Harriet Chidwick

2024

Co-factor prosthesis facilitates biosynthesis of azido-pseudaminic acid probes for use as glycosyltransferase reporters

Keenan, T., Chidwick, H., Best, M., Flack, E., Yates, N., Hatton, N., Warnes, M. E. & Fascione, M. A., 2 Jan 2024, (Accepted/In press) In: Chemical communications.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Synthesis and screening of a library of Lewisx deoxyfluoro-analogues reveals differential recognition by glycan-binding partners

Hollingsworth, K., Di Maio, A., Richards, S-J., Vendeville, J-B., Wheatley, D. E., Council, C. E., Keenan, T., Chidwick, H., Huang, K., Parmeggiani, F., Marchesi, A., Chai, W., McBerney, R., Kaminski, T., Balmforth, M., Tamasanu, A., Finnigan, J., Young, C., Warriner, S., Webb, M. E., & 8 othersFascione, M. A., Flitsch, S. L., Galan, M. C., Feizi, T., Gibson, M. I., Liu, Y., Turnbull, W. B. & Linclau, B., 13 Sept 2024, In: Nature Communications. 15, 14 p., 7925.

Research output: Contribution to journal › Article › peer-review

Open Access

File

The Retaining Pse5Ac7Ac Pseudaminyltransferase KpsS1 Defines a Previously Unreported Glycosyltransferase Family (GT118)

Walklett, A., Flack, E., Chidwick, H., Hatton, N., Keenan, T., Budhadev, D., Walton, J., Thomas, G. H. & Fascione, M. A., 1 Feb 2024, (E-pub ahead of print) In: Angewandte Chemie International Edition. 7 p., e202318523.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2021

Reconstitution and optimisation of the biosynthesis of bacterial sugar pseudaminic acid (Pse5Ac7Ac) enables preparative enzymatic synthesis of CMP-Pse5Ac7Ac

Chidwick, H., Flack, E., Keenan, T., Walton, J., Thomas, G. H. & Fascione, M. A., 26 Feb 2021, In: Scientific Reports. 11, 12 p., 4756.

Research output: Contribution to journal › Article › peer-review

Open Access

File

2020

Biocatalytic Transfer of Pseudaminic Acid (Pse5Ac7Ac) Using Promiscuous Sialyltransferases in a Chemoenzymatic Approach to Pse5Ac7Ac Containing Glycosides

Flack, E., Chidwick, H., Guchhait, G., Keenan, T., Budhadev, D., Huang, K., Both, P., Mas Pons, J., Ledru, H., Rui, S., Stafford, G., Shaw, J., Galan, M. C., Flitsch, S. L., Thomas, G. H. & Fascione, M. A., 21 Aug 2020, (E-pub ahead of print) In: ACS Catalysis. 10, p. 9986-9993 8 p.

Research output: Contribution to journal › Article › peer-review

Open Access

File

Chemoenzymatic synthesis of 3-deoxy-3-fluoro-L-fucose and its enzymatic incorporation into glycoconjugates

Valverde, P., Vendeville, J-B., Hollingsworth, K., Mattey, A. P., Keenan, T., Chidwick, H., Ledru, H., Huonnic, K., Light, M. E., Turner, N., Jimenez Barbero, J., Galan, M. C., Fascione, M. A., Flitsch, S., Turnbull, W. B. & Linclau, B., 29 Apr 2020, (E-pub ahead of print) In: Chemical Communications. 5

Research output: Contribution to journal › Article › peer-review

Open Access

File

Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands

Richards, S-J., Keenan, T., Vendeville, J-B., Wheatley, D. E., Chidwick, H., Budhadev, D., Council, C. E., Webster, C. S., Ledru, H., Baker, A. N., Walker, M., Galan, M. C., Linclau, B., Fascione, M. A. & Gibson, M. I., 16 Nov 2020, In: Chemical Science.

Research output: Contribution to journal › Article › peer-review

Open Access

File