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From the same journal

A comparison of three SPRITE techniques for the quantitative 3D imaging of the Na spin density on a 4T whole-body machine

Research output: Contribution to journalArticlepeer-review

Published copy (DOI)


  • S. Romanzetti
  • M. Halse
  • J. Kaffanke
  • K. Zilles
  • B.J. Balcom
  • N.J. Shah


Publication details

JournalJournal of Magnetic Resonance
DateE-pub ahead of print - 1 Dec 2005
DatePublished (current) - Mar 2006
Issue number1
Number of pages9
Pages (from-to)64-72
Early online date1/12/05
Original languageEnglish


Sodium density maps acquired with three SPRITE-based methods have been compared in terms of the resulting quantitative information as well as image quality and acquisition times. Consideration of factors relevant for the clinical implementation of SPRITE shows that the Conical-SPRITE variant is preferred because of a 20-fold reduction in acquisition time, slightly improved image quality, and no loss of quantitative information. The acquisition of a 3D data set (32 × 32 × 16; FOV = 256 × 256 × 160 mm) for the quantitative determination of sodium density is demonstrated. In vivo Conical-SPRITE Na images of the brain of a healthy volunteer were acquired in 30 min with a resolution of 7.5 × 7.5 × 7.5 mm and a signal-to-noise ratio of 23 in cerebrospinal fluid and 17 in brain tissue.

    Research areas

  • Sodium, Quadrupolar interaction, SPRITE

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