2-CHLOROMETHYL-4-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE - AN ENZYME-ACTIVATED IRREVERSIBLE INHIBITOR OF YEAST ALPHA-GLUCOSIDASE

J C  BRIGGS; A H  HAINES; R J K  TAYLOR

2-CHLOROMETHYL-4-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE - AN ENZYME-ACTIVATED IRREVERSIBLE INHIBITOR OF YEAST ALPHA-GLUCOSIDASE

J C BRIGGS, A H HAINES, R J K TAYLOR

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

2-Chloromethyl-4-nitrophenyl alpha-D-glucopyranoside, prepared by a novel, four-step route from 2-methylphenyl alpha-D-glucopyranoside tetraacetate, is highly effective as an enzyme-activated irreversible inhibitor of yeast alpha-glucosidase and is much superior in this respect to 2-chloromethylphenyl alpha-D-glucopyranoside.

Original language	English
Pages (from-to)	1039-1041
Number of pages	3
Journal	JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
Issue number	15
Publication status	Published - 1 Aug 1992

Keywords

BETA-GLUCOSIDASE
POTENT

Cite this

@article{ef327ca3324d46229c38891c4c12390a,

title = "2-CHLOROMETHYL-4-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE - AN ENZYME-ACTIVATED IRREVERSIBLE INHIBITOR OF YEAST ALPHA-GLUCOSIDASE",

abstract = "2-Chloromethyl-4-nitrophenyl alpha-D-glucopyranoside, prepared by a novel, four-step route from 2-methylphenyl alpha-D-glucopyranoside tetraacetate, is highly effective as an enzyme-activated irreversible inhibitor of yeast alpha-glucosidase and is much superior in this respect to 2-chloromethylphenyl alpha-D-glucopyranoside.",

keywords = "BETA-GLUCOSIDASE, POTENT",

author = "BRIGGS, {J C} and HAINES, {A H} and TAYLOR, {R J K}",

year = "1992",

month = aug,

day = "1",

language = "English",

pages = "1039--1041",

journal = "JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS",

issn = "0022-4936",

publisher = "Chemical Society",

number = "15",

}

TY - JOUR

T1 - 2-CHLOROMETHYL-4-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE - AN ENZYME-ACTIVATED IRREVERSIBLE INHIBITOR OF YEAST ALPHA-GLUCOSIDASE

AU - BRIGGS, J C

AU - HAINES, A H

AU - TAYLOR, R J K

PY - 1992/8/1

Y1 - 1992/8/1

N2 - 2-Chloromethyl-4-nitrophenyl alpha-D-glucopyranoside, prepared by a novel, four-step route from 2-methylphenyl alpha-D-glucopyranoside tetraacetate, is highly effective as an enzyme-activated irreversible inhibitor of yeast alpha-glucosidase and is much superior in this respect to 2-chloromethylphenyl alpha-D-glucopyranoside.

AB - 2-Chloromethyl-4-nitrophenyl alpha-D-glucopyranoside, prepared by a novel, four-step route from 2-methylphenyl alpha-D-glucopyranoside tetraacetate, is highly effective as an enzyme-activated irreversible inhibitor of yeast alpha-glucosidase and is much superior in this respect to 2-chloromethylphenyl alpha-D-glucopyranoside.

KW - BETA-GLUCOSIDASE

KW - POTENT

M3 - Article

SN - 0022-4936

SP - 1039

EP - 1041

JO - JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS

JF - JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS

IS - 15

ER -