Isabelle Pickles

Search results

• 2024

  Detection of sulfoquinovosidase activity in cell lysates using activity-based probes

  Li, Z., Pickles, I., Sharma, M., Melling, B., Pallasdies, L., Codée, J., Williams, S., Overkleeft, H. & Davies, G., 16 Apr 2024, (Accepted/In press) In: Angewandte Chemie International Edition. e202401358.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Epi-cyclophellitol cyclosulfate, a mechanism-based ER α-glucosidase II inhibitor, blocks replication of SARS-CoV-2 and other coronaviruses

  Thaler, M., Ofman, T. P., Kok, K., Heming, J. J. A., Moran, E., Pickles, I., Leijs, A. A., Nieuwendijk, A. M. C. H. V. D., Berg, R. J. B. H. N. V. D., Ruijgrok, G., Armstrong, Z., Salgado-Benvindo, C., Ninaber, D. K., Snijder, E. J., Boeckel, C. A. A. V., Artola, M., Davies, G. J., Overkleeft, H. S. & Hemert, M. J. V., 9 Jul 2024, (Accepted/In press) In: ACS Central Science.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Precision activity-based α-amylase probes for dissection and annotation of linear and branched-chain starch degrading enzymes

  Pickles, I. B., Chen, Y., Moroz, O., Brown, H. A., de Boer, C., Armstrong, Z., McGregor, N. G. S., Artola, M., Codée, J. D. C., Koropatkin, N. M., Overkleeft, H. S. & Davies, G. J., 27 Dec 2024, (E-pub ahead of print) In: Angewandte Chemie International Edition. 15 p., e202415219.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2023

  Widespread Family of NAD+-Dependent Sulfoquinovosidases at the Gateway to Sulfoquinovose Catabolism

  Kaur, A., Pickles, I. B., Sharma, M., Soler, N. M., Scott, N. E., Pidot, S. J., Goddard-Borger, E. D., Davies, G. J. & Williams, S. J., 15 Dec 2023, In: Journal of the American Chemical Society. 145, 51, p. 28216-28223 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File