Stephen Derek Brealey

Search results

• 2023

  Examination of early treatment effects and related biases during the conduct of two UK-wide pragmatic orthopaedic surgical trials: ProFHER and UK FROST

  Knowlson, C., Brealey, S. D., Keding, A., Torgerson, D. J. & Rangan, A., 14 Feb 2023, In: Bone & Joint Open. 4, 2, p. 96-103 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2022

  Expert clinical consensus in the delivery of hydrodilatation for the management of patients with a primary frozen shoulder

  Thompson, H., Brealey, S. D., Cook, L., Hadi, S., Khan, S. HM. & Rangan, A., 2 Sept 2022, In: Bone & Joint Open. 3, 9, p. 701-709 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Mapping the Oxford Shoulder Score onto the EQ‑5D utility index

  Valsamis, E., Beard, D., Carr, A., Collins, G., Brealey, S. D., Rangan, A., Santos, R., Corbacho Martín, B., Rees, J. & Pinedo‑Villanueva, R., 28 Sept 2022, (E-pub ahead of print) In: Quality of life research. 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• One year outcome of surgery versus cast immobilisation for adults with an acute undisplaced or minimally displaced scaphoid fracture: A meta-analysis of randomised controlled trials

  Johnson, N., Fairhurst, C. M., Brealey, S. D., Cook, L., Stirling, E., Costa, M., Divall, P., Hodgson, S., Rangan, A. & Dias, J., 1 Aug 2022, In: The Bone and Joint journal. 104-B, 8, p. 953-962 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Patient Experiences of Scaphoid Waist Fractures and their Treatment: a Qualitative Investigation

  Leighton, P., Brealey, S. D. & Dias, J., 15 Aug 2022, In: Bone & Joint Open. 3, 8, p. 641–647 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Recruitment patterns in multicentre randomised trials fit more closely to Price's Law than the Pareto Principle: A review of trials funded and published by the United Kingdom Health Technology Assessment Programme

  Knowlson, C. N., Dean, A., Doherty, L., Fairhurst, C. M., Brealey, S. D. & Torgerson, D. J., 1 Feb 2022, In: Contemporary Clinical Trials. 113, 10 p., 106665.

  Research output: Contribution to journal › Article › peer-review

• Staff training to improve participant recruitment into surgical randomised controlled trials: a feasibility Study Within A Trial (SWAT) across four host randomised controlled trials simultaneously

  Parker, A., Arundel, C. E., Mills, N., Rooshenas, L., Jepson, M., Donovan, JL., Blazeby, JM., Coleman, E., Clark, L. K., Doherty, L., Hewitt, C. E., Partha Sarathy, P., Beard, D., Bower, P., Brealey, S. D., Brocklehurst, P., Cooper, C., Croft, J., Culliford, L., Dias, J., & 13 othersDevane, D., Eldridge, S., Emsley, R., Galvin, S., Gemperle-Mannion, E., Jayne, D., Metcalfe, A., Montgomery, A., Rangan, A., Sutton, C., Tharmanathan, P., Treweek, S. & Torgerson, D. J., 15 Jun 2022, (E-pub ahead of print) In: Research Methods in Medicine & Health Sciences. 14 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2021

  A multicentre, randomised, parallel group, superiority study to compare the clinical and cost-effectiveness of external frame versus internal locking plate for complete articular pilon fracture fixation in adults: protocol for the ACTIVE randomised controlled trial

  Flett, L. G., Adamson, J. A., Barron, E., Brealey, S. D., Corbacho Martín, B., Costa, M. L., Gedney, G., Giotakis, N., Hewitt, C. E., Hugill-Jones, J., Hukins, D., Keding, A., McDaid, C. M., Mitchell, A. S., Northgraves, M., O'Carroll, G., Parker, A., Scantlebury, A. L., Stobbart, L., Torgerson, D. J., & 3 othersTurner, E., Welch, C. & Sharma, H., 5 Mar 2021, (E-pub ahead of print) In: Bone & Joint Open. 2, 3, p. 1-13 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Cost-effective clinical trial design: application of a Bayesian sequential model to the ProFHER pragmatic trial

  Forster, M., Brealey, S. D., Chick, S., Keding, A., Corbacho Martín, B., Alban, A., Pertile, P. & Rangan, A., 1 Dec 2021, In: Clinical trials. 18, 6, p. 647-656 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Cost-effectiveness of surgery versus cast immobilization for adults with a bi-cortical fracture of the scaphoid waist: a within trial economic evaluation of the SWIFFT trial

  Hinde, S., Richardson, G., Fairhurst, C. M., Brealey, S. D., Cook, L., Rangan, A., Costa, M. & Dias, J., 1 Jul 2021, (E-pub ahead of print) In: The Bone and Joint journal. 103-B, 7, p. 1277–1283 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Cost-effectiveness of surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder: economic evaluation of UK FROST trial

  Corbacho Martín, B., Brealey, S. D., Keding, A., Richardson, G., Torgerson, D. J., Hewitt, C. E., McDaid, C. M. & Rangan, A., 2 Aug 2021, In: Bone & Joint Open. 2, 8, p. 685-695 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Effectiveness of interventions for the management of primary frozen shoulder: A systematic review of randomised trials

  Rex, S., Kottam, L., McDaid, C. M., Brealey, S. D., Dias, J., Hewitt, C. E., Keding, A., Lamb, S. E., Wright, K. & Rangan, A., 3 Jun 2021, (Accepted/In press) In: Bone & Joint Open.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Embedding qualitative research in randomised controlled trials to improve recruitment: findings from two recruitment optimisation studies of orthopaedic surgical trials

  Scantlebury, A. L., McDaid, C. M., Brealey, S. D., Cook, L., Ranganathan, A., Sharma, H. & Adamson, J. A., 17 Jul 2021, In: Trials.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2020

  Concerns about the evidence in relation to implementation of the ProFHER trial

  Handoll, H., Brealey, S. & Rangan, A., 10 Feb 2020, In: BMJ Quality & Safety. 29, 5, p. 430-431 2 p.

  Research output: Contribution to journal › Comment/debate › peer-review

• Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial

  UK FROST Study Group, 3 Oct 2020, In: The Lancet. 396, 10256, p. 977-989 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Scaphoid Waist Internal Fixation for Fractures Trial (SWIFFT): a randomised controlled trial, economic evaluation and nested qualitative study of cast versus surgical fixation for the treatment of adult patients with a bi-cortical fracture of the scaphoid waist

  Dias, J., Brealey, S. D., Cook, E., Fairhurst, C. M., Hinde, S., Leighton, P., Choudhary, S., Costa, M., Hewitt, C. E., Hodgson, S., Jefferson, L. A., Jeyapalan, K., Keding, A., Northgraves, M., Palmer, J., Rangan, A., Richardson, G. A., Taub, N., Tew, G. A., Thompson, J., & 1 othersTorgerson, D. J., Oct 2020, In: Health technology assessment. 24, 52, p. 1-141 142 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Surgery versus cast immobilisation for adults with a bicortical fracture of the scaphoid waist (SWIFFT): a pragmatic, multicentre, open-label, randomised superiority trial

  Dias, J., Brealey, S. D., Fairhurst, C. M., Amirfeyz, R., Bhowal, B., Blewitt, N., Brewster, M., Brown, D., Choudhary, S., Coapes, C., Cook, L., Costa, M., Davis, T., DisMascio, L., Giddins, G., Hedley, H., Hewitt, C. E., Hinde, S., Jonathan, H., Hodgson, S., & 26 othersJefferson, L. A., Jeyapalan, K., Johnston, P., Jones, J., Keding, A., Leighton, P., Logan, A., Mason, W., McAndrew, A., McNab, I., Muir, L., Nicholl, J., Northgraves, M., Palmer, J., Poulter, R., Rahimtoola, Z., Rangan, A., Richards, S., Richardson, G., Stuart, P., Taub, N., Tavakkolizadeh, A., Tew, G. A., Thompson, J., Torgerson, D. J. & Warwick, D., 6 Aug 2020, (E-pub ahead of print) In: The Lancet. 396, 10248, p. 390-401 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Timing of electronic reminders did not improve trial participant questionnaire response: a randomized trial and meta-analyses

  Sarathy, P. P., Kottam, L., Parker, A., Brealey, S., Coleman, E., Keding, A., Mitchell, A., Northgraves, M., Torgerson, D. & Rangan, A., Jun 2020, In: Journal of Clinical Epidemiology. 122, p. 70-77 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2019

  Cost-Effective Clinical Trial Design: Application of a Bayesian Sequential Stopping Rule to the ProFHER Pragmatic Trial

  Forster, M., Brealey, S. D., Chick, S., Keding, A., Corbacho Martin, M. B., Alban, A. & Rangan, A., 8 Feb 2019.

  Research output: Working paper › Discussion paper

• Does time to surgery affect patient-reported outcome in proximal humeral fractures? A subanalysis of the PROFHER randomized clinical trial

  Norman, J., Brealey, S. D., Keding, A., Torgerson, D. J. & Rangan, A., 31 Dec 2019, In: The Bone and Joint journal. 102-B, 1, p. 31-41 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Physiotherapy for primary frozen shoulder in secondary care: Developing and implementing stand-alone and post-operative protocols for UK FROST and inferences for wider practice

  Hanchard, NCA., Goodchild, L., Brealey, S. D., Lamb, SE. & Rangan, A., 19 Jul 2019, (E-pub ahead of print) In: Physiotherapy .

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• The impact of surgeon and patient treatment preferences in an orthopaedic trauma surgery trial

  Keding, A., Handoll, H., Brealey, S. D., Jefferson, L. A., Hewitt, C. E., Corbacho, B., Torgerson, D. J. & Rangan, A., 18 Sept 2019, (E-pub ahead of print) In: Trials. 20, 570 (2019).

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Tissue inflammation signatures point towards resolution in adhesive capsulitis

  Dakin, SG., Rangan, A., Martinez, F., Brealey, S. D., Northgraves, M., Kottam, L., Cooper, C., Buckley, CD. & AJ, C., 28 Jan 2019, In: Rheumatology. 58, 6, p. 1109-1111 3 p.

  Research output: Contribution to journal › Article

  Open Access

  File
• 2018

  Interventions to improve retention in a surgical, clinical trial: A pragmatic, stakeholder-driven approach

  Leighton, P. A., Brealey, S. D. & Dias, J., 22 Jan 2018, (E-pub ahead of print) In: Evid Based Med.. 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Remote or on-site visits were feasible for the initial setup meetings with hospitals in a multicenter surgical trial: an embedded randomized trial

  Jefferson, L. A., Fairhurst, C. M., Brealey, S. D., Coleman, I., Cook, E., Hewitt, C. E., Keding, A., Northgraves, M., Rangan, A., Tew, G., Torgerson, D. J. & Dias, J., 1 Aug 2018, In: Journal of Clinical Epidemiology. 100, p. 13-21 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2017

  Five-year follow-up results of the PROFHER trial comparing operative and non-operative treatment of adults with a displaced fracture of the proximal humerus

  Handoll, H. H., Keding, A., Corbacho, B., Brealey, S. D., Hewitt, C. & Rangan, A., 1 Mar 2017, In: Bone and Joint Journal. 99-B, 3, p. 383-392 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Impact of the PROFHER trial findings on surgeons' clinical practice: An online questionnaire survey

  Jefferson, L., Brealey, S., Handoll, H. H. G., Keding, A., Kottam, L., Sbizzera, I. & Rangan, A., 24 Oct 2017, In: Bone & Joint Research. 6, 10, p. 590-599 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• United Kingdom Frozen Shoulder Trial (UK FROST), multi-centre, randomised, 12 month, parallel group, superiority study to compare the clinical and cost-effectiveness of Early Structured Physiotherapy versus manipulation under anaesthesia versus arthroscopic capsular release for patients referred to secondary care with a primary frozen shoulder: study protocol for a randomised controlled trial

  Brealey, S., Armstrong, A. L., Brooksbank, A., Carr, A. J., Charalambous, C. P., Cooper, C., Corbacho Martín, B., Dias, J., Donnelly, I., Goodchild, L., Hewitt, C., Keding, A., Kottam, L., Lamb, S. E., McDaid, C., Northgraves, M., Richardson, G., Rodgers, S., Shah, S., Sharp, E., & 4 othersSpencer, S., Torgerson, D., Toye, F. & Rangan, A., 22 Dec 2017, In: Trials. 18, 1, 15 p., 614.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2016

  'Away Days' in multi-centre randomised controlled trials: a questionnaire survey of their use and a case study on the effect of one Away Day on patient recruitment

  Jefferson, L., Cook, L., Keding, A., Brealey, S., Handoll, H. & Rangan, A., 1 Feb 2016, In: Journal of Evidence-Based Medicine. 9, 1, p. 24-31

  Research output: Contribution to journal › Article › peer-review

• Cost effectiveness of surgical versus non-surgical treatment of adults with displaced fractures of the proximal humerus: economic evaluation alongside the PROFHER trial

  Corbacho Martin, M. B., Duarte, A. I., Keding, A., Handoll, H., Chuang, L-H., Torgerson, D. J., Brealey, S. D., Jefferson, L. A., Hewitt, C. E. & Rangan, A., 5 Feb 2016, In: Bone and Joint Journal. 98, B, p. 152-159 8 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Defining the fracture population in a pragmatic multicentre randomised controlled trial: PROFHER and the Neer classification of proximal humeral fractures

  Handoll, H. H. G., Brealey, S. D., Jefferson, L., Keding, A., Brooksbank, A. J., Johnstone, A. J., Candal-Couto, J. J. & Rangan, A., 18 Oct 2016, (E-pub ahead of print) In: Bone & Joint Research. 5, 10, p. 481-489 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Scaphoid Waist Internal Fixation for Fractures Trial (SWIFFT) protocol: a pragmatic multi-centre randomised controlled trial of cast treatment versus surgical fixation for the treatment of bi-cortical, minimally displaced fractures of the scaphoid waist in adults

  Dias, J., Brealey, S., Choudhary, S., Cook, L., Costa, M., Fairhurst, C., Hewitt, C., Hodgson, S., Jefferson, L., Jeyapalan, K., Keding, A., Leighton, P., Rangan, A., Richardson, G., Rothery, C., Taub, N., Thompson, J. & Torgerson, D., 4 Jun 2016, In: BMC Musculoskeletal Disorders. 17, 1, p. 1-15 15 p., 17.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File
• 2015

  Surgical vs nonsurgical treatment of adults with displaced fractures of the proximal humerus: the PROFHER randomized clinical trial

  Rangan, A., Handoll, H., Brealey, S., Jefferson, L., Keding, A., Corbacho Martín, B., Goodchild, L., Chuang, L-H., Hewitt, C., Torgerson, D. & PROFHER Trial Collaborators, 10 Mar 2015, In: Journal of the American Medical Association. 313, 10, p. 1037-1047 11 p.

  Research output: Contribution to journal › Article › peer-review

• The ProFHER (PROximal Fracture of the Humerus Evaluation by Randomisation) trial: - a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical compared with non-surgical treatment for proximal fracture of the humerus in adults

  Handoll, H., Brealey, S., Rangan, A., Keding, A., Corbacho Martín, B., Jefferson, L., Chuang, L-H., Goodchild, L., Hewitt, C. & Torgerson, D., 31 Mar 2015, In: Health technology assessment. 19, 24, p. 1-280 281 p.

  Research output: Contribution to journal › Article › peer-review
• 2014

  Cost-Effectiveness Analysis of Acupuncture, Counselling and Usual Care in Treating Patients with Depression: The Results of the ACUDep Trial

  Spackman, E., Richmond, S., Sculpher, M., Bland, M., Brealey, S., Gabe, R., Hopton, A., Keding, A., Lansdown, H., Perren, S., Torgerson, D., Watt, I. & MacPherson, H., 26 Nov 2014, In: PLoS ONE. 9, 11, 12 p., e113726.

  Research output: Contribution to journal › Article › peer-review

• Developing, delivering and documenting rehabilitation in a multi-centre randomised controlled surgical trial: experiences from the ProFHER trial

  Handoll, H., Goodchild, L., Brealey, S. D., Hanchard, N., Jefferson, L. A., Keding, A. & Rangan, A., Dec 2014, In: Bone & Joint Research. 3, 12, p. 335-340 6 p.

  Research output: Contribution to journal › Article › peer-review

• Exploring the outcomes in studies of primary frozen shoulder: is there a need for a core outcome set?

  Rodgers, S. A., Brealey, S., Jefferson, L. A., McDaid, C. M., Maund, E., Hanchard, N., Goodchild, L. & Spencer, S., Nov 2014, In: Quality of life research. 23, 9, p. 2495-2504

  Research output: Contribution to journal › Article › peer-review

• Patients’ preferences for the management of knee injuries: a discrete choice experiment

  Chuang, L-H., Robling, M., Brealey, S. D., Bryan, S. & Hood, K., 2014, In: European Journal for Person Centered Healthcare. 2, 4, p. 439-447 9 p.

  Research output: Contribution to journal › Article › peer-review

• 2013

  Acupuncture and counselling for depression in primary care: a randomised controlled trial

  MacPherson, H., Richmond, S. J., Bland, M., Brealey, S. D., Gabe, R., Hopton, A. K., Keding, A., Lansdown, H., Perren, S., Sculpher, M., Spackman, E., Torgerson, D. J. & Watt, I., 24 Sept 2013, In: Plos medicine. 10, 9, 13 p., 1001518.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Comparative responsiveness and minimal change of the Knee Quality of Life 26-item (KQoL-26) questionnaire

  Chuang, L-H., Garratt, A. & Brealey, S., 7 Mar 2013, In: Quality of life research. Early Online, n/a, p. 1-15 15 p.

  Research output: Contribution to journal › Article › peer-review

• Diagnostic accuracy of radiographer reporting of computed tomography colonography examinations: a systematic review

  Meertens, R., Brealey, S., Nightingale, J. & McCoubrie, P., Apr 2013, In: Clinical Radiology. 68, 4, p. e177-e190

  Research output: Contribution to journal › Article › peer-review

• Observer agreement in the reporting of knee and lumbar spine magnetic resonance (MR) imaging examinations: Selectively trained MR radiographers and consultant radiologists compared with an index radiologist

  Brealey, S. D., Piper, K., King, D., Bland, M., Caddick, J., Campbell, P., Gibbon, A., Highland, A., Jenkins, N., Petty, D. & Warren, D., Oct 2013, (Accepted/In press) In: European journal of radiology. 82, 10, p. e597-e605

  Research output: Contribution to journal › Article › peer-review

• 2012

  Management of frozen shoulder: A systematic review and cost-effectiveness analysis

  Maund, E., Craig, D., Suekarran, S., Neilson, A., Wright, K., Brealey, S., Dennis, L., Goodchild, L., Hanchard, N., Rangan, A., Richardson, G., Robertson, J. & McDaid, C., Mar 2012, In: Health technology assessment. 16, 11, p. 1-264 264 p.

  Research output: Contribution to journal › Article › peer-review

• Orthopaedic Trial Networks

  Rangan, A., Brealey, S. D. & Carr, A., 18 Jul 2012, In: The Journal of Bone and Joint Surgery. 04, Suppl 1(E), p. 97-100 4 p.

  Research output: Contribution to journal › Article › peer-review

• The effect of waiting times from general practitioner referral to MRI or orthopaedic consultation for the knee on patient-based outcomes

  Brealey, S., Andronis, L., Dale, V., Gibbon, A., Gilbert, F., Hendry, M., Hood, K., King, D., Wilkinson, C. & on behalf of the DAMASK Trial Team, Nov 2012, In: The British Journal of Radiology. 85, 1019, p. e1134-e1139

  Research output: Contribution to journal › Article › peer-review
• 2011

  The effectiveness of behavioural therapy for the treatment of depression in older adults: a meta-analysis

  Samad, Z., Brealey, S. & Gilbody, S., Dec 2011, In: International journal of geriatric psychiatry. 26, 12, p. 1211-20 10 p.

  Research output: Contribution to journal › Article › peer-review
• 2010

  Instruments to identify post-natal depression: Which methods have been the most extensively validated, in what setting and in which language?

  Hewitt, C. E., Gilbody, S. M., Mann, R. & Brealey, S., Mar 2010, In: International journal of psychiatry in clinical practice. 14, 1, p. 72-U82 9 p.

  Research output: Contribution to journal › Article › peer-review

• Managing idiopathic frozen shoulder: a survey of health professionals' current practice and research priorities

  Dennis, L. A., Brealey, S. D., Rangan, A., Rookmoneea, M. & Watson, J., 2010, In: Shoulder and Elbow.

  Research output: Contribution to journal › Article › peer-review

• Participants' preference for type of leaflet used to feed back the results of a randomised trial: a survey

  Brealey, S., Andronis, L., Dennis, L., Atwell, C., Bryan, S., Coulton, S., Cox, H., Cross, B., Fylan, F., Garratt, A., Gilbert, F., Gillan, M., Hendry, M., Hood, K., Houston, H., King, D., Morton, V., Robling, M., Russell, I. & Wilkinson, C., 1 Dec 2010, In: Trials. 11, p. 116 116.

  Research output: Contribution to journal › Article › peer-review

• Screening for postnatal depression - is it acceptable to women and healthcare professionals? A systematic review and meta-synthesis

  Brealey, S. D., Hewitt, C., Green, J. M., Morrell, J. & Gilbody, S., Nov 2010, In: Journal of reproductive and infant psychology. 28, 4, p. 328-344 17 p.

  Research output: Contribution to journal › Literature review › peer-review