Nathaniel Jones

Search results

• 2023

  Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery

  Russell, C., Carter, J., Borgia, J. M., Bush, J., Calderón, F., Gabarró, R., Conway, S., Mottram, J. C., Wilkinson, A. J. & Jones, N., 31 Oct 2023, (E-pub ahead of print) In: ACS Infectious Diseases. 18 p.

  Research output: Contribution to journal › Article › peer-review

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• 2022

  Bromodomain factor 5 is an essential regulator of transcription in Leishmania

  Jones, N. G., Geoghegan, V., Moore, G., Carnielli, J. B. T., Newling, K., Calderón, F., Gabarró, R., Martín, J., Prinjha, R. K., Rioja, I., Wilkinson, A. J. & Mottram, J. C., 13 Jul 2022, In: Nature Communications. 13, 1, 18 p., 4071.

  Research output: Contribution to journal › Article › peer-review

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• CLK1/CLK2 driven signalling at the Leishmania kinetochore is captured by spatially referenced proximity phosphoproteomics

  Geoghegan, V., Carnielli, J. B. T., Jones, N., Saldivia, M., Antoniou, S., Hughes, C., Neish, R., Dowle, A. & Mottram, J. C., 28 Nov 2022, In: Communications Biology.

  Research output: Contribution to journal › Article › peer-review

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• Tag thy neighbour: nanometre-scale insights into kinetoplastid parasites with proximity dependent biotinylation

  Geoghegan, V., Mottram, J. C. & Jones, N., 6 May 2022, In: Frontiers in cellular and infection microbiology.

  Research output: Contribution to journal › Article › peer-review

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• 2019

  The secreted kinase ROP17 promotes Toxoplasma gondii dissemination by hijacking monocyte tissue migration

  Drewry, L. L., Jones, N. G., Wang, Q., Onken, M. D., Miller, M. J. & Sibley, L. D., 22 Jul 2019, In: Nature Microbiology. 4, 11, p. 1951-1963 13 p.

  Research output: Contribution to journal › Article › peer-review
• 2018

  Genetically Validated Drug Targets in Leishmania: Current Knowledge and Future Prospects

  Jones, N., Catta Preta, C., Lima, A. P. C. A. & Mottram, J. C., 13 Apr 2018, In: ACS Infectious Diseases. 4, 4, p. 467-477 11 p.

  Research output: Contribution to journal › Article › peer-review

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• 2017

  Inhibition of Calcium Dependent Protein Kinase 1 (CDPK1) by Pyrazolopyrimidine Analogs Decreases Establishment and Reoccurrence of Central Nervous System Disease by Toxoplasma gondii.

  Rutaganira, F. U., Barks, J., Dhason, M. S., Wang, Q., Lopez, M. S., Long, S., Radke, J. B., Jones, N. G., Maddirala, A. R., Janetka, J. W., El Bakkouri, M., Hui, R., Shokat, K. M. & Sibley, L. D., 28 Dec 2017, In: JOURNAL OF MEDICINAL CHEMISTRY. 60, 24, 14 p., 9976–9989.

  Research output: Contribution to journal › Article › peer-review

• Recent advances in Leishmania reverse genetics: Manipulating a manipulative parasite

  Duncan, S. M., Jones, N. G. & Mottram, J. C., Sept 2017, In: MOLECULAR AND BIOCHEMICAL PARASITOLOGY. 216, p. 30-38 9 p.

  Research output: Contribution to journal › Article › peer-review

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• RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse

  Fernandez-Cortes, F., Serafim, T. D., Wilkes, J. M., Jones, N. G., Ritchie, R., McCulloch, R. & Mottram, J. C., 21 Jul 2017, In: Scientific Reports. 7, 1, 10 p., 6156.

  Research output: Contribution to journal › Article › peer-review

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• Secreted protein kinases regulate cyst burden during chronic toxoplasmosis

  Jones, N. G., Wang, Q. & Sibley, L. D., 17 Jan 2017, In: Cellular Microbiology. 19, 2, 13 p., e12651.

  Research output: Contribution to journal › Article › peer-review

• 2016

  Identification of Small Molecule Inhibitors That Block the Toxoplasma gondii Rhoptry Kinase ROP18

  Simpson, C., Jones, N. G., Hull-Ryde, E. A., Kireev, D., Stashko, M., Tang, K., Janetka, J. W., Wildman, S. A., Zuercher, W. J., Schapira, M., Hui, R., Janzen, W. & Sibley, L. D., 2016, In: ACS Infectious Diseases. p. acsinfecdis.5b00102

  Research output: Contribution to journal › Article › peer-review

• Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore- dependent disruption

  Jimah, J. R., Salinas, N. D., Sala-rabanal, M., Jones, N. G., Sibley, L. D., Nichols, C. G., Schlesinger, P. H. & Tolia, N. H., 1 Dec 2016, In: eLife. 5, p. 1-17 17 p., e20621.

  Research output: Contribution to journal › Article › peer-review

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• 2014

  Regulators of Trypanosoma brucei Cell Cycle Progression and Differentiation Identified Using a Kinome-Wide RNAi Screen

  Jones, N. G., Thomas, E. B., Brown, E., Dickens, N. J., Hammarton, T. C. & Mottram, J. C., 16 Jan 2014, In: PLOS PATHOGENS. 10, 1, 16 p., e1003886.

  Research output: Contribution to journal › Article › peer-review

  Open Access

• Tracking autophagy during proliferation and differentiation of Trypanosoma brucei.

  Proto, W. R., Jones, N. G., Coombs, G. H. & Mottram, J. C., 1 Jan 2014, In: Microbial cell (Graz, Austria). 1, 1, p. 9-20 12 p.

  Research output: Contribution to journal › Article › peer-review

• 2013

  Trypanosoma brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes

  Elliott, E. B., McCarroll, D., Hasumi, H., Welsh, C. E., Panissidi, A. A., Jones, N. G., Rossor, C. L., Tait, A., Smith, G. L., Mottram, J. C., Morrison, L. J. & Loughrey, C. M., 1 Nov 2013, In: Cardiovascular research. 100, 2, p. 325-35 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2008

  Blood meal identification and parasite detection in laboratory-fed and field-captured Lutzomyia longipalpis by PCR using FTA databasing paper.

  Sant'Anna, M. R. V., Jones, N. G., Hindley, J. A., Mendes-Sousa, A. F., Dillon, R. J., Cavalcante, R. R., Alexander, B. & Bates, P. A., 1 Sept 2008, In: Acta tropica. 107, 3, p. 230-237 8 p.

  Research output: Contribution to journal › Article › peer-review