Lukasz Sobala

10 Article

An epoxide intermediate in glycosidase catalysis
Sobala, L. F., Speciale, G., Zhu, S., Raich, L., Sannikova, N., Thompson, A. J., Hakki, Z., Lu, D., Abadi, S. S. K., Lewis, A. R., Rojas-Cervellera, V., Bernardo-Seisdedos, G., Zhang, Y., Millet, O., Jiménez-Barbero, J., Bennet, A. J., Sollogoub, M., Rovira, C., Davies, G. J. & Williams, S. J., 27 May 2020, In: ACS Central Science. 6, 5, p. 760-770
Research output: Contribution to journal › Article › peer-review

Open Access
File
Structure of human endo-a-1,2-mannosidase (MANEA), an antiviral host-glycosylation target
Sobala, L. F., Fernandes, P. Z., Hakki, Z., Thompson, A. J., Howe, J. D., Hill, M., Zitzmann, N., Davies, S., Stamataki, Z., Butters, T. D., Alonzi, D. S., Williams, S. J. & Davies, G. J., 24 Nov 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 47, p. 29595-29601 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
A family of dual-activity glycosyltransferasesphosphorylases mediates mannogen turnover and virulence in Leishmania parasites
Sernee, M. F., Ralton, J. E., Nero, T. L., Sobala, L. F., Kloehn, J., Viera-Lara, M., Cobbold, S. A., Stanton, L., Pires, D. E. V., Hanssen, E., Males, A., Ward, T., Bastidas, L. M., Peet, P. L. V. D., Parker, M. W., Ascher, D. B., Williams, S. J., Davies, G. J. & McConville, M. J., 11 Sept 2019, In: Cell Host & Microbe. 26, 3, p. 385-399 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

Diffraction images used to solve the structures published in the article "From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase"
Sobala, Ł. F. (Creator), Davies, G. J. (Creator), Lu, D. (Contributor), Zhu, S. (Contributor), Bernardo-Seisdedos, G. (Contributor), Millet, O. (Contributor), Zhang, Y. (Contributor), Jiménez-Barbero, J. (Contributor) & Sollogoub, M. (Contributor), Zenodo, 2 Feb 2021
DOI: 10.5281/zenodo.4431702
Dataset
Diffraction images used to solve the structures published in the article "Exploration of Strategies for Mechanism-Based Inhibitor Design for Family GH99 endo-alpha-1,2-Mannanases."
Sobala, Ł. F. (Creator), Davies, G. J. (Creator), Fernandes, P. Z. (Contributor), Petricevic, M. (Contributor) & Williams, S. J. (Contributor), Zenodo, 20 Jan 2021
DOI: 10.5281/zenodo.4446245
Dataset
Diffraction images used to solve the structures published in the article "Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase"
Sobala, Ł. F. (Creator), Thompson, A. J. (Creator), Davies, G. J. (Creator), Petricevic, M. (Contributor), Fernandes, P. Z. (Contributor), Raich, L. (Contributor), Bernardo-Seisdedos, G. (Contributor), Millet, O. (Contributor), Sollogoub, M. (Contributor), Jiménez-Barbero, J. (Contributor), Rovira, C. (Contributor) & Williams, S. J. (Contributor), Zenodo, 1 Feb 2021
DOI: 10.5281/zenodo.4300323
Dataset

Lukasz Sobala

Collaborations and top research areas from the last five years

Dive into details

An epoxide intermediate in glycosidase catalysis

Structure of human endo-a-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

A family of dual-activity glycosyltransferasesphosphorylases mediates mannogen turnover and virulence in Leishmania parasites

Diffraction images used to solve the structures published in the article "From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase"

Diffraction images used to solve the structures published in the article "Exploration of Strategies for Mechanism-Based Inhibitor Design for Family GH99 endo-alpha-1,2-Mannanases."

Diffraction images used to solve the structures published in the article "Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase"

Lukasz Sobala

Collaborations and top research areas from the last five years

Research output

An epoxide intermediate in glycosidase catalysis

Structure of human endo-a-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

A family of dual-activity glycosyltransferasesphosphorylases mediates mannogen turnover and virulence in Leishmania parasites

Datasets

Diffraction images used to solve the structures published in the article "From 1,4-Disaccharide to 1,3-Glycosyl Carbasugar: Synthesis of a Bespoke Inhibitor of Family GH99 Endo-α-mannosidase"

Diffraction images used to solve the structures published in the article "Exploration of Strategies for Mechanism-Based Inhibitor Design for Family GH99 endo-alpha-1,2-Mannanases."

Diffraction images used to solve the structures published in the article "Contribution of Shape and Charge to the Inhibition of a Family GH99 endo-α-1,2-Mannanase"