Fragments Training Network (H2020-MSCA-ITN-2015)

Search results

• 2023

  Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors

  FitzGerald, E. A., Vagrys, D., Opassi, G., Klein, H. F., Hamilton, D. J., Talibov, V. O., Abramsson, M., Moberg, A., Lindgren, M. T., Holmgren, C., Davis, B., O'Brien, P., Wijtmans, M., Hubbard, R. E., de Esch, I. J. P. & Danielson, U. H., 14 Sept 2023, In: SLAS Discovery. 12 p.

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• 2020

  ¹H, ¹³C, ¹⁵N backbone and IVL methyl group resonance assignment of the fungal β-glucosidase from Trichoderma reesei

  Makraki, E., Carneiro, M. G., Heyam, A., Eiso, A. B., Siegal, G. & Hubbard, R. E., 19 Jun 2020, (E-pub ahead of print) In: Biomolecular NMR assignments. 4 p.

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• Design and Synthesis of 56 Shape Diverse 3-D Fragments

  O'Brien, P., Downes, T. D., Jones, S. P., Klein, H. F., Wheldon, M. C., Atobe, M., Bond, P. S., Firth, J. D., Chan, N. S., Waddelove, L., Hubbard, R. E., Blakemore, D. C., De Fusco, C., Roughley, S. D., Vidler, L. R., Whatton, M. A., Woolford, A.J.-A. & Wrigley, G. L., 21 Apr 2020, (E-pub ahead of print) In: Chemistry : A European Journal. 9 p.

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• Exploring idp–ligand interactions: Tau k18 as a test case

  Vagrys, D., Davidson, J., Chen, I., Hubbard, R. E. & Davis, B., 24 Jul 2020, In: International Journal of Molecular Sciences. 21, 15, 15 p., 5257.

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• Fragment-derived modulators of an industrial β-glucosidase

  Makraki, E., Darby, J. F., Carneiro, M. G., Firth, J. D., Heyam, A., Ab, E., O'Brien, P., Siegal, G. & Hubbard, R. E., 26 Nov 2020, In: The Biochemical journal. 477, 22, p. 4383-4395 13 p.

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• 2018

  Using fragment-based approaches to discover new antibiotics

  Hubbard, R. E. & Lamoree, B., 1 Jul 2018, In: SLAS Discovery. 23, 6, p. 495-510

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• When fragments link: a bibliometric perspective on the development of fragment-based drug discovery

  Romasanta, A. K. S., van der Sijde, P., Hellsten, I., Hubbard, R. E., Keseru, G. M., van Muijlwijk-Koezen, J. & de Esch, I. J. P., 5 May 2018, (E-pub ahead of print) In: Drug discovery today. 14 p.

  Research output: Contribution to journal › Article › peer-review

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