A Health Services Research Agenda for Cellular, Molecular and Genomic Technologies in Cancer Care

Louise Wideroff; Kathryn A. Phillips; Gurvaneet Randhawa; Anita Ambs; Katrina Armstrong; Charles L. Bennett; Martin L. Brown; Molla S. Donaldson; Michele Follen; Sue J. Goldie; Robert A. Hiatt; Muin J. Khoury; Graham Stuart Lewis; Howard L. McLeod; Margaret Piper; Isaac Powell; Deborah Schrag; Kevin A. Schulman; Joan Scott

doi:10.1159/000203779

A Health Services Research Agenda for Cellular, Molecular and Genomic Technologies in Cancer Care

Louise Wideroff, Kathryn A. Phillips, Gurvaneet Randhawa, Anita Ambs, Katrina Armstrong, Charles L. Bennett, Martin L. Brown, Molla S. Donaldson, Michele Follen, Sue J. Goldie, Robert A. Hiatt, Muin J. Khoury, Graham Stuart Lewis, Howard L. McLeod, Margaret Piper, Isaac Powell, Deborah Schrag, Kevin A. Schulman, Joan Scott

Department of Sociology

Research output: Contribution to journal › Literature review › peer-review

Abstract

Background: In recent decades, extensive resources have been invested to develop cellular, molecular and genomic technologies with clinical applications that span the continuum of cancer care. Methods: In December 2006, the National Cancer Institute sponsored the first workshop to uniquely examine the state of health services research on cancer-related cellular, molecular and genomic technologies and identify challenges and priorities for expanding the evidence base on their effectiveness in routine care. Results: This article summarizes the workshop outcomes, which included development of a comprehensive research agenda that incorporates health and safety endpoints, utilization patterns, patient and provider preferences, quality of care and access, disparities, economics and decision modeling, trends in cancer outcomes, and health-related quality of life among target populations. Conclusions: Ultimately, the successful adoption of useful technologies will depend on understanding and influencing the patient, provider, health care system and societal factors that contribute to their uptake and effectiveness in 'real-world' settings. Copyright (C) 2009 S. Karger AG, Basel

Original language	English
Pages (from-to)	233-244
Number of pages	12
Journal	Public health genomics
Volume	12
Issue number	4
DOIs	https://doi.org/10.1159/000203779
Publication status	Published - Apr 2009

Keywords

Genomics
Health services research
Emerging technologies
Translational research
COST-EFFECTIVENESS ANALYSIS
METASTATIC BREAST-CANCER
REPORTS RADAR PROJECT
ADVERSE DRUG EVENTS
CLINICAL-PRACTICE
RACIAL-DIFFERENCES
CERVICAL-CANCER
PUBLIC-HEALTH
PROPHYLACTIC VACCINES
PROSTATE-CANCER

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Wideroff, L., Phillips, K. A., Randhawa, G., Ambs, A., Armstrong, K., Bennett, C. L., Brown, M. L., Donaldson, M. S., Follen, M., Goldie, S. J., Hiatt, R. A., Khoury, M. J., Lewis, G. S., McLeod, H. L., Piper, M., Powell, I., Schrag, D., Schulman, K. A., & Scott, J. (2009). A Health Services Research Agenda for Cellular, Molecular and Genomic Technologies in Cancer Care. Public health genomics, 12(4), 233-244. https://doi.org/10.1159/000203779

@article{5a2c2650c6f84910bcf59738a458497a,

title = "A Health Services Research Agenda for Cellular, Molecular and Genomic Technologies in Cancer Care",

abstract = "Background: In recent decades, extensive resources have been invested to develop cellular, molecular and genomic technologies with clinical applications that span the continuum of cancer care. Methods: In December 2006, the National Cancer Institute sponsored the first workshop to uniquely examine the state of health services research on cancer-related cellular, molecular and genomic technologies and identify challenges and priorities for expanding the evidence base on their effectiveness in routine care. Results: This article summarizes the workshop outcomes, which included development of a comprehensive research agenda that incorporates health and safety endpoints, utilization patterns, patient and provider preferences, quality of care and access, disparities, economics and decision modeling, trends in cancer outcomes, and health-related quality of life among target populations. Conclusions: Ultimately, the successful adoption of useful technologies will depend on understanding and influencing the patient, provider, health care system and societal factors that contribute to their uptake and effectiveness in 'real-world' settings. Copyright (C) 2009 S. Karger AG, Basel",

keywords = "Genomics, Health services research, Emerging technologies, Translational research, COST-EFFECTIVENESS ANALYSIS, METASTATIC BREAST-CANCER, REPORTS RADAR PROJECT, ADVERSE DRUG EVENTS, CLINICAL-PRACTICE, RACIAL-DIFFERENCES, CERVICAL-CANCER, PUBLIC-HEALTH, PROPHYLACTIC VACCINES, PROSTATE-CANCER",

author = "Louise Wideroff and Phillips, {Kathryn A.} and Gurvaneet Randhawa and Anita Ambs and Katrina Armstrong and Bennett, {Charles L.} and Brown, {Martin L.} and Donaldson, {Molla S.} and Michele Follen and Goldie, {Sue J.} and Hiatt, {Robert A.} and Khoury, {Muin J.} and Lewis, {Graham Stuart} and McLeod, {Howard L.} and Margaret Piper and Isaac Powell and Deborah Schrag and Schulman, {Kevin A.} and Joan Scott",

year = "2009",

month = apr,

doi = "10.1159/000203779",

language = "English",

volume = "12",

pages = "233--244",

journal = "Public health genomics",

issn = "1662-4246",

publisher = "S. Karger AG",

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Wideroff, L, Phillips, KA, Randhawa, G, Ambs, A, Armstrong, K, Bennett, CL, Brown, ML, Donaldson, MS, Follen, M, Goldie, SJ, Hiatt, RA, Khoury, MJ, Lewis, GS, McLeod, HL, Piper, M, Powell, I, Schrag, D, Schulman, KA & Scott, J 2009, 'A Health Services Research Agenda for Cellular, Molecular and Genomic Technologies in Cancer Care', Public health genomics, vol. 12, no. 4, pp. 233-244. https://doi.org/10.1159/000203779

TY - JOUR

T1 - A Health Services Research Agenda for Cellular, Molecular and Genomic Technologies in Cancer Care

AU - Wideroff, Louise

AU - Phillips, Kathryn A.

AU - Randhawa, Gurvaneet

AU - Ambs, Anita

AU - Armstrong, Katrina

AU - Bennett, Charles L.

AU - Brown, Martin L.

AU - Donaldson, Molla S.

AU - Follen, Michele

AU - Goldie, Sue J.

AU - Hiatt, Robert A.

AU - Khoury, Muin J.

AU - Lewis, Graham Stuart

AU - McLeod, Howard L.

AU - Piper, Margaret

AU - Powell, Isaac

AU - Schrag, Deborah

AU - Schulman, Kevin A.

AU - Scott, Joan

PY - 2009/4

Y1 - 2009/4

N2 - Background: In recent decades, extensive resources have been invested to develop cellular, molecular and genomic technologies with clinical applications that span the continuum of cancer care. Methods: In December 2006, the National Cancer Institute sponsored the first workshop to uniquely examine the state of health services research on cancer-related cellular, molecular and genomic technologies and identify challenges and priorities for expanding the evidence base on their effectiveness in routine care. Results: This article summarizes the workshop outcomes, which included development of a comprehensive research agenda that incorporates health and safety endpoints, utilization patterns, patient and provider preferences, quality of care and access, disparities, economics and decision modeling, trends in cancer outcomes, and health-related quality of life among target populations. Conclusions: Ultimately, the successful adoption of useful technologies will depend on understanding and influencing the patient, provider, health care system and societal factors that contribute to their uptake and effectiveness in 'real-world' settings. Copyright (C) 2009 S. Karger AG, Basel

AB - Background: In recent decades, extensive resources have been invested to develop cellular, molecular and genomic technologies with clinical applications that span the continuum of cancer care. Methods: In December 2006, the National Cancer Institute sponsored the first workshop to uniquely examine the state of health services research on cancer-related cellular, molecular and genomic technologies and identify challenges and priorities for expanding the evidence base on their effectiveness in routine care. Results: This article summarizes the workshop outcomes, which included development of a comprehensive research agenda that incorporates health and safety endpoints, utilization patterns, patient and provider preferences, quality of care and access, disparities, economics and decision modeling, trends in cancer outcomes, and health-related quality of life among target populations. Conclusions: Ultimately, the successful adoption of useful technologies will depend on understanding and influencing the patient, provider, health care system and societal factors that contribute to their uptake and effectiveness in 'real-world' settings. Copyright (C) 2009 S. Karger AG, Basel

KW - Genomics

KW - Health services research

KW - Emerging technologies

KW - Translational research

KW - COST-EFFECTIVENESS ANALYSIS

KW - METASTATIC BREAST-CANCER

KW - REPORTS RADAR PROJECT

KW - ADVERSE DRUG EVENTS

KW - CLINICAL-PRACTICE

KW - RACIAL-DIFFERENCES

KW - CERVICAL-CANCER

KW - PUBLIC-HEALTH

KW - PROPHYLACTIC VACCINES

KW - PROSTATE-CANCER

UR - http://www.scopus.com/inward/record.url?scp=67449086758&partnerID=8YFLogxK

U2 - 10.1159/000203779

DO - 10.1159/000203779

M3 - Literature review

SN - 1662-4246

VL - 12

SP - 233

EP - 244

JO - Public health genomics

JF - Public health genomics

IS - 4

ER -

A Health Services Research Agenda for Cellular, Molecular and Genomic Technologies in Cancer Care

Abstract

Keywords

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