Dissection and targeting of glycosidases in human health: identification & dissection of the protein complexes of the O-GlcNAc modification

Project: Research project (funded) › Research

Status	Finished
Effective start/end date	1/10/17 → 31/03/21

Potent De Novo Macrocyclic Peptides That Inhibit O-GlcNAc Transferase through an Allosteric Mechanism
Alteen, M. G., Peacock, H., Meek, R. W., Busmann, J. A., Zhu, S., Davies, G. J., Suga, H. & Vocadlo, D. J., 26 Jan 2023, In: Angewandte Chemie - International Edition. 62, 5, 9 p., e202215671.
Research output: Contribution to journal › Article › peer-review

Open Access
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Cryo-EM structures of human fucosidase FucA1 reveal insight into substate recognition and catalysis
Armstrong, Z., Meek, R. W., Wu, L., Blaza, J. N. & Davies, G. J., 29 Jul 2022, (E-pub ahead of print) In: Structure. 30, 15 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Cryo-EM structure provides insights into the dimer arrangement of the O-linked β-N-acetylglucosamine transferase OGT
Meek, R. W., Blaza, J. N., Busmann, J. A., Alteen, M. G., Vocadlo, D. J. & Davies, G. J., 11 Nov 2021, In: Nature Communications. 12, 1, 10 p., 6508.
Research output: Contribution to journal › Article › peer-review

Open Access
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Project Details