Abstract
The first synthetic route to the tricyclic core of the dictyosphaeric acids has been established starting from readily available (S)-(-)-4-(tert-butyldimethylsilyloxy)cyclohexenone and involving 9 steps, including a ring-closing metathesis to produce a 13-membered macrolactone, and a doubly tethered intramolecular Michael addition.
Original language | English |
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Pages (from-to) | 353-356 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 10 |
Issue number | 2 |
DOIs | |
Publication status | Published - 17 Jan 2008 |
Keywords
- MICHAEL REACTION
- 4-HYDROXYCYCLOHEX-2-ENONE