Lynette Beattie

Search results

• 2018

  Macrophage transactivation for chemokine production identified as a negative regulator of granulomatous inflammation using agent-based modeling

  Moyo, D., Beattie, L., Andrews, P. S., Moore, J. W. J., Timmis, J. I., Sawtell, A. K., Hoehme, S., Sampson, A. T. & Kaye, P., 27 Mar 2018, In: Frontiers in immunology. 9, 637, 10 p., 637.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2017

  In vivo imaging of systemic transport and elimination of xenobiotics and endogenous molecules in mice

  Reif, R., Ghallab, A., Beattie, L., Günther, G., Kuepfer, L., Kaye, P. M. & Hengstler, J. G., Mar 2017, In: Archives of toxicology. 91, 3, p. 1335-1352 18 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2016

  Bone marrow-derived and resident liver macrophages display unique transcriptomic signatures but similar biological functions

  Beattie, L., Sawtell, A. K., Mann, J., Frame, T. C. M., Teal, B., de Labastida Rivera, F., Brown, N., Walwyn-Brown, K., Moore, J. W. J., MacDonald, A. J., Lim, E.-K., Dalton, J. E., Engwerda, C. R., MacDonald, K. P. & Kaye, P., 1 Oct 2016, In: Journal of Hepatology. 65, 4, p. 758-768 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2015

  Bile canalicular dynamics in hepatocyte sandwich cultures

  Reif, R., Karlsson, J., Günther, G., Beattie, L., Wrangborg, D., Hammad, S., Begher-Tibbe, B., Vartak, A., Melega, S., Kaye, P. M., Hengstler, J. G. & Jirstrand, M., 18 Aug 2015, In: Archives of toxicology. 89, 10, p. 1861-70 10 p.

  Research output: Contribution to journal › Article › peer-review

• Lessons from other diseases: granulomatous inflammation in leishmaniasis

  Kaye, P. M. & Beattie, L., 17 Dec 2015, In: Seminars in immunopathology. p. 1-12 12 p.

  Research output: Contribution to journal › Article › peer-review

• The Neurotrophic Receptor Ntrk2 Directs Lymphoid Tissue Neovascularization during Leishmania donovani Infection

  Dalton, J. E., Glover, A. C., Hoodless, L., Lim, E. K., Beattie, L., Kirby, A. & Kaye, P. M., 24 Feb 2015, In: PLOS PATHOGENS. 11, 2, e1004681.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2013

  A petri net model of granulomatous inflammation: implications for IL-10 mediated control of leishmania donovani Infection

  Albergante, L., Timmis, J., Beattie, L. & Kaye, P., 21 Nov 2013, In: PLoS Computational Biology. 9, 11, 1003334.

  Research output: Contribution to journal › Article › peer-review

• A transcriptomic network identified in uninfected macrophages responding to inflammation controls intracellular pathogen survival

  Beattie, L., d'El-Rei Hermida, M., Moore, J. W. J., Maroof, A., Brown, N., Lagos, D. & Kaye, P. M., 11 Sept 2013, In: Cell Host & Microbe. 14, 3, p. 357-68 12 p.

  Research output: Contribution to journal › Article › peer-review

• Functional complexity of the Leishmania granuloma and the potential of in silico modelling

  Moore, J. W. J., Moyo, D., Beattie, L., Andrews, P. S., Timmis, J. & Kaye, P., 15 Feb 2013, In: Frontiers in immunology. 4, FRB, 35.

  Research output: Contribution to journal › Article › peer-review
• 2012

  B Cell: T Cell Interactions Occur within Hepatic Granulomas during Experimental Visceral Leishmaniasis

  Moore, J. W. J., Beattie, L., Dalton, J. E., Owens, B. M. J., Maroof, A., Coles, M. C. & Kaye, P. M., 30 Mar 2012, In: PLoS ONE. 7, 3, p. - 14 p., e34143.

  Research output: Contribution to journal › Article › peer-review

• IL-10-producing Th1 cells and disease progression are regulated by distinct CD11c⁺ cell populations during visceral leishmaniasis

  Owens, B. M. J., Beattie, L., Moore, J. W. J., Brown, N., Mann, J. L., Dalton, J. E., Maroof, A. & Kaye, P. M., Jul 2012, In: PLOS PATHOGENS. 8, 7, p. 1-13 13 p., e1002827.

  Research output: Contribution to journal › Article › peer-review
• 2011

  Compartment-Specific Remodeling of Splenic Micro-Architecture during Experimental Visceral Leishmaniasis

  Yurdakul, P., Dalton, J. E., Beattie, L., Brown, N., Erguven, S., Maroof, A. & Kaye, P. M., Jul 2011, In: American Journal of Pathology. 179, 1, p. 23-29 7 p.

  Research output: Contribution to journal › Article › peer-review

• Interferon Regulatory Factor 7 Contributes to the Control of Leishmania donovani in the Mouse Liver

  Beattie, L., Phillips, R., Brown, N., Owens, B. M. J., Chauhan, N., Dalton, J. E. & Kaye, P. M., Mar 2011, In: Infection and Immunity. 79, 3, p. 1057-1066 10 p.

  Research output: Contribution to journal › Article › peer-review

• Leishmania-host interactions: what has imaging taught us?

  Beattie, L. & Kaye, P. M., Nov 2011, In: Cellular Microbiology. 13, 11, p. 1659-67 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2010

  Dynamic Imaging of Experimental Leishmania donovani-Induced Hepatic Granulomas Detects Kupffer Cell-Restricted Antigen Presentation to Antigen-Specific CD8+ T Cells

  Beattie, L., Peltan, A., Maroof, A., Kirby, A., Brown, N., Coles, M., Smith, D. F. & Kaye, P. M., 12 Mar 2010, In: PLOS PATHOGENS. 6, 3, 17 p., e1000805.

  Research output: Contribution to journal › Article › peer-review

• Inhibition of receptor tyrosine kinases restores immunocompetence and improves immune-dependent chemotherapy against experimental leishmaniasis in mice

  Dalton, J. E., Maroof, A., Owens, B. M. J., Narang, P., Johnson, K., Brown, N., Rosenquist, L., Beattie, L., Coles, M. & Kaye, P. M., 1 Apr 2010, In: Journal of Clinical Investigation. 120, 4, p. 1204-1216 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7

  Phillips, R., Svensson, M., Aziz, N., Maroof, A., Brown, N., Beattie, L., Signoret, N. & Kaye, P. M., Mar 2010, In: PLOS PATHOGENS. 6, 3, e1000813.

  Research output: Contribution to journal › Article › peer-review

• Leishmania donovani-induced expression of signal regulatory protein alpha on Kupffer cells enhances hepatic invariant NKT-cell activation

  Beattie, L., Svensson, M., Bune, A., Brown, N., Maroof, A., Zubairi, S., Smith, K. R. & Kaye, P. M., Jan 2010, In: European Journal of Immunology. 40, 1, p. 117-123 7 p.

  Research output: Contribution to journal › Article › peer-review
• 2009

  Dendritic Cells Matured by Inflammation Induce CD86-Dependent Priming of Naive CD8(+) T Cells in the Absence of Their Cognate Peptide Antigen

  Maroof, A., Beattie, L., Kirby, A., Coles, M. & Kaye, P. M., 1 Dec 2009, In: Journal of Immunology. 183, 11, p. 7095-7103 9 p.

  Research output: Contribution to journal › Article › peer-review

• SIGNR1-Negative Red Pulp Macrophages Protect against Acute Streptococcal Sepsis after Leishmania donovani-Induced Loss of Marginal Zone Macrophages

  Kirby, A. C., Beattie, L., Maroof, A., van Rooijen, N. & Kaye, P. M., Sept 2009, In: American Journal of Pathology. 175, 3, p. 1107-1115 9 p.

  Research output: Contribution to journal › Article › peer-review
• 2008

  Posttranscriptional regulation of Il10 gene expression allows natural killer cells to express immunoregulatory function

  Maroof, A., Beattie, L., Zubairi, S., Svensson, M., Stager, S. & Kaye, P. M., 15 Aug 2008, In: Immunity. 29, 2, p. 295-305 11 p.

  Research output: Contribution to journal › Article › peer-review

• Transgenic Leishmania and the immune response to infection

  Beattie, L., Evans, K. J., Kaye, P. M. & Smith, D. F., Apr 2008, In: Parasite immunology. 30, 4, p. 255-266 12 p.

  Research output: Contribution to journal › Article › peer-review
• 2007

  Matrix metalloproteinase-9 expression in spleen during L-donovani infection

  Yurdakul, P., Beattie, L., Maroof, A. & Kaye, P., Mar 2007, In: Immunology. 120, p. 62-62 1 p.

  Research output: Contribution to journal › Article › peer-review