Pat Coulson

Search results

• 2021

  Epitope Mapping of Exposed Tegument and Alimentary Tract Proteins Identifies Putative Antigenic Targets of the Attenuated Schistosome Vaccine

  Farias, L. P., Vance, G. M., Coulson, P. S., Vitoriano-Souza, J., Neto, A. P. D. S., Wangwiwatsin, A., Neves, L. X., Castro-Borges, W., McNicholas, S., Wilson, K. S., Leite, L. C. C. & Wilson, R. A., 3 Mar 2021, In: Frontiers in immunology. 11, p. 624613

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2009

  Immune effector mechanisms against schistosomiasis: looking for a chink in the parasite's armour

  Wilson, R. A. & Coulson, P. S., Sept 2009, In: Trends in parasitology. 25, 9, p. 423-431 9 p.

  Research output: Contribution to journal › Literature review › peer-review
• 2008

  Altered Patterns of Gene Expression Underlying the Enhanced Immunogenicity of Radiation-Attenuated Schistosomes

  Dillon, G. P., Feltwell, T., Skelton, J., Coulson, P. S., Wilson, R. A. & Ivens, A. C., May 2008, In: PLOS NEGLECTED TROPICAL DISEASES. 2, 5, p. - 9 p., e240.

  Research output: Contribution to journal › Article › peer-review

• Antibodies elicited by the secretions from schistosome cercariae and eggs are predominantly against glycan epitopes

  Kariuki, T. M., Farah, I. O., Wilson, R. A. & Coulson, P. S., Oct 2008, In: Parasite immunology. 30, 10, p. 554-562 9 p.

  Research output: Contribution to journal › Article › peer-review

• Elimination of Schistosoma mansoni Adult Worms by Rhesus Macaques: Basis for a Therapeutic Vaccine?

  Wilson, R. A., Langermans, J. A. M., van Dam, G. J., Vervenne, R. A., Hall, S. L., Borges, W. C., Dillon, G. P., Thomas, A. W. & Coulson, P. S., Sept 2008, In: PLOS NEGLECTED TROPICAL DISEASES. 2, 9, p. - 8 p., e290.

  Research output: Contribution to journal › Article › peer-review
• 2006

  Microarray analysis identifies genes preferentially expressed in the lung schistosomulum of Schistosoma mansoni

  Dillon, G. P., Feltwell, T., Skelton, J. P., Ashton, P. D., Coulson, P. S., Quail, M. A., Nikolaidou-Katsaridou, N., Wilson, R. A. & Ivens, A. C., Jan 2006, In: International Journal for Parasitology. 36, 1, p. 18 8 p.

  Research output: Contribution to journal › Article › peer-review

• Previous or ongoing schistosome infections do not compromise the efficacy of the attenuated cercaria vaccine

  Kariuki, T. M., Van Dam, G. J., Deelder, A. M., Farah, I. O., Yole, D. S., Wilson, R. A. & Coulson, P. S., Jul 2006, In: Infection and Immunity. 74, 7, p. 3979-3986 8 p.

  Research output: Contribution to journal › Article › peer-review

• Schistosome vaccines: a critical appraisal

  Wilson, R. A. & Coulson, P. S., 2006, In: Memorias do Instituto Oswaldo Cruz. 101, p. 13-20 8 p.

  Research output: Contribution to journal › Article › peer-review

• Schistosome vaccine testing: lessons from the baboon model

  Coulson, P. S. & Kariuki, T. M., 2006, In: Memorias do Instituto Oswaldo Cruz. 101, p. 369-372 4 p.

  Research output: Contribution to journal › Article › peer-review

• 2005

  Chitinase and Fizz family members are a generalized feature of nematode infection with selective Upregulation of Ym1 and F10.1 by antigen-presenting cells

  Nair, M. G., Gallagher, L. J., Taylor, M. D., Loke, P., Coulson, P. S., Maizels, R. M., Allen, J. E. & Wilson, R. A., Jan 2005, In: Infection and Immunity. 73, 1, p. 385-394 10 p.

  Research output: Contribution to journal › Article › peer-review

  File
• 2004

  Parameters of the attenuated schistosome vaccine evaluated in the olive baboon

  Kariuki, T. M., Farah, I. O., Yole, D. S., Mwenda, J. M., Van Dam, G. J., Deelder, A. M., Coulson, P. S. & Wilson, R. A., Sept 2004, In: Infection and Immunity. 72, 9, p. 5526-5529 4 p.

  Research output: Contribution to journal › Article › peer-review

  File
• 2003

  IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni

  Linehan, S. A., Coulson, P. S., Wilson, R. A., Mountford, A. P., Brombacher, F., Martinez-Pomares, L. & Gordon, S., Aug 2003, In: Laboratory investigation. 83, 8, p. 1223-1231 9 p.

  Research output: Contribution to journal › Article › peer-review

• Juvenile rhesus monkeys have lower type 2 cytokine responses than adults after primary infection with Schistosoma mansoni

  Fallon, P. G., Gibbons, J., Vervenne, R. A., Richardson, E. J., Fulford, A. J. C., Kiarie, S., Sturrock, R. F., Coulson, P. S., Deelder, A. M., Langermans, J. A. M., Thomas, A. W. & Dunne, D. W., 15 Mar 2003, In: The Journal of Infectious Diseases. 187, 6, p. 939-945 7 p.

  Research output: Contribution to journal › Article › peer-review

• Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni

  DeMarco, R., Martins, E. A. L., Guimarães, P. E. M., Ojopi, E. P. B., Paquola, A. C. M., Piazza, J. P., Nishiyama Jr, N. Y., Kitajima, J. P., Adamson, R. E., Bonaldo, M. F., Coulson, P. S., Farias, L. P., Gregorio, S. P., Ho, P. L., Leite, R. A., Malaquias, L. C. C., Marques, R. C. P., Miyasato, P. A., Nascimento, A. L. T. O., Ohlweiler, F. P., & 17 othersReis, E. M., Ribeiro, M. A., Sá, R. G., Stukart, G. C., Soares, M. B., Gargioni, C., Kawano, T., Rodrigues, V., Madeira, A. M. B. N., Menck, C. F. M., Setubal, J. C., Leite, L. C. C., Dias-Neto, E., Verjovski-Almeida, S., Ashton, P. D., Dillon, G. P. & Wilson, R. A., Oct 2003, In: Nature genetics. 35, 2, p. 148-157 10 p.

  Research output: Contribution to journal › Article › peer-review
• 2001

  Antibodies to glycans dominate the host response to schistosome larvae and eggs: Is their role protective or subversive?

  Eberl, M., Langermans, J. A. M., Vervenne, R. A., Nyame, A. K., Cummings, R. D., Thomas, A. W., Coulson, P. S. & Wilson, R. A., 15 Apr 2001, In: The Journal of Infectious Diseases. 183, 8, p. 1238-1247 9 p.

  Research output: Contribution to journal › Article › peer-review

  File

• Cellular and humoral immune responses and protection against schistosomes induced by a radiation-attenuated vaccine in chimpanzees

  Frost, P. A., Coulson, P. S., Eberl, M., Langermans, J. A. M., Vervenne, R. A., Van Dam, G. J., Deelder, A. M., Thomas, A. W. & Wilson, R. A., Sept 2001, In: Infection and Immunity. 69, 9, p. 5352-5362 10 p.

  Research output: Contribution to journal › Article › peer-review

  File

• Signaling via interleukin-4, receptor alpha chain is required for successful vaccination against schistosomiasis in BALB/c mice

  Mountford, A. P., Coulson, P. S., Hogg, K. G. & Brombacher, F., 2001, In: Infection and Immunity. 69, 1, p. 228-236 8 p.

  Research output: Contribution to journal › Article › peer-review

  File

• The effects of chronic schistosomiasis on murine Helicobacter induced gastritis

  Crabtree, J. E., Court, M., Walker, M. M., Coulson, P. S., Coggle, S., Robinson, P. A., Sosnoskwa, D. & Telford, J. L., Apr 2001, In: Gastroenterology. 120, 5, p. A707-A707 1 p.

  Research output: Contribution to journal › Article › peer-review

• 2000

  Characterization, cloning and immunogenicity of antigens released by transforming cercariae of Schistosoma mansoni

  Jennings, N., Moutford, A. P., Coulson, P. S., Harrop, R. & Wilson, R. A., Oct 2000, In: Parasitology. 121, 4, p. 385-394 9 p.

  Research output: Contribution to journal › Article › peer-review

  File

• IL-18 potentiates the adjuvant properties of IL-12 in the induction of a strong Th1 type immune response against a recombinant antigen

  Eberl, M., Beck, E., Coulson, P. S., Okamura, H., Wilson, R. A. & Mountford, A. P., 2000, In: Vaccine. 18, 19, p. 2002-8 7 p.

  Research output: Contribution to journal › Article › peer-review

• 1999

  Characterization, cloning and immunogenicity of antigens released by lung-stage larvae of Schistosoma mansoni

  Harrop, R., Coulson, P. S. & Wilson, R. A., Jun 1999, In: Parasitology. 118, 6, p. 583-594 12 p.

  Research output: Contribution to journal › Article › peer-review

  File

• Immune responses to the radiation-attenuated schistosome vaccine: what can we learn from knock-out mice?

  Wilson, R. A., Coulson, P. S. & Mountford, A. P., Jan 1999, In: Immunology letters. 65, 1-2, p. 117-123 7 p.

  Research output: Contribution to journal › Article › peer-review

• Interleukin-12 can directly induce T-helper 1 responses in interferon-gamma (IFN-gamma) receptor-deficient mice, but requires IFN-gamma signalling to downregulate T-helper 2 responses

  Mountford, A. P., Coulson, P. S., Wynn, T. A., Cheever, A. W., Sher, A. & Wilson, R. A., Aug 1999, In: Immunology. 97, 4, p. 588-594 6 p.

  Research output: Contribution to journal › Article › peer-review

• Strategies for a schistosome vaccine: can we manipulate the immune response effectively?

  Wilson, R. A. & Coulson, P. S., Jun 1999, In: Microbes and infection. 1, 7, p. 535-543 9 p.

  Research output: Contribution to journal › Article › peer-review

• The radiation-attenuated schistosome vaccine induces high levels of protective immunity in the absence of B cells

  Anderson, S., Coulson, P. S., Ljubojevic, S., Mountford, A. P. & Wilson, R. A., Jan 1999, In: Immunology. 96, 1, p. 22-28 7 p.

  Research output: Contribution to journal › Article › peer-review

• TNF is essential for the cell-mediated protective immunity induced by the radiation-attenuated schistosome vaccine

  Street, M., Coulson, P. S., Sadler, C., Warnock, L. J., McLaughlin, D., Bluethmann, H. & Wilson, R. A., 15 Oct 1999, In: Journal of Immunology. 163, 8, p. 4489-4494 6 p.

  Research output: Contribution to journal › Article › peer-review

• 1998

  African trypanosome infections in mice that lack the interferon-gamma receptor gene: nitric oxide-dependent and -independent suppression of T-cell proliferative responses and the development of anaemia

  Mabbott, N. A., Coulson, P. S., Smythies, L. E., Wilson, R. A. & Sternberg, J. M., Aug 1998, In: Immunology. 94, 4, p. 476-480 5 p.

  Research output: Contribution to journal › Article › peer-review

• Nitric oxide produced in the lungs of mice immunized with the radiation-attenuate schistosome vaccine is not the major agent causing challenge parasite elimination

  Coulson, P. S., Smythies, L. E., Betts, C., Mabbott, N. A., Sternberg, J. M., Wei, X. G., Liew, F. Y. & Wilson, R. A., Jan 1998, In: Immunology. 93, 1, p. 55-63 9 p.

  Research output: Contribution to journal › Article › peer-review

• Schistosome-induced portacaval haemodynamic changes in Rattus rattus are associated with translocation of adult worms to the lungs

  Imbert-Establet, D., Mone, H., Coulson, P. S. & Wilson, R. A., Mar 1998, In: Parasitology. 116, 3, p. 237-241 5 p.

  Research output: Contribution to journal › Article › peer-review

  File
• 1997

  Molecular analysis of the interaction between HPV type 16 E6 and human E6-associated protein

  Daniels, P. R., Sanders, C. M., Coulson, P. & Maitland, N. J., 13 Oct 1997, In: FEBS Letters. 416, 1, p. 610 5 p.

  Research output: Contribution to journal › Article › peer-review

• Recruitment of lymphocytes to the lung through vaccination enhances the immunity of mice expose to irradiated schistosomes

  Coulson, P. S. & Wilson, R. A., Jan 1997, In: Infection and Immunity. 65, 1, p. 42-48 7 p.

  Research output: Contribution to journal › Article › peer-review

• The radiation-attenuated vaccine against schistosomes in animal models: Paradigm for a human vaccine?

  Coulson, P. S., 1997, ADVANCES IN PARASITOLOGY, VOL 39. SAN DIEGO: Elsevier, p. 271-336 66 p.

  Research output: Chapter in Book/Report/Conference proceeding › Other chapter contribution

• 1996

  Impaired immunity and altered pulmonary responses in mice with a disrupted interferon-gamma receptor gene exposed to the irradiated Schistosoma mansoni vaccine

  Wilson, R. A., Coulson, P. S., Betts, C., Dowling, M. A. & Smythies, L. E., Feb 1996, In: Immunology. 87, 2, p. 275-282 8 p.

  Research output: Contribution to journal › Article › peer-review

• Kinetics and mechanism of effector focus formation in the lungs of mice vaccinated with irradiated cercariae of Schistosoma mansoni

  Smythies, L. E., Betts, C., Coulson, P. S., Dowling, M. A. & Wilson, R. A., Jul 1996, In: Parasite immunology. 18, 7, p. 359-369 11 p.

  Research output: Contribution to journal › Article › peer-review

• 1994

  A MODEL SYSTEM FOR THE STUDY OF ANTIGEN SECRETION BY ADULT SCHISTOSOMA-MANSONI IN-VIVO

  Saunders, N., Coulson, P. S., Wilson, R. A., Dejonge, N., Krijger, F. W. & Deelder, M., Feb 1994, In: Parasitology research. 80, 2, p. 154-158 5 p.

  Research output: Contribution to journal › Article › peer-review

• HEPATIC RECRUITMENT OF MAST-CELLS OCCURS IN RATS BUT NOT MICE INFECTED WITH SCHISTOSOMA-MANSONI

  Miller, H. R. P., Newlands, G. F. J., McKellar, A., Inglis, L., Coulson, P. S. & Wilson, R. A., Mar 1994, In: Parasite immunology. 16, 3, p. 145-155 11 p.

  Research output: Contribution to journal › Article › peer-review

• 1993

  FUNCTIONAL AND PHENOTYPIC PROPERTIES OF THE CD4+ T-CELL POPULATION IN A MURINE PULMONARY DELAYED-TYPE HYPERSENSITIVITY RESPONSE

  Coulson, P. S., Smythies, L. E. & Wilson, R. A., Feb 1993, In: Chest. 103, 2, p. S138-S138 1 p.

  Research output: Contribution to journal › Article › peer-review

• IMMUNITY TO SCHISTOSOMA-MANSONI IN MICE VACCINATED WITH IRRADIATED CERCARIAE - CYTOKINE INTERACTIONS IN THE PULMONARY PROTECTIVE RESPONSE

  Smythies, L. E., Coulson, P. S. & Wilson, R. A., Dec 1993, In: Annals of tropical medicine and parasitology. 87, 6, p. 653-657 5 p.

  Research output: Contribution to journal › Article › peer-review

• PHENOTYPIC AND FUNCTIONAL-PROPERTIES OF TH LINES AND CLONES RECOGNIZING LARVAL ANTIGENS OF SCHISTOSOMA-MANSONI

  Pemberton, R. M., Coulson, P. S., Smythies, L. E. & Wilson, R. A., Jul 1993, In: Parasite immunology. 15, 7, p. 373-382 10 p.

  Research output: Contribution to journal › Article › peer-review

• PULMONARY T-HELPER LYMPHOCYTES ARE CD44(HI), CD45RB- EFFECTOR MEMORY CELLS IN MICE VACCINATED WITH ATTENUATED CERCARIAE OF SCHISTOSOMA-MANSONI

  Coulson, P. S. & Wilson, R. A., 1 Oct 1993, In: Journal of Immunology. 151, 7, p. 3663-3671 9 p.

  Research output: Contribution to journal › Article › peer-review

• 1992

  CROSS-REACTIVITY BETWEEN NECATOR-AMERICANUS AND SCHISTOSOMA-MANSONI IN MICE

  Timothy, L. M., Coulson, P. S., Behnke, J. M. & Wilson, R. A., Dec 1992, In: International Journal for Parasitology. 22, 8, p. 1143-1149 7 p.

  Research output: Contribution to journal › Article › peer-review

• MONOCLONAL-ANTIBODY TO IFN-GAMMA MODIFIES PULMONARY INFLAMMATORY RESPONSES AND ABROGATES IMMUNITY TO SCHISTOSOMA-MANSONI IN MICE VACCINATED WITH ATTENUATED CERCARIAE

  Smythies, L. E., Coulson, P. S. & Wilson, R. A., 1 Dec 1992, In: Journal of Immunology. 149, 11, p. 3654-3658 5 p.

  Research output: Contribution to journal › Article › peer-review

• T cell-derived cytokines associated with pulmonary immune mechanisms in mice vaccinated with irradiated cercariae of Schistosoma mansoni

  Smythies, L. E., Pemberton, R. M., Coulson, P. S., Mountford, A. P. & Wilson, R. A., 1992, In: Journal of Immunology. 148, 5, p. 1512-8 7 p.

  Research output: Contribution to journal › Article › peer-review

• THE GENERATION OF INTERFERON-GAMMA-PRODUCING LYMPHOCYTES-T IN SKIN-DRAINING LYMPH-NODES, AND THEIR RECRUITMENT TO THE LUNGS, IS ASSOCIATED WITH PROTECTIVE IMMUNITY TO SCHISTOSOMA-MANSONI

  Mountford, A. P., Coulson, P. S., Pemberton, R. M., Smythies, L. E. & Wilson, R. A., Feb 1992, In: Immunology. 75, 2, p. 250-256 7 p.

  Research output: Contribution to journal › Article › peer-review

• 1990

  IMMUNE ELIMINATION OF SCHISTOSOMES - REPLY

  Wilson, R. A. & Coulson, P. S., Feb 1990, In: Parasitology today. 6, 2, p. 37-37 1 p.

  Research output: Contribution to journal › Letter › peer-review

• SCHISTOSOME MIGRATION IN PRIMATES - A STUDY IN THE OLIVE BABOON (PAPIO-ANUBIS)

  Wilson, R. A., Coulson, P. S., Sturrock, R. F. & Reid, G. D. F., 1990, In: Transactions of the royal society of tropical medicine and hygiene. 84, 1, p. 80-83 4 p.

  Research output: Contribution to journal › Article › peer-review

• 1989

  CHARACTERISTICS OF PROTECTIVE IMMUNITY IN MICE INDUCED BY DRUG-ATTENUATED LARVAE OF SCHISTOSOMA-MANSONI - ANTIGEN LOCALIZATION AND ANTIBODY-RESPONSES

  Mountford, A. P., Coulson, P. S., Saunders, N. & Wilson, R. A., 1 Aug 1989, In: Journal of Immunology. 143, 3, p. 989-995 7 p.

  Research output: Contribution to journal › Article › peer-review

• FATE OF ATTENUATED SCHISTOSOMULA ADMINISTERED TO MICE BY DIFFERENT ROUTES, RELATIVE TO THE IMMUNITY INDUCED AGAINST SCHISTOSOMA-MANSONI

  Coulson, P. S. & Mountford, A. P., Aug 1989, In: Parasitology. 99, p. 39-45 7 p.

  Research output: Contribution to journal › Article › peer-review

• LUNG-PHASE IMMUNITY TO SCHISTOSOMES - A NEW PERSPECTIVE ON AN OLD PROBLEM

  Wilson, R. A. & Coulson, P. S., Sept 1989, In: Parasitology today. 5, 9, p. 274-278 5 p.

  Research output: Contribution to journal › Article › peer-review

• PORTAL SHUNTING AND RESISTANCE TO SCHISTOSOMA-MANSONI IN 129 STRAIN MICE

  Coulson, P. S. & Wilson, R. A., Dec 1989, In: Parasitology. 99, p. 383-389 7 p.

  Research output: Contribution to journal › Article › peer-review