONSERVED CATALYTIC MACHINERY AND THE PREDICTION OF A COMMON FOLD FOR SEVERAL FAMILIES OF GLYCOSYL HYDROLASES

  HENRISSAT, B., CALLEBAUT, I., FABREGA, S., LEHN, P., MORNON, J. P. & DAVIES, G., 18 Jul 1995, In: Proceedings of the National Academy of Sciences of the United States of America. 92, 15, p. 7090-7094 5 p.

  Research output: Contribution to journal › Article › peer-review

• CRYSTAL-STRUCTURE OF THE CATALYTIC DOMAIN OF A BACTERIAL CELLULASE BELONGING TO FAMILY-5

  DUCROS, V., CZJZEK, M., BELAICH, A., GAUDIN, C., FIEROBE, H. P., BELAICH, L. P., DAVIES, G. J. & HASER, R., 15 Sept 1995, In: Structure. 3, 9, p. 939-949 11 p.

  Research output: Contribution to journal › Article › peer-review