Vladimir Levdikov

Search results

• 2019

  Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027

  Daou, N., Wang, Y., Levdikov, V. M., Nandakumar, M., Livny, J., Bouillaut, L., Blagova, E., Zhang, K., Belitsky, B. R., Rhee, K., Wilkinson, A. J., Sun, X. & Sonenshein, A. L., 30 Jan 2019, In: PLoS ONE. 14, 1, 34 p., e0206896.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Structural and functional analysis of the nucleotide and DNA binding activities of the human PIF1 helicase

  Dehghani-Tafti, S., Levdikov, V., Antson, A. A., Bax, B. & Sanders, C. M., 8 Apr 2019, In: Nucleic Acids Research. 47, 6, p. 3208-3222 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2017

  A widespread family of serine/threonine protein phosphatases shares a common regulatory switch with proteasomal proteases

  Bradshaw, N., Levdikov, V. M., Zimanyi, C. M., Gaudet, R., Wilkinson, A. J. & Losick, R., 12 Jun 2017, In: eLife. 6, e26111.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2016

  Human Lin28 forms a high-affinity 1:1 complex with the 106~363 cluster miRNA miR-363

  Peters, D. T., Fung, H. K., Levdikov, V. M., Irmscher, T., Warrander, F. C., Greive, S. J., Kovalevskiy, O., Isaacs, H. V., Coles, M. C. & Antson, A. A., 25 Aug 2016, In: Biochemistry. 55, p. 5021−5027 7 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

• Structure of the Branched Chain Amino Acid and GTP Sensing Global Regulator, CodY, from Bacillus subtilis

  Levdikov, V. M., Blagova, E. V., Young, V. L., Belitsky, B. R., Lebedev, A., Sonenshein, A. L. & Wilkinson, A. J., 23 Dec 2016, (E-pub ahead of print) In: The Journal of biological chemistry. p. 1-36 36 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

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• 2013

  12-Fold symmetry of the putative portal protein from the Thermus thermophilus bacteriophage G20C determined by X-ray analysis

  Williams, L. S., Levdikov, V. M., Minakhin, L., Severinov, K. & Antson, A. A., Nov 2013, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 69, 11, p. 1239-1241 3 p.

  Research output: Contribution to journal › Article › peer-review

• The putative small terminase from the thermophilic dsDNA bacteriophage G20C is a nine-subunit oligomer

  Loredo-Varela, J., Chechik, M., Levdikov, V. M., Abd-El-Aziz, A., Minakhin, L., Severinov, K., Smits, C. & Antson, A. A., Aug 2013, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 69, 8, p. 876-879 4 p.

  Research output: Contribution to journal › Article › peer-review
• 2012

  Structure of components of an intercellular channel complex in sporulating Bacillus subtilis

  Levdikov, V., Blagova, L., McFeat, A. J., Fogg, M. J., Wilson, K. S. & Wilkinson, A., 3 Apr 2012, In: Proceedings of the National Academy of Sciences of the United States of America. 109, 14, p. 5441-5445 5 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the Phosphatase Domain of the Cell Fate Determinant SpoIIE from Bacillus subtilis

  Levdikov, V. M., Blagova, E. V., Rawlings, A. E., Jameson, K., Tunaley, J., Hart, D. J., Barak, I. & Wilkinson, A. J., 13 Jan 2012, In: Journal of Molecular Biology. 415, 2, p. 343-358 16 p.

  Research output: Contribution to journal › Article › peer-review
• 2011

  Compensating Stereochemical Changes Allow Murein Tripeptide to Be Accommodated in a Conventional Peptide-binding Protein

  Maqbool, A., Levdikov, V. M., Blagova, E. V., Herve, M., Horler, R. S. P., Wilkinson, A. J. & Thomas, G. H., 9 Sept 2011, In: Journal of Biological Chemistry. 286, 36, p. 31512-31521 10 p.

  Research output: Contribution to journal › Article › peer-review

• Structure and Organisation of SinR, the Master Regulator of Biofilm Formation in Bacillus subtilis

  Colledge, V. L., Fogg, M. J., Levdikov, V. M., Leech, A., Dodson, E. J. & Wilkinson, A. J., 19 Aug 2011, In: Journal of Molecular Biology. 411, 3, p. 597-613 17 p.

  Research output: Contribution to journal › Article › peer-review

• The Structure and Interactions of SpoIISA and SpoIISB, a Toxin-Antitoxin System in Bacillus subtilis

  Florek, P., Levdikov, V. M., Blagova, E., Lebedev, A. A., Skrabana, R., Resetarova, S., Pavelcikova, P., Barak, I. & Wilkinson, A. J., 25 Feb 2011, In: Journal of Biological Chemistry. 286, 8, p. 6808-6819 12 p.

  Research output: Contribution to journal › Article › peer-review
• 2010

  Expression of soluble, active fragments of the morphogenetic protein SpoIIE from Bacillus subtilis using a library-based construct screen

  Rawlings, A. E., Levdikov, V. M., Blagova, E., Colledge, V. L., Mas, P. J., Tunaley, J., Vavrova, L., Wilson, K. S., Barak, I., Hart, D. J. & Wilkinson, A. J., Nov 2010, In: PROTEIN ENGINEERING DESIGN. 23, 11, p. 817-825 9 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of the catalytic domain of the human mitochondrial Lon protease: Proposed relation of oligomer formation and activity

  Garcia-Nafria, J., Ondrovicova, G., Blagova, E., Levdikov, V. M., Bauer, J. A., Suzuki, C. K., Kutejova, E., Wilkinson, A. J. & Wilson, K. S., May 2010, In: Protein Science. 19, 5, p. 987-999 13 p.

  Research output: Contribution to journal › Article › peer-review
• 2009

  Genetic and Biochemical Analysis of the Interaction of Bacillus subtilis CodY with Branched-Chain Amino Acids

  Villapakkam, A. C., Handke, L. D., Belitsky, B. R., Levdikov, V. M., Wilkinson, A. J. & Sonenshein, A. L., 15 Nov 2009, In: Journal of Bacteriology. 191, 22, p. 6865-6876 12 p.

  Research output: Contribution to journal › Article › peer-review

• Structural Rearrangement Accompanying Ligand Binding in the GAF Domain of CodY from Bacillus subtilis

  Levdikov, V. M., Blagova, E., Colledge, V. L., Lebedev, A. A., Williamson, D. C., Sonenshein, A. L. & Wilkinson, A. J., 31 Jul 2009, In: Journal of Molecular Biology. 390, 5, p. 1007-1018 12 p.

  Research output: Contribution to journal › Article › peer-review

• The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 angstrom resolution

  Rawlings, A. E., Blagova, E. V., Levdikov, V. M., Fogg, M. J., Wilson, K. S. & Wilkinson, A. J., Jan 2009, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 65, Part 1, p. 2-7 5 p.

  Research output: Contribution to journal › Article › peer-review

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• 2008

  Functional role for a conserved aspartate in the Spo0E signature motif involved in the dephosphorylation of the Bacillus subtilis sporulation regulator Spo0A

  Diaz, A. R., Stephenson, S., Green, J. M., Levdikov, V. M., Wilkinson, A. J. & Perego, M., 1 Feb 2008, In: Journal of Biological Chemistry. 283, 5, p. 2962-2972 11 p.

  Research output: Contribution to journal › Article › peer-review
• 2006

  Application of high-throughput technologies to a structural proteomics-type analysis of Bacillus anthracis

  Au, K., Berrow, N. S., Blagova, E., Boucher, I. W., Boyle, M. P., Brannigan, J. A., Carter, L. G., Dierks, T., Folkers, G., Grenha, R., Harlos, K., Kaptein, R., Kalliomaa, A. K., Levdikov, V. M., Meier, C., Milioti, N., Moroz, O., Muller, A., Owens, R. J. & Rzechorzek, N. & 9 others, Sainsbury, S., Stuart, D. I., Walter, T. S., Waterman, D. G., Wilkinson, A. J., Wilson, K. S., Zaccai, N., Esnouf, R. M. & Fogg, M. J., Oct 2006, In: Acta Crystallographica. Section D, Biological Crystallography. 62, p. 1267-1275 9 p.

  Research output: Contribution to journal › Article › peer-review

• Crystal structure of dihydrodipicolinate synthase (BA3935) from Bacillus anthracis at 1.94 angstrom resolution

  Blagova, E., Levdikov, V., Milioti, N., Fogg, M. J., Kalliomaa, A. K., Brannigan, J. A., Wilson, K. S. & Wilkinson, A. J., 1 Jan 2006, In: Proteins - Structure Function and Genetics. 62, 1, p. 297-301 5 p.

  Research output: Contribution to journal › Article › peer-review

• SPINE workshop on automated X-ray analysis: a progress report

  Bahar, M., Ballard, C., Cohen, S. X., Cowtan, K. D., Dodson, E. J., Emsley, P., Esnouf, R. M., Keegan, R., Lamzin, V., Langer, G., Levdikov, V., Long, F., Meier, C., Muller, A., Murshudov, G. N., Perrakis, A., Siebold, C., Stein, N., Turkenburg, M. G. W. & Vagin, A. A. & 3 others, Winn, M., Winter, G. & Wilson, K. S., Oct 2006, In: Acta Crystallographica. Section D, Biological Crystallography. 62, p. 1170-1183 14 p.

  Research output: Contribution to journal › Article › peer-review

• The GTPase, CpgA(YloQ), a putative translation factor, is implicated in morphogenesis in Bacillus subtilis

  Cladiere, L., Hamze, K., Madec, E., Levdikov, V. M., Wilkinson, A. J., Holland, I. B. & Seror, S. J., Apr 2006, In: MOLECULAR GENETICS AND GENOMICS. 275, 4, p. 409-420 12 p.

  Research output: Contribution to journal › Article › peer-review

• The structure of CodY, a GTP- and isoleucine-responsive regulator of stationary phase and virulence in Gram-positive bacteria

  Levdikov, V. M., Blagova, E., Joseph, P., Sonenshein, A. L. & Wilkinson, T., 21 Apr 2006, In: Journal of Biological Chemistry. 281, 16, p. 11366-11373 8 p.

  Research output: Contribution to journal › Article › peer-review
• 2005

  An ATP-binding cassette-type cysteine transporter in Campylobacter jejuni inferred from the structure of an extracytoplasmic solute receptor protein

  Muller, A., Thomas, G. H., Horler, R., Brannigan, J. A., Blagova, E., Levdikov, V., Fogg, M. J., Wilson, K. S. & Wilkinson, A. J., Jul 2005, In: Molecular Microbiology. 57, 1, p. 143-155 13 p.

  Research output: Contribution to journal › Article › peer-review

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• Crystallographic studies of the GTP-dependent transcriptional regulator CodY from Bacillus subtilis.

  Blagova, E. V., Levdikov, V. M., Wilson, K. S., Sonenshein, A. L. & Wilkinson, A. J., Jul 2005, In: FEBS Journal. 272, p. 179-180 2 p.

  Research output: Contribution to journal › Article › peer-review

• Crystal structure of PurE (BA0288) from Bacillus anthracis at 1.8 angstrom resolution

  Boyle, M. P., Kalliomaa, A. K., Levdikov, V., Blagova, E., Fogg, M. J., Brannigan, J. A., Wilson, K. S. & Wilkinson, A. J., 15 Nov 2005, In: Proteins - Structure Function and Genetics. 61, 3, p. 674-676 3 p.

  Research output: Contribution to journal › Article › peer-review

• SPINE in York

  Levdikov, V. M., Blagova, E. V., Brannigan, J. A., Fogg, M. J., Moroz, O. V., Boyle, M., Grenha, R., Muller, A., Wade, J., Wilkinson, A. J. & Wilson, K. S., Jul 2005, In: FEBS Journal. 272, p. 513-513 1 p.

  Research output: Contribution to journal › Article › peer-review

• Structure of purine nucleoside phosphorylase (DeoD) from Bacillus anthracis

  Grenha, R., Levdikov, V. M., Fogg, M. J., Blagova, E. V., Brannigan, J. A., Wilkinson, A. J. & Wilson, K. S., May 2005, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 61, 5, p. 459-462 4 p.

  Research output: Contribution to journal › Article › peer-review

  File

• Structures of two superoxide dismutases from Bacillus anthracis reveal a novel active centre

  Boucher, I. W., Kalliomaa, A. K., Levdikov, V. M., Blagova, E. V., Fogg, M. J., Brannigan, J. A., Wilson, K. S. & Wilkinson, A. J., Jul 2005, In: Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 61, p. 621-624 4 p.

  Research output: Contribution to journal › Article › peer-review

• The structure of the oligopeptide-binding protein, AppA, from Bacillus subtilis in complex with a nonapeptide

  Levdikov, V. M., Blagova, E. V., Brannigan, J. A., Wright, L., Vagin, A. A. & Wilkinson, A. J., 28 Jan 2005, In: Journal of Molecular Biology. 345, 4, p. 879-892 14 p.

  Research output: Contribution to journal › Article › peer-review
• 2004

  Crystallization of the oligopeptide-binding protein AppA from Bacillus subtilis

  Wright, L., Blagova, E., Levdikov, V. M., Brannigan, J. A., Pattenden, R. J., Chambers, J. & Wilkinson, A. J., Jan 2004, In: Acta Crystallographica. Section D, Biological Crystallography. 60, 1, p. 175-177 3 p.

  Research output: Contribution to journal › Article › peer-review

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• Crystallization of YIoQ, a GTPase of unknown function essential for Bacillus subtilis viability

  Cladiere, L., Blagova, E., Levdikov, V. M., Brannigan, J. A., Seror, S. J. & Wilkinson, A. J., Feb 2004, In: Acta Crystallographica. Section D, Biological Crystallography. 60, 2, p. 329-330 2 p.

  Research output: Contribution to journal › Article › peer-review

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• The crystal structure of YloQ, a circularly permuted GTPase essential for Bacillus subtilis viability

  Levdikov, V. M., Blagova, E. V., Brannigan, J. A., Cladiere, L., Antson, A. A., Isupov, M. N., Seror, S. J. & Wilkinson, A. J., 16 Jul 2004, In: Journal of Molecular Biology. 340, 4, p. 767-782 16 p.

  Research output: Contribution to journal › Article › peer-review
• 2003

  Crystallization of the GTP-dependent transcriptional regulator CodY from Bacillus subtilis

  Blagova, E. V., Levdikov, V. M., Tachikawa, K., Sonenshein, A. L. & Wilkinson, A. J., Jan 2003, In: Acta Crystallographica. Section D, Biological Crystallography. 59, p. 155-157 3 p.

  Research output: Contribution to journal › Article › peer-review
• 1998

  The structure of SAICAR synthase: an enzyme in the de novo pathway of purine nucleotide biosynthesis

  Levdikov, V. M., Barynin, V. V., Grebenko, A. I., Melik-Adamyan, W. R., Lamzin, V. S. & Wilson, K. S., 15 Mar 1998, In: Structure. 6, 3, p. 363-376 14 p.

  Research output: Contribution to journal › Article › peer-review

• 1997

  Three-dimensional structure of Serratia marcescens nuclease at 1.7 Å resolution and mechanism of its action

  Lunin, V. Y., Levdikov, V. M., Shlyapnikov, S. V., Blagova, E. V., Lunin, V. V., Wilson, K. S. & Mikhailov, A. M., 21 Jul 1997, In: FEBS Letters. 412, 1, p. 217-222 6 p.

  Research output: Contribution to journal › Article › peer-review