Abstract
A short synthesis of the novel antibiotic aranorosin is described which employs a novel hypervalent iodine-mediated oxidative hydroxylation of a tyrosinal derivative in the key step. A similar procedure was employed to prepare 6'-epiaranorosin, and hence establish the stereochemistry of the natural compound.
Original language | English |
---|---|
Pages (from-to) | 5519-5522 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 34 |
Issue number | 35 |
Publication status | Published - 27 Aug 1993 |
Keywords
- HYPERVALENT IODINE OXIDATION
- PSEUDOARACHNIOTUS-ROSEUS
- MONOACETALS