A CONCISE SYNTHESIS OF THE NOVEL ANTIBIOTIC ARANOROSIN

A  MCKILLOP; L  MCLAREN; R J  WATSON; R J K  TAYLOR; N  LEWIS

A CONCISE SYNTHESIS OF THE NOVEL ANTIBIOTIC ARANOROSIN

A MCKILLOP, L MCLAREN, R J WATSON, R J K TAYLOR, N LEWIS

Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

A short synthesis of the novel antibiotic aranorosin is described which employs a novel hypervalent iodine-mediated oxidative hydroxylation of a tyrosinal derivative in the key step. A similar procedure was employed to prepare 6'-epiaranorosin, and hence establish the stereochemistry of the natural compound.

Original language	English
Pages (from-to)	5519-5522
Number of pages	4
Journal	Tetrahedron Letters
Volume	34
Issue number	35
Publication status	Published - 27 Aug 1993

Keywords

HYPERVALENT IODINE OXIDATION
PSEUDOARACHNIOTUS-ROSEUS
MONOACETALS

Cite this

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title = "A CONCISE SYNTHESIS OF THE NOVEL ANTIBIOTIC ARANOROSIN",

abstract = "A short synthesis of the novel antibiotic aranorosin is described which employs a novel hypervalent iodine-mediated oxidative hydroxylation of a tyrosinal derivative in the key step. A similar procedure was employed to prepare 6'-epiaranorosin, and hence establish the stereochemistry of the natural compound.",

keywords = "HYPERVALENT IODINE OXIDATION, PSEUDOARACHNIOTUS-ROSEUS, MONOACETALS",

author = "A MCKILLOP and L MCLAREN and WATSON, {R J} and TAYLOR, {R J K} and N LEWIS",

year = "1993",

month = aug,

day = "27",

language = "English",

volume = "34",

pages = "5519--5522",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Ltd.",

number = "35",

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TY - JOUR

T1 - A CONCISE SYNTHESIS OF THE NOVEL ANTIBIOTIC ARANOROSIN

AU - MCKILLOP, A

AU - MCLAREN, L

AU - WATSON, R J

AU - TAYLOR, R J K

AU - LEWIS, N

PY - 1993/8/27

Y1 - 1993/8/27

N2 - A short synthesis of the novel antibiotic aranorosin is described which employs a novel hypervalent iodine-mediated oxidative hydroxylation of a tyrosinal derivative in the key step. A similar procedure was employed to prepare 6'-epiaranorosin, and hence establish the stereochemistry of the natural compound.

AB - A short synthesis of the novel antibiotic aranorosin is described which employs a novel hypervalent iodine-mediated oxidative hydroxylation of a tyrosinal derivative in the key step. A similar procedure was employed to prepare 6'-epiaranorosin, and hence establish the stereochemistry of the natural compound.

KW - HYPERVALENT IODINE OXIDATION

KW - PSEUDOARACHNIOTUS-ROSEUS

KW - MONOACETALS

M3 - Article

SN - 0040-4039

VL - 34

SP - 5519

EP - 5522

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 35

ER -