Joana Raquel Correia Faria

Search results

• 2023

  An allele-selective inter-chromosomal protein bridge supports monogenic antigen expression in the African trypanosome

  Faria, J. R. C., Tinti, M., Marques, C. A., Zoltner, M., Yoshikawa, H., Field, M. C. & Horn, D., 11 Dec 2023, In: Nature Communications. 14, 1, 18 p., 8200.

  Research output: Contribution to journal › Article › peer-review

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• Competition among variants is predictable and contributes to the antigenic variation dynamics of African trypanosomes

  Escrivani, D. O., Scheidt, V., Tinti, M., Faria, J. & Horn, D., 3 Jul 2023, (Accepted/In press) In: PLOS PATHOGENS. 19, 7, e1011530.

  Research output: Contribution to journal › Article › peer-review

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• 2022

  CRISPR/Cas9-based precision tagging of essential genes in bloodstream form African trypanosomes

  Kovářová, J., Novotná, M., Faria, J., Rico, E., Wallace, C., Zoltner, M., Field, M. C. & Horn, D., May 2022, In: MOLECULAR AND BIOCHEMICAL PARASITOLOGY. 249, 7 p., 111476.

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• Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome

  Faria, J., Briggs, E. M., Black, J. A. & McCulloch, R., Dec 2022, In: Current Opinion in Microbiology . 70, p. 102209 13 p., 102209.

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• 2021

  Spatial integration of transcription and splicing in a dedicated compartment sustains monogenic antigen expression in African trypanosomes

  Faria, J., Luzak, V., Müller, L. S. M., Brink, B. G., Hutchinson, S., Glover, L., Horn, D. & Siegel, T. N., Mar 2021, In: Nature Microbiology. 6, 3, p. 289-300 12 p.

  Research output: Contribution to journal › Article › peer-review
• 2019

  Monoallelic expression and epigenetic memory sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

  Correia Faria, J. R., Glover, L., Hutchinson, S., Boehm, C., Field, M. C. & Horn, D., 9 Jul 2019, In: Nature Communications.

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• 2018

  Codon usage bias controls mRNA and protein abundance in the African trypanosome.

  Jeacock, L., Correia Faria, J. R. & Horn, D., 15 Mar 2018, In: eLife.

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• Gluconeogenesis using glycerol as a substrate in bloodstream-form Trypanosoma brucei.

  Kovarova, J., Nagar, R., Correia Faria, J. R., Ferguson, M. A. J., Barrett, M. P. & Horn, D., 27 Dec 2018, In: PLOS PATHOGENS.

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• Potential drug targets in the pentose phosphate pathway of trypanosomatids.

  Loureiro, I., Correia Faria, J. R., Santarem, N., Smith, T. K., Tavares, J. & Cordeiro-da-Silva, A., 2018, In: Current Medicinal Chemistry. 25, 39, p. 5239-5265 26 p.

  Research output: Contribution to journal › Article › peer-review

• The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1: implications to protein function and drug design.

  Ronan, C., Mendes Costa, D., Tavares, J., Correia Faria, J. R., Ciesielski, F., Ciapetti, P., Smith, T. K., MacDougall, J., Cordeiro-da-Silva, A. & Pemberton, I. K., 15 Mar 2018, In: PLoS ONE.

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• 2016

  Disclosing Ribose-5-Phosphate Isomerase B Essentiality in Trypanosomatids.

  Correia Faria, J. R., Loureiro, I., Santarem, N., Cecilio, P., Macedo Ribeiro, S., Tavares, J. & Cordeiro-da-Silva, A., 27 May 2016, In: Scientific Reports.

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• Leishmania infantum Asparagine Synthetase A Is Dispensable for Parasites Survival and Infectivity

  Correia Faria, J. R., Loureiro, I., Santarem, N., Macedo Ribeiro, S., Tavares, J. & Cordeiro-da-Silva, A., 15 Jan 2016, In: PLoS Neglected Tropical Diseases.

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• 2015

  Ribose-5-phosphate Isomerase B Knockdown Compromises Trypanosoma brucei Bloodstream Form Infectivity

  Loureiro, I., Correia Faria, J. R., Clayton, C., Macedo Ribeiro, S., Santarem, N., Roy, N., Cordeiro-da-Silva, A. & Tavares, J., 8 Jan 2015, In: PLoS Neglected Tropical Diseases.

  Research output: Contribution to journal › Article › peer-review

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• 2014

  Drug Discovery for Human African Trypanosomiasis: Identification of Novel Scaffolds by the Newly Developed HTS/Sybr Green Assay for Trypanosoma brucei.

  Correia Faria, J. R., Borsoi Moraes, C., Song, R., Pascoalino, B. S., Lee, N., Siqueira-Neto, J. L., M Cruz, D. J., Parkinson, T., Loset, J.-R., Cordeiro-da-Silva, A. & Freitas-Junior, L. H., 23 Nov 2014, In: Journal of biomolecular screening.

  Research output: Contribution to journal › Article › peer-review

  Open Access
• 2013

  Knockdown of Asparagine Synthetase A Renders Trypanosoma brucei Auxotrophic to Asparagine.

  Loureiro, I., Correia Faria, J. R., Clayton, C., Macedo Ribeiro, S., Roy, N., Santarem, N., Tavares, J. & Cordeiro-da-Silva, A., 5 Dec 2013, In: PLoS Neglected Tropical Diseases.

  Research output: Contribution to journal › Article › peer-review

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• 2012

  Phytochemical investigations and biological potential screening with cellular and non-cellular models of globe amaranth (Gomphrena globosaL.) inflorescences

  Silva, L. R., Valentão, P., Correia Faria, J. R., Ferreres, F., Sousa, C., Gil-Izquierdo, A., Pinho, B. R. & Andrade, P. B., 15 Nov 2012, In: Food Chemistry.

  Research output: Contribution to journal › Article › peer-review

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• 2010

  Exploiting Catharanthus roseus roots: Source of antioxidants

  Pereira, D. M., Correia Faria, J. R., Gaspar, L., Ferreres, F., Valentão, P., Sottomayor, M. & Andrade, P. B., 1 Jul 2010, In: Food Chemistry.

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• Pharmacological effects of Catharanthus roseus root alkaloids in acetylcholinesterase inhibition and cholinergic neurotransmission

  Pereira, D. M., Ferreres, F., Oliveira, J. M., Gaspar, L., Correia Faria, J. R., Valentão, P., Sottomayor, M. & Andrade, P. B., Jul 2010, In: Phytomedicine..

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• Simple and reproducible HPLC–DAD–ESI-MS/MS analysis of alkaloids in Catharanthus roseus roots

  Ferreres, F., Pereira, D. M., Valentão, P., Oliveira, J. M., Correia Faria, J. R., Gaspar, L., Sottomayor, M. & Andrade, P. B., 5 Jan 2010, In: Journal of pharmaceutical and biomedical analysis.

  Research output: Contribution to journal › Article › peer-review

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• 2009

  Boerhaavia diffusa: Metabolite profiling of a medicinal plant from Nyctaginaceae

  Pereira, D. M., Correia Faria, J. R., Gaspar, L., Valentão, P. & Andrade, P. B., Sept 2009, In: FOOD AND CHEMICAL TOXICOLOGY.

  Research output: Contribution to journal › Article › peer-review

  Open Access