Karl Philip Claxton

Search results

• 2024

  Achieving dynamic efficiency in pharmaceutical innovation: Identifying the optimal share of value and payments required

  Woods, B., Lomas, J., Sculpher, M., Weatherly, H. L. A. & Claxton, K. P., 2 Mar 2024, In: Health Economics. 33, 4, p. 804-819 16 p., hec.4795.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Apples and oranges

  Claxton, K., Lomas, J., Longo, F. & Salas Ortiz, A., 9 Mar 2024, (E-pub ahead of print) In: Health policy (Amsterdam, Netherlands). 143, p. 105041

  Research output: Contribution to journal › Article

• Rapid assessment of the need for evidence: applying the principles of value of information to research prioritisation

  Glynn, D., S. Gc, V., Claxton, K. P., Littlewood, C. & Rothery, C., 20 Jun 2024, (E-pub ahead of print) In: PharmacoEconomics.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Sampson and Cookson’s commentary: what is it good for?

  Claxton, K. P., Lomas, J., Longo, F. & Salas Ortiz, A., 1 Aug 2024, In: Health Policy. 146, p. 105100 3 p., 105100.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Social Decision-Making Analysis: A General Approach to Inform Decisions on Resources in the Public Sector

  Longo, F., Claxton, K. P., Griffin, S., Mason, A. R., Walker, S. M. & Weatherly, H. L. A., 29 Jan 2024, (Accepted/In press) In: Value in Health. 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Unpacking the care‐related quality of life effect of England's publicly funded adult social care. A panel data analysis

  Salas Ortiz, A., Longo, F., Claxton, K. P. & Lomas, J., 5 Oct 2024, (E-pub ahead of print) In: Health Economics. 21 p., hec.4907.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2023

  General Purpose Methods for Simulating Survival Data for Expected Value of Sample Information Calculations

  Vervaart, M., Aas, E., Claxton, K. P., Strong, M., Welton, N. J., Wisløff, T. & Heath, A., 27 Mar 2023, (E-pub ahead of print) In: Medical Decision Making. p. 272989X231162069

  Research output: Contribution to journal › Article › peer-review

• Is extending eligibility for adult social care better than investing more in existing users in England? A cross-sectional evidence for multiple financial years

  Longo, F., Claxton, K., Lomas, J. & Martin, S., 11 Sept 2023, In: BMJ Open. 13, 9, 10 p., e070833.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• More long-term care for better health care and vice versa: investigating the mortality effects of interactions between these public sectors

  Longo, F., Claxton, K. P., Martin, S. & Lomas, J., 20 Mar 2023, (E-pub ahead of print) In: Fiscal Studies. 28 p.

  Research output: Contribution to journal › Article › peer-review

• The impact of different types of NHS expenditure on health: Marginal cost per QALY estimates for England for 2016/17

  Martin, S., Claxton, K. P., Lomas, J. & Longo, F., 1 Jun 2023, In: Health Policy. 132, p. 104800 9 p., 104800.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2022

  Accounting for Country- and Time-Specific Values in the Economic Evaluation of Health-Related Projects Relevant to low- and Middle-Income Countries

  Lomas, J., Claxton, K. & Ochalek, J., Jan 2022, In: Health Policy and Planning. 37, 1, p. 45-54

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• How Responsive is Mortality to Locally Administered Healthcare Expenditure? Estimates for England for 2014/15

  Martin, S., Claxton, K., Lomas, J. & Longo, F., 1 Jul 2022, In: Applied Health Economics and Health Policy. 20, p. 557–572 16 p.

  Research output: Contribution to journal › Article › peer-review

• Reference Case Methods for Expert Elicitation in Health Care Decision Making

  Bojke, L., Soares, M. O., Claxton, K., Colson, A., Fox, A., Jackson, C., Jankovic, D., Morton, A., Sharples, L. D. & Taylor, A., 1 Feb 2022, In: Medical Decision Making. 42, 2, p. 182-193 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2021

  An Efficient Method for Computing Expected Value of Sample Information for Survival Data from an Ongoing Trial

  Vervaart, M., Strong, M., Claxton, K. P., Welton, N. J., Wisløff, T. & Aas, E., 30 Dec 2021, (E-pub ahead of print) In: Medical Decision Making. p. 272989X211068019

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Authors' Response to: "Health Opportunity Costs and Expert Elicitation: A Comment on Soares et al." by Sampson, Firth, and Towse

  Soares, M. O., Sculpher, M. J. & Claxton, K., 25 Feb 2021, (E-pub ahead of print) In: Medical Decision Making. 3 p., 272989X20987222.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Concomitant health benefits package design and research prioritisation: development of a new approach and an application to Malawi

  Schmitt, L., Ochalek, J., Claxton, K., Revill, P., Nkhoma, D. & Woods, B., 13 Dec 2021, In: BMJ Global health. 6, 12

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Developing a reference protocol for structured expert elicitation in health-care decision-making: a mixed-methods study

  Bojke, L., Soares, M., Claxton, K., Colson, A., Fox, A., Jackson, C., Jankovic, D., Morton, A., Sharples, L. & Taylor, A., 11 Jun 2021, In: Health technology assessment (Winchester, England). 25, 37, p. 1-124 124 p.

  Research output: Contribution to journal › Article › peer-review

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• Does public long-term care expenditure improve care-related quality of life of service users in England?

  Longo, F., Claxton, K., Lomas, J. & Martin, S., 8 Sept 2021, In: Health Economics. 30, 10, p. 2561-2581

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Estimating the shares of the value of branded pharmaceuticals accruing to manufacturers and to patients served by health systems

  Woods, B., Fox, A., Sculpher, M. & Claxton, K., 2 Aug 2021, (E-pub ahead of print) In: Health Economics. p. 1-18 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• How Effective is Marginal Healthcare Expenditure? New Evidence from England for 2003/04 to 2012/13

  Martin, S., Lomas, J., Claxton, K. & Longo, F., 1 Nov 2021, In: Applied Health Economics and Health Policy. 19, p. 885–903 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• The causal impact of social care, public health and healthcare expenditure on mortality in England: cross-sectional evidence for 2013/14

  Martin, S., Longo, F., Lomas, J. & Claxton, K., 15 Oct 2021, In: BMJ Open. 11, 10, e046417.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2020

  Assessing the value of human papillomavirus vaccination in Gavi-eligible low-income and middle-income countries

  Ochalek, J., Abbas, K., Claxton, K., Jit, M. & Lomas, J., 20 Oct 2020, In: BMJ Global health. 5, 10, 12 p., e003006.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Bayesian econometric modelling of observational data for cost-effectiveness analysis: establishing the value of Negative Pressure Wound Therapy in the healing of open surgical wounds

  Saramago Goncalves, P. R., Claxton, K. P., Welton, N. J. & Soares, M. O., 5 Oct 2020, In: Journal of the Royal Statistical Society: Series A (Statistics in Society). 183, 4, p. 1575-1593 19 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Estimating Social Variation in the Health Effects of Changes in Health Care Expenditure

  Love-Koh, J., Cookson, R., Claxton, K. & Griffin, S., Feb 2020, In: Medical Decision Making. 40, 2, p. 170-182 13 p., 272989X20904360.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Health Opportunity Costs: Assessing the Implications of Uncertainty Using Elicitation Methods with Experts

  Soares, M. O., Sculpher, M. J. & Claxton, K., 1 May 2020, In: Medical Decision Making. 40, 4, p. 448-459

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Is an ounce of prevention worth a pound of cure? A cross-sectional study of the impact of English public health grant on mortality and morbidity

  Martin, S., Lomas, J. & Claxton, K., 10 Oct 2020, In: BMJ Open. 10, 10, 12 p., e036411.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Practical metrics for establishing the health benefits of research to support research prioritisation

  Woods, B., Schmitt, L., Rothery, C., Phillips, A., Hallett, T. B., Revill, P. & Claxton, K., Aug 2020, In: BMJ Global health. 5, 8

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Surgical wounds healing by secondary intention: characterising and quantifying the problem, identifying effective treatments, and assessing the feasibility of conducting a randomised controlled trial of negative pressure wound therapy versus usual care

  Chetter, I., Arundel, C. E., Bell, K. J., Buckley, H., Claxton, K. P., Corbacho Martín, B., Cullum, N., Dumville, J., Fairhurst, C. M., Henderson, E., Lamb, K., Long, J., McCaughan, D. M., McGinnis, E., Oswald, A., Saramago Goncalves, P. R., Sheard, L., Soares, M. O., Stubbs, N., Torgerson, D. J., & 1 othersWelton, N., 21 Sept 2020, In: Programme Grants for Applied Research. 8, 7

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Value-based tiered pricing for universal health coverage: an idea worth revisiting

  Chalkidou, K., Claxton, K., Silverman, R. & Yadav, P., 21 Feb 2020, (Accepted/In press) In: Gates open research. 4, p. 16

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Valuing health outcomes: developing better defaults based on health opportunity costs

  Ochalek, J., Claxton, K., Lomas, J. & Thompson, K. M., 20 Sept 2020, (E-pub ahead of print) In: Expert Review of Pharmacoeconomics & Outcomes Research. p. 1-8 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• What next after GDP-based cost-effectiveness thresholds? [version 1; peer review: 2 approved]

  Chi, Y-L., Blecher, M., Chalkidou, K., Culyer, A., Claxton, K., Edoka, I., Glassman, A., Kreif, N., Jones, I., Mirelman, A. J., Nadjib, M., Morton, A., Norheim, O. F., Ochalek, J., Prinja, S., Ruiz, F., Teerawattananon, Y., Vassall, A. & Winch, A., 30 Nov 2020, In: Gates open research. 4, 12 p., 176.

  Research output: Contribution to journal › Article › peer-review

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• 2019

  Accounting for Timing when Assessing Health-Related Policies

  Claxton, K., Asaria, M., Chansa, C., Jamison, J., Lomas, J., Ochalek, J. & Paulden, M., 26 Jan 2019, In: Journal of Benefit-Cost Analysis. 10, Suppl 1, p. 73-105 34 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Estimating the marginal productivity of the English National Health Service from 2003 to 2012

  Lomas, J. R. S., Martin, S. & Claxton, K. P., Sept 2019, In: Value in Health. 22, 9, p. 995-1002 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• The Value of Further Research: The Added Value of Individual-Participant Level Data

  Saramago, P., Espinoza, M. A., Sutton, A. J., Manca, A. & Claxton, K., 23 Jan 2019, (E-pub ahead of print) In: Applied Health Economics and Health Policy.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2018

  Appraising the value of evidence generation activities: an HIV modelling study

  Woods, B., Rothery, C., Anderson, S-J., Eaton, J. W., Revill, P., Hallett, T. B. & Claxton, K., 7 Dec 2018, In: BMJ Global health. 3, 6, 21 p., e000488.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Estimating health opportunity costs in low-income and middle-income countries: a novel approach and evidence from cross-country data

  Ochalek, J., Lomas, J. & Claxton, K., 5 Nov 2018, In: BMJ Global health. 3, 6, p. 1-11 11 p., e000964.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Experiences of structured elicitation for model based cost-effectiveness analyses

  Soares, M. O., Sharples, L., Morton, A., Claxton, K. & Bojke, L., 15 Jun 2018, In: Value in Health. 21, 6, p. 715-723 9 p.

  Research output: Contribution to journal › Article › peer-review

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• Resolving the ‘cost-effective but unaffordable’ ‘paradox’: estimating the health opportunity costs of non-marginal budget impacts: Estimating the Health Opportunity Costs of Nonmarginal Budget Impacts

  Lomas, J., Claxton, K., Martin, S. & Soares, M., Mar 2018, In: Value in Health. 21, 3, p. 266-275 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Supporting the development of a health benefits package in Malawi

  Ochalek, J., Revill, P., Manthalu, G., McGuire, F., Nkhoma, D., Rollinger, A., Sculpher, M. & Claxton, K., 9 Apr 2018, In: BMJ Global health. 3, 2, 14 p., e000607.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• The impact of NHS expenditure on health outcomes in England: Alternative approaches to identification in all-cause and disease specific models of mortality

  Claxton, K., Lomas, J. & Martin, S., 2 Apr 2018, (E-pub ahead of print) In: Health Economics. 27, 6, p. 1017-1023 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2017

  A Cost-Effectiveness Analysis of Intradiscal Electrothermal Therapy (IDET) Compared with Circumferential Lumbar Fusion

  Stamuli, E., Kesornsak, W., Grevitt, M. P., Posnett, J. & Claxton, K., 12 Sept 2017, In: Pain practice : the official journal of World Institute of Pain.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Characterising uncertainty in the assessment of medical devices and determining future research needs

  Rothery, C., Claxton, K., Palmer, S., Epstein, D., Tarricone, R. & Sculpher, M., 31 Jan 2017, In: Health Economics. 26, (Suppl. 1), p. 109-123 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Developing a Value Framework: The Need to Reflect the Opportunity Costs of Funding Decisions

  Sculpher, M., Claxton, K. & Pearson, S. D., Feb 2017, In: Value in Health. 20, 2, p. 234-239 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• How to design the cost-effectiveness appraisal process of new healthcare technologies to maximise population health: A conceptual framework

  Johannesen, K. M., Claxton, K., Sculpher, M. J. & Wailoo, A. J., 22 Aug 2017, In: Health Economics. 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Social value and individual choice: The value of a choice-based decision-making process in a collectively funded health system

  Espinoza, M. A., Manca, A., Claxton, K. & Sculpher, M., 4 Oct 2017, (E-pub ahead of print) In: Health Economics. p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2016

  A Comprehensive Algorithm for Approval of Health Technologies With, Without, or Only in Research: The Key Principles for Informing Coverage Decisions

  Claxton, K., Palmer, S., Longworth, L., Bojke, L., Griffin, S., Soares, M., Spackman, E. & Rothery, C., 1 Sept 2016, In: Value in Health. 19, 6, p. 885-891 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Cancer Drugs Fund requires further reform: Reliance on “real world” observational data undermines evidence base for clinical practice

  Grieve, R., Abrams, K., Claxton, K. P., Goldacre, B., James, N., Nicholl, J., Parmar, M., Parker, C., Sekhon, J. S., Smeeth, L., Spiegelhalter, D. & Sculpher, M. J., 27 Sept 2016, In: British medical journal. 354, i5090.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Country-level cost-effectiveness thresholds: initial estimates and the need for further research

  Woods, B. S., Revill, P., Sculpher, M. J. & Claxton, K. P., Dec 2016, In: Value in Health. 19, 8, p. 929–935 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• Country-Level Cost-Effectiveness Thresholds: Initial Estimates and the Need for Further Research

  Woods, B., Revill, P., Sculpher, M. & Claxton, K., 14 Dec 2016, In: Value in Health. 19, 8, p. 929-935 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• International Society for Pharmacoeconomics and Outcomes Research Comments on the American Society of Clinical Oncology Value Framework

  Malone, D. C., Berg, N. S., Claxton, K., Garrison, L. P., IJzerman, M., Marsh, K., Neumann, P. J., Sculpher, M., Towse, A., Uyl-de Groot, C. & Weinstein, M. C., 13 Jun 2016, In: Journal of Clinical Oncology. 34, 24, p. 2936-2937 2 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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