Harry Victor Isaacs

Search results

• 2023

  Regulation of gene expression downstream of a novel Fgf/Erk pathway during Xenopus development

  Cowell, L., King, M., West, H., Broadsmith, M., Genever, P., Pownall, B. & Isaacs, H. V., 19 Oct 2023, In: PLoS ONE. 18, 10, 24 p., e0286040.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2020

  A comparative analysis of fibroblast growth factor receptor signalling during Xenopus development

  Isaacs, H. V. & Brunsdon, H. R., 17 Feb 2020, (E-pub ahead of print) In: Biology of the Cell. 112, p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2019

  Xenopus laevis FGF16 activates the expression of genes coding for the transcription factors Sp5 and Sp5l

  Elsy, M., Rowbotham, A., Lord, H., Isaacs, H. V. & Pownall, M. E., 1 Nov 2019, (E-pub ahead of print) In: International Journal of Developmental Biology. 63 , 11/12, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2017

  N1-Src kinase is required for primary neurogenesis in Xenopus tropicalis

  Lewis, P. A., Bradley, I. C., Pizzey, A. R., Isaacs, H. V. & Evans, G. J. O., 30 Aug 2017, In: Journal of neuroscience. 37, 35, p. 8477-8584 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2016

  Human Lin28 forms a high-affinity 1:1 complex with the 106~363 cluster miRNA miR-363

  Peters, D. T., Fung, H. K., Levdikov, V. M., Irmscher, T., Warrander, F. C., Greive, S. J., Kovalevskiy, O., Isaacs, H. V., Coles, M. C. & Antson, A. A., 25 Aug 2016, In: Biochemistry. 55, p. 5021−5027 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2015

  Cdx ParaHox genes acquired distinct developmental roles after gene duplication in vertebrate evolution

  Marlétaz, F., Maeso, I., Faas, L., Isaacs, H. V. & Holland, P. W. H., 1 Aug 2015, In: BMC Biology. 13, p. 56 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• lin28 proteins promote expression of 17∼92 family miRNAs during amphibian development

  Warrander, F., Faas, L., Kovalevskiy, O., Peters, D., Coles, M., Antson, A. A., Genever, P. & Isaacs, H. V., 8 Oct 2015, In: Developmental Dynamics. 50 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2014

  An essential role for LPA signalling in telencephalon development

  Geach, T. J., Faas, L., Devader, C., Gonzalez-Cordero, A., Brunsdon, H., tabler, J., Isaacs, H. V. & Dale, L., Feb 2014, In: Development. 141, 4, p. 940-949 10 p., 104901.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2013

  Lin28 proteins are required for germ layer specification in Xenopus

  Faas, L., Warrander, F. C., Maguire, R., Ramsbottom, S., Quinn, D., Genever, P. & Isaacs, H. V., 1 Mar 2013, In: Development. 140, 5, p. 976-986 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2012

  Early transcriptionaltargetsofMyoDlinkmyogenesisandsomitogenesis

  Maguire, R. & Isaacs, H. V., 2012, (Accepted/In press) In: Developmental Biology.

  Research output: Contribution to journal › Article › peer-review

• Early transcriptional targets of MyoD link myogenesis and somitogenesis

  Maguire, R. J., Isaacs, H. V. & Pownall, M. E., 15 Nov 2012, In: Developmental Biology. 371, 2, p. 256-268 13 p.

  Research output: Contribution to journal › Article › peer-review
• 2011

  Gsx transcription factors repress Iroquois gene expression

  Winterbottom, E. F., Ramsbottom, S. A. & Isaacs, H. V., Jun 2011, In: Developmental dynamics : an official publication of the American Association of Anatomists. 240, 6, p. 1422-9 8 p.

  Research output: Contribution to journal › Article › peer-review
• 2010

  Conserved and novel roles for the Gsh2 transcription factor in primary neurogenesis

  Winterbottom, E. F., Illes, J. C., Faas, L. & Isaacs, H. V., 15 Aug 2010, In: Development. 137, 16, p. 2623-2631 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2009

  A water-specific aquaporin involved in aphid osmoregulation

  Shakesby, A. J., Wallace, I. S., Isaacs, H. V., Pritchard, J., Roberts, D. M. & Douglas, A. E., Jan 2009, In: Insect Biochemistry and Molecular Biology. 39, 1, p. 110 10 p.

  Research output: Contribution to journal › Article › peer-review

• Characterisation of the Fibroblast Growth Factor Dependent Transcriptome in Early Development

  Branney, P. A., Faas, L., Steane, S. E., Pownall, M. E. & Isaacs, H. V., 31 Mar 2009, In: PLoS ONE. 4, 3, p. 1-17 17 p., e4951.

  Research output: Contribution to journal › Article › peer-review

• Cloning and Expression Analysis of the Anterior ParaHox Genes, Gsh1 and Gsh2 From Xenopus tropicalis

  Illes, J. C., Winterbottom, E. & Isaacs, H. V., Jan 2009, In: Developmental Dynamics. 238, 1, p. 194-203 10 p.

  Research output: Contribution to journal › Article › peer-review

• FGF signalling modulates transcriptional repression by Xenopus groucho-related-4

  Burks, P. J., Isaacs, H. V. & Pownall, M. E., May 2009, In: Biology of the Cell. 101, 5, p. 301-308 8 p.

  Research output: Contribution to journal › Article › peer-review

• Functional analysis of the RNA binding protein lin-28 in Xenopus tropicalis

  Warrander, F., Faas, L. & Isaacs, H. V., Aug 2009, In: Mechanisms of development. 126, p. S233-S234 2 p.

  Research output: Contribution to journal › Article › peer-review

• Investigating the function of Gsx genes in Xenopus primary neurogenesis

  Winterbottom, E. & Isaacs, H., Aug 2009, In: Mechanisms of development. 126, p. S256-S256 1 p.

  Research output: Contribution to journal › Article › peer-review

• Overlapping Functions of Cdx1, Cdx2, and Cdx4 in the Development of the Amphibian Xenopus tropicalis

  Faas, L. & Isaacs, H. V., Apr 2009, In: Developmental Dynamics. 238, 4, p. 835-852 18 p.

  Research output: Contribution to journal › Article › peer-review
• 2007

  FGF4 regulates blood and muscle specification in Xenopus laevis

  Isaacs, H. V., Deconinck, A. E. & Pownall, M. E., 8 Nov 2007, In: Biology of the Cell. 99, 3, p. 165-173 8 p.

  Research output: Contribution to journal › Article › peer-review

• Molecular characterisation of a candidate gut sucrase in the pea aphid, Acyrthosiphon pisum

  Price, D. R. G., Karley, A. J., Ashford, D. A., Isaacs, H. V., Pownall, M. E., Wilkinson, H. S., Gatehouse, J. A. & Douglas, A. E., Apr 2007, In: Insect Biochemistry and Molecular Biology. 37, 4, p. 307-317 11 p.

  Research output: Contribution to journal › Article › peer-review

• Patterns of gene expression in schistosomes: localization by whole mount in situ hybridization

  Dillon, G. P., Illesh, J. C., Isaacs, H. V. & Wilson, R. A., Oct 2007, In: Parasitology. 134, 11, p. 1589-1597 8 p.

  Research output: Contribution to journal › Article › peer-review

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• 2006

  Expression of enzymes involved in thyroid hormone metabolism during the early development of Xenopus tropicalis

  Tindall, A. J., Morris, I. D., Pownall, M. E. & Isaacs, H. V., Oct 2006, In: Biology of the Cell. 99, 3, p. 151-163 12 p.

  Research output: Contribution to journal › Article › peer-review

• FGF signal transduction and the regulation of Cdx gene expression

  Keenan, I. D., Sharrard, R. M. & Isaacs, H. V., 15 Nov 2006, In: Developmental Biology. 299, 2, p. 478-488 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2005

  A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter

  Reece-Hoyes, J. S., Pownall, M. E., Isaacs, H. V. & Keenan, I. D., 15 Jun 2005, In: Developmental Biology. 282, 2, p. 509-523 14 p.

  Research output: Contribution to journal › Article › peer-review

• Xenopus tropicalis ParaHox genes: Conserved roles in posterior development and neurogenesis.

  Isaacs, H. V., Illes, J. C. & Faas, L., 15 Jul 2005, In: Developmental Biology. 283, 2, p. 655-656 2 p.

  Research output: Contribution to journal › Article › peer-review

• Xenopus tropicalis peroxidasin gene is expressed within the developing neural tube and pronephric kidney

  Tindall, A. J., Pownall, M. E., Morris, I. D. & Isaacs, H. V., Feb 2005, In: Developmental Dynamics. 232, 2, p. 377-384 8 p.

  Research output: Contribution to journal › Article › peer-review
• 2003

  An inducible system for the study of FGF signalling in early amphibian development

  Pownall, M. E., Welm, B. E., Freeman, K. W., Spencer, D. M., Rosen, J. M. & Isaacs, H. V., 1 Apr 2003, In: Developmental Biology. 256, 1, p. 89-99 10 p.

  Research output: Contribution to journal › Article › peer-review

• A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor

  Yokota, C., Kofron, M., Zuck, M., Houston, D. W., Isaacs, H., Asashima, M., Wylie, C. C. & Heasman, J., May 2003, In: Development. 130, 10, p. 2199-2212 14 p.

  Research output: Contribution to journal › Article › peer-review
• 2002

  Cloning and expression of the Cdx family from the frog Xenopus tropicalis

  Reece-Hoyes, J. S., Keenan, L. D. & Isaacs, H. V., Jan 2002, In: Developmental Dynamics. 223, 1, p. 134-140 7 p.

  Research output: Contribution to journal › Article › peer-review

• eFGF is required for the activation of XmyoD in the myogenic cell lineage of Xenopus laevis

  Fisher, M. E., Isaacs, H. V. & Pownall, M. E., 15 Mar 2002, In: Development. 129, 6, p. 1307-1315 8 p.

  Research output: Contribution to journal › Article › peer-review

• 1999

  Anteroposterior patterning by mutual repression of orthodenticle and caudal-type transcription factors

  Isaacs, H. V., Andreazzoli, M. & Slack, J. M. W., 1999, In: Evolution & development. 1, 3, p. 143-152 10 p.

  Research output: Contribution to journal › Article › peer-review