Structural and fragment approaches to the modulation of O-GlcNAc in cells

Davies, Gideon John (Principal investigator)
Hubbard, Roderick Eliot (Co-investigator)

Chemistry

Project: Research project (funded) › Research

Status	Finished
Effective start/end date	29/04/13 → 31/10/16

Funding

BBSRC (BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL): £730,226.00

3 Article

Structural and functional insight into human O-GlcNAcase
Roth, C., Chan, O. Y., Offen, W. A., Hemsworth, G. R., Willems, L. I., King, D. T., Varghese, V., Britton, R., Vocadlo, D. J. & Davies, G. J., 1 Jun 2017, In: NATURE CHEMICAL BIOLOGY. 13, 6, p. 610-612 3 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Discovery of selective small-molecule activators of a bacterial glycoside hydrolase
Darby, J. F., Landström, J., Roth, C., He, Y., Davies, G. J. & Hubbard, R. E., 1 Dec 2014, In: Angewandte Chemie International Edition. 53, 49, p. 13419-13423
Research output: Contribution to journal › Article › peer-review
Three-dimensional structure of a Streptomyces sviceus GNAT acetyltransferase with similarity to the C-terminal domain of the human GH84 O-GlcNAcase
He, Y., Roth, C., Turkenburg, J. P. & Davies, G. J., 1 Jan 2014, In: Acta Crystallographica. Section D, Biological Crystallography. 70, 1, p. 186-195 10 p.
Research output: Contribution to journal › Article › peer-review