A comparison of three SPRITE techniques for the quantitative 3D imaging of the Na spin density on a 4T whole-body machine

TY - JOUR

T1 - A comparison of three SPRITE techniques for the quantitative 3D imaging of the Na spin density on a 4T whole-body machine

AU - Romanzetti, S.

AU - Halse, M.

AU - Kaffanke, J.

AU - Zilles, K.

AU - Balcom, B.J.

AU - Shah, N.J.

PY - 2006/3

Y1 - 2006/3

N2 - Sodium density maps acquired with three SPRITE-based methods have been compared in terms of the resulting quantitative information as well as image quality and acquisition times. Consideration of factors relevant for the clinical implementation of SPRITE shows that the Conical-SPRITE variant is preferred because of a 20-fold reduction in acquisition time, slightly improved image quality, and no loss of quantitative information. The acquisition of a 3D data set (32 × 32 × 16; FOV = 256 × 256 × 160 mm) for the quantitative determination of sodium density is demonstrated. In vivo Conical-SPRITE Na images of the brain of a healthy volunteer were acquired in 30 min with a resolution of 7.5 × 7.5 × 7.5 mm and a signal-to-noise ratio of 23 in cerebrospinal fluid and 17 in brain tissue.

AB - Sodium density maps acquired with three SPRITE-based methods have been compared in terms of the resulting quantitative information as well as image quality and acquisition times. Consideration of factors relevant for the clinical implementation of SPRITE shows that the Conical-SPRITE variant is preferred because of a 20-fold reduction in acquisition time, slightly improved image quality, and no loss of quantitative information. The acquisition of a 3D data set (32 × 32 × 16; FOV = 256 × 256 × 160 mm) for the quantitative determination of sodium density is demonstrated. In vivo Conical-SPRITE Na images of the brain of a healthy volunteer were acquired in 30 min with a resolution of 7.5 × 7.5 × 7.5 mm and a signal-to-noise ratio of 23 in cerebrospinal fluid and 17 in brain tissue.

KW - Sodium

KW - Quadrupolar interaction

KW - SPRITE

UR - http://www.scopus.com/inward/record.url?scp=33645843653&partnerID=8YFLogxK

U2 - 10.1016/j.jmr.2005.11.007

DO - 10.1016/j.jmr.2005.11.007

M3 - Article

AN - SCOPUS:33645843653

SN - 1090-7807

VL - 179

SP - 64

EP - 72

JO - Journal of Magnetic Resonance

JF - Journal of Magnetic Resonance

IS - 1

ER -