CFH2a Priming - Microelectronic integrated circuit biosensors for susceptibility testing

Project: Other internal award

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Drug resistant infections (DRI) have been identified as a major threat to public health worldwide. A key factor driving the increasing prevalence of DRI is the inappropriate use of antibiotics, both due to over prescription and incorrect choice of antimicrobial therapy. Ultimately, rational and targeted prescribing of antibiotics requires evidence-based diagnostics that can rapidly and accurately test antimicrobial susceptibility. The technology should be low cost and ideally portable for use by non-experts at point of care. This project will develop a bespoke silicon microchip that is capable of rapidly identifying resistance to β-lactam antibiotics. While we focus here on DRI, the electronic biosensor technology is generic and can be applied to a range of diagnostic challenges across healthcare.
Effective start/end date1/06/1830/06/19

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