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From the same journal

A copper(II)-mediated radical cross-dehydrogenative coupling/sulfinic acid elimination approach to 2-quinolones

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Publication details

JournalTetrahedron
DateAccepted/In press - 16 Oct 2019
DateE-pub ahead of print (current) - 21 Oct 2019
Issue number49
Volume75
Early online date21/10/19
Original languageEnglish

Abstract

A new cyclisation procedure to prepare 4-carboxy-quinolin-2-ones via a one-pot Cu(II)-mediated radical cross-dehydrogenative coupling/sulfinic acid elimination of linear anilides is described. Extensions to more complex substrates are also reported as are applications in target synthesis allowing access to natural products isolated from Oryza sativa and HOFQ.

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© 2019 Elsevier Ltd. All rights reserved. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy.

    Research areas

  • 2-Quinolones, Cross-dehydrogenative coupling, Cu(II)-catalysis, Total synthesis

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