N-Myristol Transferase as a drug target for anti-malarial therapy

Project: Research project (funded) › Research

Status	Finished
Effective start/end date	1/06/10 → 31/05/14

Diverse modes of binding in structures of Leishmania major N-myristoyltransferase with selective inhibitors
Brannigan, J. A., Roberts, S. M., Bell, A. S., Hutton, J. A., Hodgkinson, M. R., Tate, E. W., Leatherbarrow, R. J., Smith, D. F. & Wilkinson, A. J., Jul 2014, In: IUCrJ. 1, 4, p. 250-260 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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Discovery of Novel and Ligand-Efficient Inhibitors of Plasmodium falciparum and Plasmodium vivax N-Myristoyltransferase
Rackham, M. D., Brannigan, J. A., Moss, D. K., Yu, Z., Wilkinson, A. J., Holder, A. A., Tate, E. W. & Leatherbarrow, R. J., 10 Jan 2013, In: JOURNAL OF MEDICINAL CHEMISTRY. 56, 1, p. 371-375 5 p.
Research output: Contribution to journal › Article › peer-review
A fluorescence-based assay for N-myristoyltransferase activity
Goncalves, V., Brannigan, J. A., Thinon, E., Olaleye, T. O., Serwa, R., Lanzarone, S., Wilkinson, A. J., Tate, E. W. & Leatherbarrow, R. J., 1 Feb 2012, In: ANALYTICAL BIOCHEMISTRY. 421, 1, p. 342-344 3 p.
Research output: Contribution to journal › Article › peer-review

Project Details