Peter Andrew O'Brien — York Research Database

Phone(01904) 322535
Emailpeter.obrienyork.acuk

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131 Article
3 Review article
2 Chapter
2 Literature review
More
- 1 Editorial
- 1 Preprint

Escape from planarity in fragment-based drug discovery: A synthetic strategy analysis of synthetic 3D fragment libraries
Klein, H. F., Hamilton, D. J., de Esch, I. J. P., Wijtmans, M. & O'Brien, P., Sep 2022, In: Drug discovery today. 27, 9, p. 2484-2496
Research output: Contribution to journal › Review article › peer-review

Open Access
File
Organolithium Gels – Simple Easily Divided Delivery Vehicles for Highly Reactive Species
Slavik, P., O'Brien, P. A. & Smith, D. K., 18 Feb 2022, (E-pub ahead of print) ChemRxiv, 11 p.
Research output: Working paper › Preprint

File
Puckering the Planar Landscape of Fragments: Design and Synthesis of a 3D Cyclobutane Fragment Library
Hamilton, D. J., Beemsterboer, M., Carter, C. M., Elsayed, J., Huiberts, R. E. M., Klein, H. F., O'Brien, P., de Esch, I. J. P. & Wijtmans, M., 4 May 2022, In: ChemMedChem. 17, 9, 9 p., e202200113.
Research output: Contribution to journal › Article › peer-review

Open Access
File

2 Active
8 Finished

Stereospecific Csp3-Csp2 Cross-Coupling of Heterocyclic Alkyl Borona_A Transformative Disconnection for Drug Discovery
O'Brien, P. A. & Fairlamb, I. J. S.
EPSRC
1/05/21 → 30/04/23
Project: Research project (funded) › Research
Modular Approach for Elaborating Fragments to 3-D Lead Compounds for Drug Discovery: Bifunctional 3-D Building Blocks with Distinct 3-D Vectors
O'Brien, P. A.
THE ROYAL SOCIETY
1/07/19 → 30/06/23
Project: Research project (funded) › Research
EPSRC IAA 3D Building Blocks for the Pharmaceutical Industry via Partnering with Redbrick Molecular
O'Brien, P. A.
EPSRC
1/08/19 → 31/10/19
Project: Other project (funded) › Restricted grant

Invited speaker, RSC Synthesis in Drug Discovery and Deveopment Symposium - virtual event
Peter Andrew O'Brien (Invited speaker)
22 Mar 2021 → 23 Mar 2021
Activity: Talk or presentation › Symposium
Invited Lecture, Pfizer
Peter Andrew O'Brien (Keynote/plenary speaker)
8 Dec 2020
Activity: Talk or presentation › Webinar
Organising Committee, RSC Organic Division Poster Symposium 2020 - virtual event
Peter Andrew O'Brien (Member of programme committee)
30 Nov 2020
Activity: Participating in or organising an event › Symposium

Raw data for the paper 'Catalyst-Driven Scaffold Diversity: Selective Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones'
Unsworth, W. P. (Creator), Taylor, R. J. K. (Contributor), O'Brien, P. A. (Contributor), Liddon, J. T. R. (Contributor), Clarke, A. (Contributor) & James, M. J. (Contributor), University of York, 3 May 2017
DOI: 10.15124/791ce678-7d32-47d5-9445-2f4813d22425, https://pure.york.ac.uk/portal/files/70200858/RAW_DATA_JOHN_LIDDON_2016_CEJ.zip and one more link, https://creativecommons.org/licenses/by/4.0/ (show fewer)
Dataset
Data underpinning Design and Synthesis of 56 Shape Diverse 3‐D Fragments
O'Brien, P. A. (Creator), Firth, J. (Contributor) & Klein, H. (Contributor), University of York, 2020
DOI: 10.15124/56e2e1ac-32ae-4753-8ef1-320d41b0c4d7, https://pure.york.ac.uk/portal/files/69889478/DropOff_qNxfWHWR4eFRy7Y8.zip and one more link, https://creativecommons.org/licenses/by/4.0/ (show fewer)
Dataset
Synthesis of Enantiopure Piperazines via Asymmetric Lithiation-Trapping of N-Boc Piperazines: Unexpected Role of the Electrophile and Distal N-Substituent Dataset
O'Brien, P. A. (Creator), University of York, 5 Jan 2016
DOI: 10.15124/04a01ef8-f5aa-4f78-8db1-9c02e3945e69, https://pure.york.ac.uk/portal/files/69909022/NMR_Data.zip and one more link, https://creativecommons.org/licenses/by/4.0/ (show fewer)
Dataset

York University Student's Union (YUSU) Teacher of the Year
O'Brien, Peter Andrew (Recipient), 4 Jun 2019
Prize: Prize (including medals and awards)
RSC Organic Stereochemistry Award
O'Brien, Peter Andrew (Recipient), May 2013
Prize: Prize (including medals and awards)
2017 AstraZeneca, GlaxoSmithKline, Pfizer & Syngenta prize for Process Chemistry Research
O'Brien, Peter Andrew (Recipient), Mar 2017
Prize: Prize (including medals and awards)