Research output per year
Research output per year
- 16 results
Search results
-
2024
A multiplexed, confinable CRISPR/Cas9 gene drive propagates in caged Aedes aegypti populations
Anderson, M., Gonzalez Fernandez, E., Edgington, M. P., Ang Xin De, J., Purusothaman, D.-K., Shackleford, L., Nevard, K., Verkuijl, S., Harvey-Samuel, T., Leftwich, P., Esvelt, K. & Alphey, L. S., 25 Jan 2024, In: Nature Communications. 15, 13 p., 729.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2023
Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements
Anderson, M., Gonzalez Fernandez, E., Ang Xin De, J., Shackleford, L., Nevard, K., Verkuijl, S., Edgington, M. P., Harvey-Samuel, T. & Alphey, L. S., 20 Jan 2023, In: Nature Communications. 14, p. 1-9 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2022
Chapter 12 Modelling Threshold-Dependent Gene Drives: a Case Study Using Engineered Underdominance
Edgington, M. P. & Alphey, L. S., Nov 2022, Transgenic Insects: Techniques and Applications. 2 ed. CABI International, p. 259-278Research output: Chapter in Book/Report/Conference proceeding › Chapter
Open Access -
2021
Genetic pest management and the background genetics of release strains: GPM & background genetics
Leftwich, P. T., Spurgin, L. G., Harvey-Samuel, T., Thomas, C. J. E., Paladino, L. C., Edgington, M. P. & Alphey, L., 15 Feb 2021, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 376, 1818, 20190804.Research output: Contribution to journal › Review article › peer-review
Open Access -
2020
Genetic Biocontrol for Invasive Species
Teem, J. L., Alphey, L., Descamps, S., Edgington, M. P., Edwards, O., Gemmell, N., Harvey-Samuel, T., Melnick, R. L., Oh, K. P., Piaggio, A. J., Saah, J. R., Schill, D., Thomas, P., Smith, T. & Roberts, A., 25 May 2020, In: Frontiers in Bioengineering and Biotechnology. 8, 452.Research output: Contribution to journal › Review article › peer-review
Open Access -
Population-level multiplexing: A promising strategy to manage the evolution of resistance against gene drives targeting a neutral locus
Edgington, M. P., Harvey-Samuel, T. & Alphey, L., 2 Sept 2020, In: Evolutionary applications. 13, 8, p. 1939-1948 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Split drive killer-rescue provides a novel threshold-dependent gene drive
Edgington, M. P., Harvey-Samuel, T. & Alphey, L., 25 Nov 2020, In: Scientific reports. 10, 1, 20520.Research output: Contribution to journal › Article › peer-review
Open Access -
Transmission efficiency drives host-microbe associations
Leftwich, P. T., Edgington, M. P. & Chapman, T., 9 Sept 2020, In: Proceedings of the Royal Society B: Biological Sciences. 287, 1934, 20200820.Research output: Contribution to journal › Article › peer-review
Open Access -
2019
Modeling the mutation and reversal of engineered underdominance gene drives
Edgington, M. P. & Alphey, L. S., 21 Oct 2019, In: JOURNAL OF THEORETICAL BIOLOGY. 479, p. 14-21 8 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Trialling gene drives to control invasive species: what, where and how?
Edgington, M. P., Alphey, L. S., Harvey-Samuel, T. & Campbell, K. J., 2019, Island Invasives: Scaling up to meet the challenge. Proceedings of the international conference on island invasives 2017. IUCN, National Committee United Kingdom, Vol. 62. p. 618-627 (Occasional Paper of the IUCN Species Survival Commission; vol. 62).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
-
2018
Mathematical Analysis of the Escherichia coli Chemotaxis Signalling Pathway
Edgington, M. P. & Tindall, M. J., 5 Feb 2018, (E-pub ahead of print) In: Bulletin of Mathematical Biology. 80, 4, p. 758-787 30 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Population dynamics of engineered underdominance and killer-rescue gene drives in the control of disease vectors
Edgington, M. P. & Alphey, L. S., Mar 2018, In: PLoS Computational Biology. 14, 3, e1006059.Research output: Contribution to journal › Article › peer-review
Open Access -
Recent advances in threshold-dependent gene drives for mosquitoes
Leftwich, P. T., Edgington, M. P., Harvey-Samuel, T., Carabajal Paladino, L. Z., Norman, V. C. & Alphey, L., 6 Sept 2018, In: Biochemical Society transactions. 46, 5, p. 1203-1212 10 p.Research output: Contribution to journal › Review article › peer-review
Open Access -
2017
Conditions for success of engineered underdominance gene drive systems
Edgington, M. P. & Alphey, L. S., 7 Oct 2017, In: JOURNAL OF THEORETICAL BIOLOGY. 430, p. 128-140 13 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2015
Understanding the link between single cell and population scale responses of Escherichia coli in differing ligand gradients
Edgington, M. P. & Tindall, M. J., 2015, In: Computational and Structural Biotechnology Journal. 13, p. 528-38 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
2014
Fold-change detection in a whole-pathway model of Escherichia coli chemotaxis
Edgington, M. P. & Tindall, M. J., Jun 2014, In: Bulletin of Mathematical Biology. 76, 6, p. 1376-95 20 p.Research output: Contribution to journal › Article › peer-review