2-CHLOROMETHYL-4-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE - AN ENZYME-ACTIVATED IRREVERSIBLE INHIBITOR OF YEAST ALPHA-GLUCOSIDASE - Research Database, The University of York

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2-CHLOROMETHYL-4-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE - AN ENZYME-ACTIVATED IRREVERSIBLE INHIBITOR OF YEAST ALPHA-GLUCOSIDASE

Research output: Contribution to journal › Article

Author(s)

J C BRIGGS
A H HAINES
R J K TAYLOR

Department/unit(s)

Chemistry

Publication details

Journal	JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
Date	Published - 1 Aug 1992
Issue number	15
Number of pages	3
Pages (from-to)	1039-1041
Original language	English

Abstract

2-Chloromethyl-4-nitrophenyl alpha-D-glucopyranoside, prepared by a novel, four-step route from 2-methylphenyl alpha-D-glucopyranoside tetraacetate, is highly effective as an enzyme-activated irreversible inhibitor of yeast alpha-glucosidase and is much superior in this respect to 2-chloromethylphenyl alpha-D-glucopyranoside.

Research areas

BETA-GLUCOSIDASE, POTENT

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