William Paul Unsworth

Dr

Senior Lecturer, Chemistry

Former affiliations

Postdoc Research Fellow, Chemistry
Postdoctoral Research Fellow, Chemistry
Research and Teaching Fellow, Chemistry
Postdoc Research Associate, Chemistry
Leverhulme Fellow, Chemistry
Eleanor Dodson Fellow, Chemistry
Senior Research Fellow, Chemistry

https://orcid.org/0000-0002-9169-5156

Phone(01904) 322533
Emailwilliam.unsworthyork.acuk

Accepting PhD Students

83 Article
7 Review article
3 Chapter
2 Comment/debate

A Modular Strategy for the Synthesis of Macrocycles and Medium-Sized Rings via Cyclization/Ring Expansion Cascade Reactions
Zalessky, I., Wootton, J. M., Tam, J. K. F., Spurling, D. E., Glover-Humphreys, W. C., Donald, J. R., Orukotan, W. E., Duff, L. C., Knapper, B. J., Whitwood, A. C., Tanner, T. F. N., Miah, A. H., Lynam, J. M. & Unsworth, W. P., 19 Feb 2024, (E-pub ahead of print) In: Journal of the American Chemical Society. 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Asymmetric ‘Clip-Cycle’ synthesis of 3-spiropiperidines
Ravi, S. R., Fairlamb, I. J. S., Unsworth, W. P. & Clarke, P. A., 20 Nov 2024, (E-pub ahead of print) In: Organic and Biomolecular Chemistry. 4 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Cascade ring expansion reactions for the synthesis of medium-sized rings and macrocycles
Wootton, J. M., Tam, J. K. F. & Unsworth, W. P., 18 Apr 2024, (E-pub ahead of print) In: Chemical communications. 11 p.
Research output: Contribution to journal › Review article › peer-review

Open Access
File

2 Not started
4 Active
10 Finished

MC4DD: Macrocycles for Drug Discovery
Unsworth, W. P. (Principal investigator)
EUROPEAN COMMISSION
1/11/24 → 31/10/28
Project: Research project (funded) › Research
Discovery and reconstitution of securinine alkaloid biosynthesis
Lichman, B. R. (Principal investigator), Grogan, G. J. (Co-investigator), O'Toole, P. J. (Co-investigator) & Unsworth, W. P. (Co-investigator)
BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL)
3/06/24 → 2/06/27
Project: Research project (funded) › Research
Multifunctional Peroxygenase Catalysis for Synthetic Chemistry
Grogan, G. J. (Principal investigator) & Unsworth, W. P. (Co-investigator)
EPSRC
21/08/23 → 20/08/26
Project: Research project (funded) › Research

Invited talk at University of Birmingham (online)
Unsworth, W. P. (Invited speaker)
25 Jan 2021
Activity: Talk or presentation › Invited talk
Swiss Chemical Society Fall Meeting (Online)
Unsworth, W. P. (Keynote/plenary speaker)
25 Aug 2020
Activity: Participating in or organising an event › Conference participation
Invited talk at 'Preparing for Fellowship Success Retreat'
Unsworth, W. P. (Invited speaker)
4 Mar 2020
Activity: Talk or presentation › Invited talk

Divergent Reactivity of Indole-Tethered Ynones with Silver(I) and Gold(I) Catalysts: A Combined Synthetic and Computational Study
Unsworth, W. P. (Creator), University of York, 17 Jul 2018
DOI: 10.15124/b72b66ce-1d5c-4e9e-8c80-a4b1c00380a8
Dataset
Raw data for the paper 'Dearomatisation approaches to spirocyclic dienones via the electrophilic activation of alkynes'
Unsworth, W. P. (Creator), Clarke, A. K. (Contributor), Liddon, J. T. R. (Contributor), Taylor, R. J. K. (Contributor) & Cuthbertson, J. D. (Contributor), University of York, 3 May 2017
DOI: 10.15124/59cdbcad-ab0e-46e0-8c13-5be98b3f9867
Dataset
Raw data for the paper 'Synthetic approaches to pallimamine and analogues using direct imine acylation'
Unsworth, W. P. (Creator), Taylor, R. J. K. (Contributor), Ronson, T. O. (Contributor) & Kitsiou, C. (Contributor), University of York, 3 May 2017
DOI: 10.15124/ade57976-50c9-4146-bb44-c65b5d2ca5f1
Dataset

AmigoChem collaboration prize
Unsworth, W. P. (Recipient), Sept 2017
Prize: Prize (including medals and awards)
European Lead Factory Library design award
Unsworth, W. P. (Recipient), Oct 2017
Prize: Prize (including medals and awards)
RSC Hickinbottam award
Unsworth, W. P. (Recipient), 2018
Prize: Prize (including medals and awards)