Application of activity-based glycosidase probes for mechanism, enzyme discovery and clinical diagnosis

Davies, Gideon John (Principal investigator)

Chemistry

Project: Research project (funded) › Research

Status	Finished
Effective start/end date	1/01/18 → 31/12/21

Funding

BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL): £728,794.00

25 Article

Molecular basis for inhibition of heparanases and β-glucuronidases by siastatin B
Chen, Y., van den Nieuwendijk, A. M. C. H., Wu, L., Moran, E., Skoulikopoulou, F., Riet, V. V., Overkleeft, H. S., Davies, G. J. & Armstrong, Z., 2024, In: Journal of the American Chemical Society. 146, 1, p. 125–133 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Parascedosporium putredinis NO1 tailors its secretome for different lignocellulosic substrates
Scott, C., McGregor, N., Leadbeater, D., Oates, N., Hoßbach, J., Abood, A., Setchfield, A., Dowle, A., Overkleeft, H., Davies, G. J. & Bruce, N., 1 Jul 2024, In: Microbiology spectrum. 12, 7, 23 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4-O-Substituted Glucuronic Cyclophellitols are Selective Mechanism-Based Heparanase Inhibitors
Borlandelli, V., Armstrong, Z., Nin-Hill, A., Codée, J. D. C., Raich, L., Artola, M., Rovira, C., Davies, G. J. & Overkleeft, H. S., 14 Feb 2023, In: ChemMedChem. 18, 4, 7 p., e202200580.
Research output: Contribution to journal › Article › peer-review

Open Access
File