A CONCISE SYNTHESIS OF THE NOVEL ANTIBIOTIC ARANOROSIN

A MCKILLOP, L MCLAREN, R J WATSON, R J K TAYLOR, N LEWIS

Research output: Contribution to journalArticlepeer-review

Abstract

A short synthesis of the novel antibiotic aranorosin is described which employs a novel hypervalent iodine-mediated oxidative hydroxylation of a tyrosinal derivative in the key step. A similar procedure was employed to prepare 6'-epiaranorosin, and hence establish the stereochemistry of the natural compound.

Original languageEnglish
Pages (from-to)5519-5522
Number of pages4
JournalTetrahedron Letters
Volume34
Issue number35
Publication statusPublished - 27 Aug 1993

Keywords

  • HYPERVALENT IODINE OXIDATION
  • PSEUDOARACHNIOTUS-ROSEUS
  • MONOACETALS

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