Safe Genes Daisy Drives

Alphey, Luke Stephen (Principal investigator)
Anderson, Michelle (Researcher)
Ang Xin De, Joshua (Researcher)

Biology

Project: Other project › Project from former institution

Description

We aimed to develop a daisy chain gene drive in Aedes aegypti and Culex quinquefasciatus mosquitoes.

Status	Finished
Effective start/end date	1/09/17 → 31/08/19

6 Article

A multiplexed, confinable CRISPR/Cas9 gene drive propagates in caged Aedes aegypti populations
Anderson, M., Gonzalez Fernandez, E., Edgington, M. P., Ang Xin De, J., Purusothaman, D.-K., Shackleford, L., Nevard, K., Verkuijl, S., Harvey-Samuel, T., Leftwich, P., Esvelt, K. & Alphey, L. S., 25 Jan 2024, In: Nature Communications. 15, 13 p., 729.
Research output: Contribution to journal › Article › peer-review

Open Access
File
A synthetic biology approach to transgene expression in insects
Leftwich, P., Purcell, J., Anderson, M., Fragkoudis, R., Basu, S., Lycett, G. & Alphey, L. S., 28 Aug 2024, (E-pub ahead of print) In: ACS Synthetic Biology. 5 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
AePUb promoter length modulates gene expression in Aedes aegypti
Anderson, M., Leftwich, P., Wilson, R., Carabajal Paladino, L. Z., Adelman, Z. & Alphey, L. S., 21 Nov 2023, In: Scientific Reports. 13, 7 p., 20352.
Research output: Contribution to journal › Article › peer-review

Open Access
File

Code - Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements
Verkuijl, S. (Creator), Anderson, M. (Supervisor) & Edgington, M. P. (Creator), University of York, 18 Jan 2023
DOI: 10.15124/15640775-cffd-40e3-9055-890870d15db9
Dataset