By the same authors

From the same journal

A key role for iodobenzene in the direct C-H bond functionalisation of benzoxazoles using PhI(OAc) mediated by a Pd(OAc) /1,10-phenanthroline catalyst system: In situ formation of well-defined Pd nanoparticles

Research output: Contribution to journalArticlepeer-review

Published copy (DOI)



Publication details

JournalTetrahedron Letters
DatePublished - 5 Jun 2013
Issue number23
Pages (from-to)2906-2908
Original languageEnglish


PhI(OAc) has previously been reported as a reagent for the direct arylation of C-H bonds in benzoxazole in a Pd-mediated process. However, evidence reported here suggests this reagent degrades to iodobenzene under the literature reported reaction conditions. Further, we present evidence for the rapid formation of Pd nanoparticles in this reaction, leading us to question what is the active catalytic Pd phase in coupling chemistry?.

Discover related content

Find related publications, people, projects, datasets and more using interactive charts.

View graph of relations