A direct C-H/Ar-H coupling approach to oxindoles, thio-oxindoles, 3,4-dihydro-1H-quinolin-2-ones, and 1,2,3,4-tetrahydroquinolines

TY - JOUR

T1 - A direct C-H/Ar-H coupling approach to oxindoles, thio-oxindoles, 3,4-dihydro-1H-quinolin-2-ones, and 1,2,3,4-tetrahydroquinolines

AU - Hurst, Timothy Edgar

AU - Gorman, Ryan Michael

AU - Drouhin, Pauline

AU - Perry, Alexis

AU - Taylor, Richard John Kenneth

N1 - © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

PY - 2014/10/20

Y1 - 2014/10/20

N2 - A copper(II)-catalysed approach to oxindoles, thio-oxindoles, 3,4-dihydro-1H-quinolin-2-ones, and 1,2,3,4-tetrahydroquinolines via formal C-H, Ar-H coupling is described. In a new variant, copper(II) 2-ethylhexanoate has been identified as an inexpensive and efficient catalyst for this transformation, which utilises atmospheric oxygen as the re-oxidant.

AB - A copper(II)-catalysed approach to oxindoles, thio-oxindoles, 3,4-dihydro-1H-quinolin-2-ones, and 1,2,3,4-tetrahydroquinolines via formal C-H, Ar-H coupling is described. In a new variant, copper(II) 2-ethylhexanoate has been identified as an inexpensive and efficient catalyst for this transformation, which utilises atmospheric oxygen as the re-oxidant.

KW - Catalysis

KW - Copper

KW - Dihydroquinolinones

KW - Oxindoles

KW - Tetrahydroquinolines

UR - http://www.scopus.com/inward/record.url?scp=84911070252&partnerID=8YFLogxK

U2 - 10.1002/chem.201403917

DO - 10.1002/chem.201403917

M3 - Article

C2 - 25212595

SN - 1521-3765

VL - 20

SP - 14063

EP - 14073

JO - Chemistry : A European Journal (Weinheim an der Bergstrasse, Germany)

JF - Chemistry : A European Journal (Weinheim an der Bergstrasse, Germany)

IS - 43

ER -