RODERICK HUBBARD

Design, Modular Synthesis and Screening of 58 Shape-Diverse 3-D Fragments
DOWNES, T., JONES, P., FIRTH, J., DARBY, J. F., GILIO, A., KLEIN, H. F., WANG, X., Blakemore, D. C., De Fusco, C., Roughley, S., Vidler, L. R., Whatton, M. A., Woolford, A.J.-A., Wrigley, G. L., Hubbard, R. E., WU, L., DAVIES, G. J. & O'BRIEN, P. A., 14 Nov 2025, In: Chemical Science. 16, p. 20030-20041 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Identification of a Novel Subtype-Selective α_1B-Adrenoceptor Antagonist
Abdul-Ridha, A., de Zhang, L. A., Betrie, A. H., Deluigi, M., Vaid, T. M., Whitehead, A., Zhang, Y., Davis, B., Harris, R., Simmonite, H., Hubbard, R. E., Gooley, P. R., Plückthun, A., Bathgate, R. A. D., Chalmers, D. K. & Scott, D. J., 7 Feb 2024, In: ACS Chemical Neuroscience. 15, 3, p. 671–684
Research output: Contribution to journal › Article › peer-review
Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors
FitzGerald, E. A., Vagrys, D., Opassi, G., Klein, H. F., Hamilton, D. J., Talibov, V. O., Abramsson, M., Moberg, A., Lindgren, M. T., Holmgren, C., Davis, B., O'Brien, P., Wijtmans, M., Hubbard, R. E., de Esch, I. J. P. & Danielson, U. H., 14 Sept 2023, In: SLAS Discovery. 12 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

Fragment-based activation and modification of industrial enzymes
HUBBARD, R. (Principal investigator), DARBY, J. (Co-investigator), DAVIES, G. (Co-investigator) & O'BRIEN, P. (Co-investigator)
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
29/04/16 → 28/08/19
Project: Research project (funded) › Research
Fragments Training Network (H2020-MSCA-ITN-2015)
HUBBARD, R. (Principal investigator)
EUROPEAN COMMISSION
1/03/16 → 29/02/20
Project: Research project (funded) › Research
C2D2 Research 3a - Small molecule manipulation of microRNA biogenesis: application to microRNAs linked to chronic diseases
PLEVIN, M. (Principal investigator), ANTSON, F. (Co-investigator), HUBBARD, R. (Co-investigator) & LAGOS, D. (Co-investigator)
1/02/14 → 31/12/14
Project: Other project › Other internal award

One day conference during EU workshop
Hubbard, R. E. (Invited speaker)
18 Jun 2019
Activity: Participating in or organising an event › Seminar/workshop/course
Small becomes big - Fragment based discovery
Hubbard, R. E. (Invited speaker) & Hubbard, R. E. (Presenter)
28 Apr 2019 → 1 May 2019
Activity: Participating in or organising an event › Seminar/workshop/course
EMBL EBI (External organisation)
Hubbard, R. E. (Advisor)
26 Apr 2019 → 28 Apr 2019
Activity: Membership › Board

Collaborations and top research areas from the last five years