Research output per year
Research output per year
Prof
Accepting PhD Students
Ian Graham’s interests include how plants make and breakdown various metabolites, how these processes are controlled and how they impact on plant growth. He has used biochemical genetics to dissect the main metabolic pathways controlling oil mobilisation in Arabidopsis seed and provided new insight into how a lipid based signal controls seed germination. He has used similar approaches to investigate the synthesis of bioactive compounds in two of the world’s major medicinal crops. This has led to new understanding of how genome rearrangement has shaped the evolution of plant metabolism. The discovery of a 10 gene cluster responsible for the production of the anti-cancer compound noscapine in opium poppy provided the tools for molecular breeding of new commercial varieties. The discovery of a novel P450 – oxidoreductase gene fusion described the last unknown step in synthesis of morphine and codeine. Characterisation and genetic mapping of traits responsible for production of artemisinin in Artemisia annua has enabled development of F1 hybrid seed that can deliver a robust source of this vital anti-malarial drug for the developing world.
Research output: Working paper › Preprint
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Lichman, B. R. (Principal investigator), Graham, I. A. (Co-investigator) & O'Toole, P. J. (Co-investigator)
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
1/04/25 → 31/03/30
Project: Research project (funded) › Research
Graham, I. A. (Principal investigator)
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
15/11/23 → 14/11/28
Project: Research project (funded) › Research
Graham, I. A. (Principal investigator)
1/10/21 → 30/12/28
Project: Research project (funded) › Research
Graham, I. A. (Trustee)
Activity: Membership › Board
Graham, I. A. (Advisor)
Activity: Participating in or organising an event › Conference participation
Graham, I. A. (Chair)
Activity: Membership › Committee
Graham, I. A. (Supervisor), Catania, T. M. (Contributor) & Li, Y. (Contributor), National Center for Biotechnology Information (NCBI), 23 May 2022
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA770669 and one more link, https://www.ncbi.nlm.nih.gov/ (show fewer)
Dataset
Graham, I. A. (Supervisor), Czechowski, T. (Contributor) & Li, Y. (Contributor), National Library of Medicine, 25 Mar 2022
https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA819961
Dataset
Graham, I. A. (Recipient), 23 May 2016
Prize: Election to learned society
Graham, I. A. (Recipient), 28 Apr 2016
Prize: Election to learned society