Application of genomics to Leishmaniasis patient treatment in Brazil

Project: Research project (funded)Internal pump-priming

Project Details

Description

Leishmaniasis is a globally distributed disease associated with poverty that affects up to 1 million people each year. It is caused by Leishmania parasites and transmitted by sand flies. Severe forms of leishmaniasis are can be fatal if untreated. This project will sequence multiple genomes of Leishmania strains from of Leishmania strains from Brazil, South and Central America. This genome data will help us identify biomarkers that are predictive of severe disease, identify vaccine candidates and allow us to detect new drug-resistant strains. In addition, we will develop rapid on-site DNA sequencing methods may lead to personalised disease treatments (impact; personalised medicine and infectious disease management).

Layman's description

Leishmaniasis is a globally distributed disease associated with poverty that affects up to 1 million people each year. It is caused by Leishmania parasites and transmitted by sand flies. Severe forms of leishmaniasis are can be fatal if untreated. This project will sequence multiple genomes of Leishmania strains from of Leishmania strains from Brazil, South and Central America. This genome data will help us identify biomarkers that are predictive of severe disease, identify vaccine candidates and allow us to detect new drug-resistant strains. In addition, we will develop rapid on-site DNA sequencing methods may lead to personalised disease treatments (impact; personalised medicine and infectious disease management).
StatusFinished
Effective start/end date1/12/1831/03/19