Activities per year
Project Details
Description
Parkinson’s Disease is the major neurodegenerative disease affecting the UK population after Alzheimer’s disease. It manifests as a movement disorder due to the loss of dopaminergic neurons in the part of the brain that controls movement, but then spreads to other regions of brain leading to dementia and early death. There are therapeutic interventions known to slow disease progression but as yet no identified cure. It is known that high levels of oxidative stress in the brain leads to neuronal death. This project aims to demonstrate experimentally how certain deficits at a genetic level lead to malfunctioning of the molecular mechanisms and pathways involved in eliminating harmful reactive oxygen species from the brain. An improved understanding of these processes opens up the possibility of developing new therapies against Parkinson's Disease.
Status | Finished |
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Effective start/end date | 1/01/17 → 31/03/17 |
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York Festival of Ideas
Sean Sweeney (Chair)
11 Jun 2019Activity: Participating in or organising an event › Festival
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Redox Signalling in Physiology, Ageing and Disease
Sean Sweeney (Speaker)
1 Jun 2019 → 3 Jun 2019Activity: Talk or presentation › Oral presentation
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Biochemical Society Meeting: Reactive Oxygen Species and mitochondria in nervous system function and Disease
Sean Sweeney (Organiser)
27 Mar 2017 → 29 Mar 2017Activity: Participating in or organising an event › Conference