Keith Sanderson Wilson

Search results

• 2024

  Catch-and-Release: The Assembly, Immobilisation and Recycling of Redox-reversible Artificial Metalloenzymes

  Miller, A. H., Blagova, E. V., Large, B., Booth, R. L., Wilson, K. S. & Duhme-Klair, A-K., 1 Mar 2024, In: ACS Catalysis. 14, 5, p. 3218-3227 10 p.

  Research output: Contribution to journal › Article › peer-review

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• Enhancement of growth media for extreme iron limitation in Escherichia coli

  Southwell, J. W., Wilson, K. S., Thomas, G. H. & Duhme-Klair, A-K., 3 Jun 2024, In: Access microbiology. 6, 6, 8 p., 000735.

  Research output: Contribution to journal › Article › peer-review

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• Kinetic and structural analysis of redox-reversible artificial imine reductases

  Miller, A. H., Martins, I. B. S., Blagova, E. V., Wilson, K. S. & Duhme-Klair, A-K., 6 Aug 2024, (E-pub ahead of print) In: JOURNAL OF INORGANIC BIOCHEMISTRY. 260, 7 p., 112691.

  Research output: Contribution to journal › Article › peer-review

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• Redox-reversible siderophore-based catalyst anchoring within cross-linked artificial metalloenzyme aggregates enables enantioselectivity switching

  Miller, A. H., Thompson, S., Blagova, L., Wilson, K. S., Grogan, G. J. & Duhme-Klair, A-K., 29 Apr 2024, (E-pub ahead of print) In: Chemical communications. 4 p.

  Research output: Contribution to journal › Article › peer-review

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• 2023

  Augmentation of growth media for extreme iron-limitation in Escherichia coli

  Southwell, J. W., Wilson, K. S., Thomas, G. H. & Duhme-Klair, A-K., 2023, In: Access Microbiology. p. 000735-v1

  Research output: Contribution to journal › Article › peer-review

• Module walking using an SH3-like cell-wall-binding domain leads to a new GH184 family of muramidases

  Moroz, O. V., Blagova, E., Lebedev, A. A., Skov, L. K., Pache, R. A., Schnorr, K. M., Kiemer, L., Friis, E. P., Nymand-Grarup, S., Ming, L., Ye, L., Klausen, M., Cohn, M. T., Schmidt, E. G. W., Davies, G. J. & Wilson, K. S., 1 Aug 2023, In: Acta crystallographica. Section D, Structural biology. 79, Pt 8, p. 706-720 15 p.

  Research output: Contribution to journal › Article › peer-review

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• Siderophore-linked Ruthenium Catalysts for Targeted Allyl Ester Prodrug Activation within Bacterial Cells

  Southwell, J., Herman, R., Raines, D., Clarke, J. E., Boeswald, I., Dreher, T., Gutenthaler, S., Schubert, N., Seefeldt, J., Metzler-Nolte, N., Thomas, G. H., Wilson, K. S. & Duhme-Klair, A-K., 8 Feb 2023, In: Chemistry : A European Journal. 29, 8, 10 p., e202202536.

  Research output: Contribution to journal › Article › peer-review

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• Structural and functional characterization of a multi-domain GH92 α-1,2-mannosidase from Neobacillus novalis

  Kołaczkowski, B. M., Moroz, O. V., Blagova, E., Davies, G. J., Møller, M. S., Meyer, A. S., Westh, P., Jensen, K., Wilson, K. S. & Krogh, K. B. R. M., 1 May 2023, In: Acta crystallographica. Section D, Structural biology. 79, p. 387-400 14 p.

  Research output: Contribution to journal › Article › peer-review

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• The CCP4 suite: integrative software for macromolecular crystallography

  Agirre, J., Atanasova, M., Bagdonas, H., Ballard, C. B., Baslé, A., Beilsten-Edmands, J., Borges, R. J., Brown, D. G., Burgos-Mármol, J. J., Berrisford, J. M., Bond, P. S., Caballero, I., Catapano, L., Chojnowski, G., Cook, A. G., Cowtan, K. D., Croll, T. I., Debreczeni, J. É., Devenish, N. E., Dodson, E. J., & 74 othersDrevon, T. R., Emsley, P., Evans, G., Evans, P. R., Fando, M., Foadi, J., Fuentes-Montero, L., Garman, E. F., Gerstel, M., Gildea, R. J., Hatti, K., Hekkelman, M. L., Heuser, P., Hoh, S. W., Hough, M. A., Jenkins, H. T., Jiménez, E., Joosten, R. P., Keegan, R. M., Keep, N., Krissinel, E. B., Kolenko, P., Kovalevskiy, O., Lamzin, V. S., Lawson, D. M., Lebedev, A. A., Leslie, A. G. W., Lohkamp, B., Long, F., Malý, M., McCoy, A. J., McNicholas, S. J., Medina, A., Millán, C., Murray, J. W., Murshudov, G. N., Nicholls, R. A., Noble, M. E. M., Oeffner, R., Pannu, N. S., Parkhurst, J. M., Pearce, N., Pereira, J., Perrakis, A., Powell, H. R., Read, R. J., Rigden, D. J., Rochira, W., Sammito, M., Sánchez Rodríguez, F., Sheldrick, G. M., Shelley, K. L., Simkovic, F., Simpkin, A. J., Skubak, P., Sobolev, E., Steiner, R. A., Stevenson, K., Tews, I., Thomas, J. M. H., Thorn, A., Valls, J. T., Uski, V., Usón, I., Vagin, A., Velankar, S., Vollmar, M., Walden, H., Waterman, D., Wilson, K. S., Winn, M. D., Winter, G., Wojdyr, M. & Yamashita, K., 1 Jun 2023, In: Acta crystallographica. Section D, Structural biology. 79, Pt 6, p. 449-461 13 p.

  Research output: Contribution to journal › Article › peer-review

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• Thermostable homologues of the periplasmic siderophore-binding protein CeuE from Geobacillus stearothermophilus and Parageobacillus thermoglucosidasius

  Blagova, L., Miller, A. H., Bennett, M., Booth, R., Dodson, E. J., Duhme-Klair, A-K. & Wilson, K. S., 28 Jul 2023, In: Acta Crystallographica Section D: Structural Biology. D79, p. 694-705 12 p.

  Research output: Contribution to journal › Article › peer-review

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• 2021

  Epitope Mapping of Exposed Tegument and Alimentary Tract Proteins Identifies Putative Antigenic Targets of the Attenuated Schistosome Vaccine

  Farias, L. P., Vance, G. M., Coulson, P. S., Vitoriano-Souza, J., Neto, A. P. D. S., Wangwiwatsin, A., Neves, L. X., Castro-Borges, W., McNicholas, S., Wilson, K. S., Leite, L. C. C. & Wilson, R. A., 3 Mar 2021, In: Frontiers in immunology. 11, p. 624613

  Research output: Contribution to journal › Article › peer-review

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• Fungal GH25 muramidases: New family members with applications in animal nutrition and a crystal structure at 0.78Å resolution

  Moroz, O. V., Blagova, E., Taylor, E., Turkenburg, J. P., Skov, L. K., Gippert, G. P., Schnorr, K. M., Ming, L., Ye, L., Klausen, M., Cohn, M. T., Schmidt, E. G. W., Nymand-Grarup, S., Davies, G. J. & Wilson, K. S., 12 Mar 2021, In: PLoS ONE. 16, e0248190.

  Research output: Contribution to journal › Article › peer-review

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• Multitasking in the gut: X-ray structure of a multidomain BbgIII from Bifidobacterium bifidum offers possible explanations for its alternative functions

  Moroz, O. V., Blagova, E., Lebedev, A. A., Rodríguez, F. S., Rigden, D. J., Tams, J. W., Wilting, R., Vester, J. K., Longhin, E., Hansen, G. H., Krogh, K. B. R. M., Pache, R. A., Davies, G. J. & Wilson, K. S., 18 Nov 2021, (E-pub ahead of print) In: Acta Crystallographica Section D: Structural Biology. 15 p., D77.

  Research output: Contribution to journal › Article › peer-review

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• 2020

  Artificial Imine Reductases: Developments and Future Directions

  Booth, R., Grogan, G. J., Wilson, K. S. & Duhme-Klair, A-K., 16 Oct 2020, In: RSC Chemical Biology. p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

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• Conformational heterogeneity of Savinase from NMR, HDX-MS and X-ray diffraction analysis

  Wu, S., Nguyen, T. T. T. N., Moroz, O. V., Turkenburg, J. P., Nielsen, J. E., Wilson, K. S., Rand, K. D. & Teilum, K., 26 Jun 2020, In: PeerJ. 8, 17 p., e9408.

  Research output: Contribution to journal › Article › peer-review

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• Predicting protein model correctness in Coot using machine learning

  Bond, P. S., Wilson, K. S. & Cowtan, K. D., 1 Aug 2020, In: Acta crystallographica. Section D, Structural biology. 76, Pt 8, p. 713-723 11 p.

  Research output: Contribution to journal › Article › peer-review

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• 2019

  Crystal structure and substrate interactions of an unusual fungal non-CBM carrying GH26 endo-β-mannanase from Yunnania penicillata

  Freiesleben, P. V., Moroz, O. V., Blagova, E., Wiemann, M., Spodsberg, N., Agger, J. W., Davies, G. J., Wilson, K. S., Stålbrand, H., Meyer, A. S. & Krogh, K. B. R. M., 1 Dec 2019, In: Scientific Reports. 9, 14 p., 2266.

  Research output: Contribution to journal › Article › peer-review

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• Dynamic and Functional Profiling of Xylan-Degrading Enzymes in Aspergillus Secretomes Using Activity-Based Probes

  Schröder, S. P., De Boer, C., McGregor, N. G. S., Rowland, R. J., Moroz, O., Blagova, E., Reijngoud, J., Arentshorst, M., Osborn, D., Morant, M. D., Abbate, E., Stringer, M. A., Krogh, K. B. R. M., Raich, L., Rovira, C., Berrin, J. G., Van Wezel, G. P., Ram, A. F. J., Florea, B. I., Van Der Marel, G. A., & 5 othersCodée, J. D. C., Wilson, K. S., Wu, L., Davies, G. J. & Overkleeft, H. S., 26 Jun 2019, In: ACS Central Science. 5, 6, p. 1067-1078 12 p.

  Research output: Contribution to journal › Article › peer-review

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• Mimicking salmochelin S1 and the interactions of its Fe(III) complex with periplasmic iron siderophore binding proteins CeuE and VctP

  Wilde, E. J., Blagova, E. V., Sanderson, T. J., Raines, D. J., Thomas, R. P., Routledge, A., Duhme-Klair, A-K. & Wilson, K. S., Jan 2019, In: JOURNAL OF INORGANIC BIOCHEMISTRY. 190, p. 75-84 10 p.

  Research output: Contribution to journal › Article › peer-review

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• Novel Inhibitory Function of the Rhizomucor miehei Lipase Propeptide and Three-Dimensional Structures of Its Complexes with the Enzyme

  Moroz, O. V., Blagova, E., Reiser, V., Saikia, R., Dalal, S., Jørgensen, C. I., Bhatia, V. K., Baunsgaard, L., Andersen, B., Svendsen, A. & Wilson, K. S., 7 Jun 2019, In: ACS Omega. 4, 6, p. 9964-9975 12 p.

  Research output: Contribution to journal › Article › peer-review

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• Structural and functional characterisation of three novel fungal amylases with enhanced stability and pH tolerance

  Roth, C., Moroz, O. V., Turkenburg, J. P., Blagova, E., Waterman, J., Ariza, A., Ming, L., Tianqi, S., Andersen, C., Davies, G. J. & Wilson, K. S., 3 Oct 2019, In: International Journal of Molecular Sciences. 20, 19, 15 p., 4902.

  Research output: Contribution to journal › Article › peer-review

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• The crystal structure of Rv2991 from Mycobacterium tuberculosis: An F ₄₂₀ binding protein with unknown function

  Benini, S., Haouz, A., Proux, F., Alzari, P. & Wilson, K., 1 May 2019, In: JOURNAL OF STRUCTURAL BIOLOGY. 206, 2, p. 216-224 9 p.

  Research output: Contribution to journal › Article › peer-review

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• The C-type lysozyme from the upper gastrointestinal tract of opisthocomus hoatzin, the stinkbird

  Taylor, E. J., Skjøt, M., Skov, L. K., Klausen, M., De Maria, L., Gippert, G. P., Turkenburg, J. P., Davies, G. J. & Wilson, K. S., 6 Nov 2019, In: International Journal of Molecular Sciences. 20, 22, 17 p., 5531.

  Research output: Contribution to journal › Article › peer-review

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• The structure of the AliC GH13 α-amylase from Alicyclobacillus sp. reveals the accommodation of starch branching points in the α-amylase family

  Agirre, J., Moroz, O., Meier, S., Brask, J., Munch, A., Hoff, T., Andersen, C., Wilson, K. S. & Davies, G. J., 1 Jan 2019, In: Acta crystallographica. Section D, Structural biology. 75, 1, p. 1-7 7 p.

  Research output: Contribution to journal › Article › peer-review

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• 2018

  CCP4i2: The new graphical user interface to the CCP4 program suite

  Potterton, L., Agirre, J., Ballard, C. C., Cowtan, K., Dodson, E., Evans, P. R., Jenkins, H. T., Keegan, R., Krissinel, E. B., Stevenson, K., Lebedev, A., Mcnicholas, S. J., Nicholls, R. A., Noble, M., Pannu, N. S., Roth, C., Sheldrick, G. M., Skubak, P., Turkenburg, J., Uski, V., & 5 othersvon Delft, F., Waterman, D. G., Wilson, K., Winn, M. & Wojdyr, M., 1 Feb 2018, In: Acta crystallographica. Section D, Structural biology. 74, 2, p. 68-84 17 p.

  Research output: Contribution to journal › Article › peer-review

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• Recent developments in MrBUMP: better search-model preparation, graphical interaction with search models, and solution improvement and assessment

  Keegan, R. M., McNicholas, S. J., Thomas, J. M. H., Simpkin, A. J., Simkovic, F., Uski, V., Ballard, C. C., Winn, M. D., Wilson, K. S. & Rigden, D. J., 1 Mar 2018, In: Acta crystallographica. Section D, Structural biology. 74, Pt 3, p. 167-182 16 p.

  Research output: Contribution to journal › Article › peer-review

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• Redox-switchable siderophore anchor enables reversible artificial metalloenzyme assembly

  Raines, D. J., Clarke, J. E., Blagova, E. V., Dodson, E. J., Wilson, K. S. & Duhme-Klair, A. K., 1 Sept 2018, In: Nature Catalysis. 1, 9, p. 680-688 9 p.

  Research output: Contribution to journal › Article › peer-review

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• Structural dynamics and catalytic properties of a multimodular xanthanase

  Moroz, O. V., Jensen, P. F., McDonald, S. P., McGregor, N., Blagova, E., Comamala, G., Segura, D. R., Anderson, L., Vasu, S. M., Rao, V. P., Giger, L., Sørensen, T. H., Monrad, R. N., Svendsen, A., Nielsen, J. E., Henrissat, B., Davies, G. J., Brumer, H., Rand, K. & Wilson, K. S., 6 Jul 2018, In: ACS Catalysis. 8, 7, p. 6021–6034 14 p.

  Research output: Contribution to journal › Article › peer-review

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• Structural insight into industrially relevant glucoamylases: flexible positions of starch-binding domains

  Roth, C., Moroz, O. V., Ariza, A., Skov, L. K., Ayabe, K., Davies, G. J. & Wilson, K. S., 1 May 2018, In: Acta crystallographica. Section D, Structural biology. 74, 5, p. 463-470 8 p.

  Research output: Contribution to journal › Article › peer-review

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• Structure of a Talaromyces pinophilus GH62 Arabinofuranosidase in complex with AraDNJ at 1.25 Å resolution

  Moroz, O. V., Sobala, L., Blagova, E., Coyle, T., Peng, W., Krogh, K. B. R. M., Stubbs, K. A., Wilson, K. S. & Davies, G. J., 1 Aug 2018, In: Acta Crystallographica Section F:Structural Biology Communications. F74, p. 490-495 6 p.

  Research output: Contribution to journal › Article › peer-review

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• 2017

  Carbohydrate structure: the rocky road to automation

  Agirre, J., Davies, G. J., Wilson, K. S. & Cowtan, K. D., 2017, In: CURRENT OPINION IN STRUCTURAL BIOLOGY. 44, p. 39-47 9 p.

  Research output: Contribution to journal › Article › peer-review

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• Interactions of the periplasmic binding protein CeuE with Fe(III) n-LICAM(4-) siderophore analogues of varied linker length

  Wilde, E. J., Hughes, A., Blagova, E. V., Moroz, O. V., Thomas, R. P., Turkenburg, J. P., Raines, D. J., Duhme-Klair, A-K. & Wilson, K. S., 6 Apr 2017, In: Scientific Reports. 7, p. 1-14 14 p., 45941.

  Research output: Contribution to journal › Article › peer-review

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• Structural Characterization of Acidic M17 Leucine Aminopeptidases from the TriTryps and Evaluation of Their Role in Nutrient Starvation in Trypanosoma brucei

  Timm, J., Valente, M., García-Caballero, D., Wilson, K. S. & González-Pacanowska, D., 18 Aug 2017, In: mSphere. 2, 4, 17 p.

  Research output: Contribution to journal › Article › peer-review

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• The structure of a calcium-dependent phosphoinositide-specific phospholipase C from Pseudomonas sp. 62186, the first from a Gram-negative bacterium

  Moroz, O. V., Blagova, E., Lebedev, A. A., Nørgaard, A., Segura, D. R., Blicher, T. H., Brask, J. & Wilson, K. S., 1 Jan 2017, In: Acta crystallographica. Section D, Structural biology. 73, 1, p. 32-44 13 p.

  Research output: Contribution to journal › Article › peer-review

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• 2016

  Bacteria in an intense competition for iron: Key component of the Campylobacter jejuni iron uptake system scavenges enterobactin hydrolysis product

  Raines, D. J., Moroz, O. V., Blagova, E. V., Turkenburg, J. P., Wilson, K. S. & Duhme-Klair, A-K., 24 May 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 21, p. 5850-5855 6 p.

  Research output: Contribution to journal › Article › peer-review

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• Cell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma brucei

  Valente, M., Timm, J., Castillo-Acosta, V. M., Ruiz-Pérez, L. M., Balzarini, T., Nettleship, J. E., Bird, L. E., Rada, H., Wilson, K. S. & González-Pacanowska, D., 1 Nov 2016, In: Molecular Microbiology. 102, 3, p. 365-385 21 p.

  Research output: Contribution to journal › Article › peer-review

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• Three-dimensional structures of two heavily N-glycosylated Aspergillus sp. family GH3 β-D-glucosidases

  Agirre, J., Ariza, A., Offen, W. A., Turkenburg, J. P., Roberts, S. M., McNicholas, S., Harris, P. V., McBrayer, B., Dohnalek, J., Cowtan, K. D., Davies, G. J. & Wilson, K. S., 1 Feb 2016, In: Acta crystallographica. Section D, Structural biology. 72, 2, p. 254-265 12 p.

  Research output: Contribution to journal › Article › peer-review

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• 2015

  Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major

  Timm, J., Bosch-Navarrete, C., Recio, E., Nettleship, J. E., Rada, H., González-Pacanowska, D. & Wilson, K. S., 15 May 2015, In: PLOS NEGLECTED TROPICAL DISEASES. 9, 5, e0003781.

  Research output: Contribution to journal › Article › peer-review

• The substrate-binding protein in bacterial ABC transporters: Dissecting roles in the evolution of substrate specificity

  Maqbool, A., Horler, R. S. P., Muller, A., Wilkinson, A. J., Wilson, K. S. & Thomas, G. H., 9 Oct 2015, In: Biochemical Society transactions. 43, 5, p. 1011-1017 7 p.

  Research output: Contribution to journal › Article › peer-review

• The three-dimensional structure of the cellobiohydrolase Cel7A from Aspergillus fumigatus at 1.5Å resolution

  Moroz, O. V., Maranta, M., Shaghasi, T., Harris, P. V., Wilson, K. S. & Davies, G. J., 1 Jan 2015, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 71, p. 114-120 7 p.

  Research output: Contribution to journal › Article › peer-review

• Three-dimensional structure of a variant 'Termamyl-like' Geobacillus stearothermophilus α-amylase at 1.9Å resolution

  Offen, W. A., Viksoe-Nielsen, A., Borchert, T. V., Wilson, K. S. & Davies, G. J., Jan 2015, In: Acta Crystallographica Section F:Structural Biology Communications. 71, 1, p. 66-70 5 p.

  Research output: Contribution to journal › Article › peer-review
• 2014

  Analysis of an industrial production suspension of Bacillus lentus subtilisin crystals by powder diffraction: A powerful quality-control tool

  Frankaer, C. G., Moroz, O. V., Turkenburg, J. P., Aspmo, S. I., Thymark, M., Friis, E. P., Stahl, K., Nielsen, J. E., Wilson, K. S. & Harris, P., Apr 2014, In: Acta Crystallographica. Section D, Biological Crystallography. 70, 4, p. 1115-1123 9 p.

  Research output: Contribution to journal › Article › peer-review

• Structures of adenosine kinase from Trypanosoma brucei brucei

  Timm, J., González-Pacanowska, D. & Wilson, K. S., Jan 2014, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 70, 1, p. 34-39 6 p.

  Research output: Contribution to journal › Article › peer-review

• Thermodynamic and structural investigation of the specific SDS binding of humicola insolens cutinase

  Kold, D., Dauter, Z., Laustsen, A. K., Brzozowski, A. M., Turkenburg, J. P., Nielsen, A. D., Koldsø, H., Petersen, E., Schiøtt, B., De Maria, L., Wilson, K. S., Svendsen, A. & Wimmer, R., Aug 2014, In: Protein science. 23, 8, p. 1023-1035 13 p.

  Research output: Contribution to journal › Article › peer-review
• 2013

  Crystal and solution studies reveal that the transcriptional regulator AcnR of Corynebacterium glutamicum is regulated by citrate-Mg binding to a non-canonical pocket

  García-Nafría, J., Turkenburg, J. P., Wilkinson, A. J., Wilson, K. S., Baumgart, M. & Bott, M., 31 May 2013, In: The Journal of biological chemistry. 288, 22, p. 15800-15812 13 p.

  Research output: Contribution to journal › Article › peer-review

• Crystal structure of the small GTPase Arl6/BBS3 from Trypanosoma brucei

  Hemsworth, G. R., Price, H. P., Smith, D. F. & Wilson, K. S., Feb 2013, In: Protein Science. 22, 2, p. 196-203 8 p.

  Research output: Contribution to journal › Article › peer-review

• Degradation of phytate by the 6-phytase from hafnia alvei: A combined structural and solution study

  Ariza, A., Moroz, O. V., Blagova, E. V., Turkenburg, J. P., Waterman, J., Roberts, S. M., Wilson, K. S., Vind, J., Sjøholm, C., Lassen, S. F., de Maria, L., Glitsoe, V. & Skov, L. K., 31 May 2013, In: PLoS ONE. 8, 5, e65062.

  Research output: Contribution to journal › Article › peer-review

• Interactions of a periplasmic binding protein with a tetradentate siderophore mimic

  Duhme-Klair, A-K., Wilson, K. S., Moroz, O. & Raines, D. J., 22 Apr 2013, In: Angewandte Chemie International Edition. 52, 17, p. 4595-4598 4 p.

  Research output: Contribution to journal › Article › peer-review

• Mechanism of Protein Kinetic Stabilization by Engineered Disulfide Crosslinks

  Sanchez-Romero, I., Ariza, A., Wilson, K. S., Skjøt, M., Vind, J., de Maria, L., Skov, L. K. & Sanchez-Ruiz, J. M., 30 Jul 2013, In: PLoS ONE. 8, 7, e70013.

  Research output: Contribution to journal › Article › peer-review

• On the catalytic mechanism of dimeric dUTPases

  Hemsworth, G. R., González-Pacanowska, D. & Wilson, K. S., 15 Nov 2013, In: Biochemical journal. 456, 1, p. 81-8 8 p.

  Research output: Contribution to journal › Article › peer-review