Fragment-based activation and modification of industrial enzymes

Hubbard, Roderick Eliot (Principal investigator)
Darby, John Fintan (Co-investigator)
Davies, Gideon John (Co-investigator)
O'Brien, Peter Andrew (Co-investigator)

Chemistry

Project: Research project (funded) › Research

Status	Finished
Effective start/end date	29/04/16 → 28/08/19

Funding

BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL): £708,092.00

5 Article
1 Chapter

¹H, ¹³C, ¹⁵N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei
Makraki, E., Carneiro, M. G., Heyam, A., Eiso, A. B., Siegal, G. & Hubbard, R. E., 19 Jun 2020, (E-pub ahead of print) In: Biomolecular NMR assignments. 4 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Design and Synthesis of 56 Shape Diverse 3-D Fragments
O'Brien, P., Downes, T. D., Jones, S. P., Klein, H. F., Wheldon, M. C., Atobe, M., Bond, P. S., Firth, J. D., Chan, N. S., Waddelove, L., Hubbard, R. E., Blakemore, D. C., De Fusco, C., Roughley, S. D., Vidler, L. R., Whatton, M. A., Woolford, A.J.-A. & Wrigley, G. L., 21 Apr 2020, (E-pub ahead of print) In: Chemistry : A European Journal. 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Fragment-derived modulators of an industrial β-glucosidase
Makraki, E., Darby, J. F., Carneiro, M. G., Firth, J. D., Heyam, A., Ab, E., O'Brien, P., Siegal, G. & Hubbard, R. E., 26 Nov 2020, In: The Biochemical journal. 477, 22, p. 4383-4395 13 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

Data underpinning Design and Synthesis of 56 Shape Diverse 3‐D Fragments
O'Brien, P. A. (Creator), Firth, J. (Contributor) & Klein, H. (Contributor), University of York, 2020
DOI: 10.15124/56e2e1ac-32ae-4753-8ef1-320d41b0c4d7
Dataset