A lack of experience-dependent plasticity after more than a decade of recovered sight

Elizabeth Huber; Jason M. Webster; Alyssa A. Brewer; Donald I. A. MacLeod; Brian A. Wandell; Geoffrey M. Boynton; Alex R. Wade; Ione Fine

doi:10.1177/0956797614563957

A lack of experience-dependent plasticity after more than a decade of recovered sight

Elizabeth Huber, Jason M. Webster, Alyssa A. Brewer, Donald I. A. MacLeod, Brian A. Wandell, Geoffrey M. Boynton, Alex R. Wade, Ione Fine

Psychology

Research output: Contribution to journal › Article › peer-review

Abstract

In 2000, monocular vision was restored to M. M., who had been blind between the ages of 3 and 46 years. Tests carried out over 2 years following the surgery revealed impairments of 3-D form, object, and face processing and an absence of object- and face-selective blood-oxygen-level-dependent responses in ventral visual cortex. In the present research, we reexamined M. M. to test for experience-dependent recovery of visual function. Behaviorally, M. M. remains impaired in 3-D form, object, and face processing. Accordingly, we found little to no evidence of the category-selective organization within ventral visual cortex typically associated with face, body, scene, or object processing. We did observe remarkably normal object selectivity within lateral occipital cortex, consistent with M. M.'s previously reported shape-discrimination performance. Together, these findings provide little evidence for recovery of high-level visual function after more than a decade of visual experience in adulthood.

Original language	English
Pages (from-to)	393-401
Number of pages	9
Journal	Psychological Science
Volume	26
Issue number	4
Early online date	3 Mar 2015
DOIs	https://doi.org/10.1177/0956797614563957
Publication status	Published - Apr 2015

Bibliographical note

Keywords

Neuroimaging
Vision
Face perception
Object recognition
Temporal lobe

Access to Document

10.1177/0956797614563957

Cite this

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title = "A lack of experience-dependent plasticity after more than a decade of recovered sight",

abstract = "In 2000, monocular vision was restored to M. M., who had been blind between the ages of 3 and 46 years. Tests carried out over 2 years following the surgery revealed impairments of 3-D form, object, and face processing and an absence of object- and face-selective blood-oxygen-level-dependent responses in ventral visual cortex. In the present research, we reexamined M. M. to test for experience-dependent recovery of visual function. Behaviorally, M. M. remains impaired in 3-D form, object, and face processing. Accordingly, we found little to no evidence of the category-selective organization within ventral visual cortex typically associated with face, body, scene, or object processing. We did observe remarkably normal object selectivity within lateral occipital cortex, consistent with M. M.'s previously reported shape-discrimination performance. Together, these findings provide little evidence for recovery of high-level visual function after more than a decade of visual experience in adulthood.",

keywords = "Neuroimaging, Vision, Face perception, Object recognition, Temporal lobe",

author = "Elizabeth Huber and Webster, {Jason M.} and Brewer, {Alyssa A.} and MacLeod, {Donald I. A.} and Wandell, {Brian A.} and Boynton, {Geoffrey M.} and Wade, {Alex R.} and Ione Fine",

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AU - Huber, Elizabeth

AU - Webster, Jason M.

AU - Brewer, Alyssa A.

AU - MacLeod, Donald I. A.

AU - Wandell, Brian A.

AU - Boynton, Geoffrey M.

AU - Wade, Alex R.

AU - Fine, Ione

N1 - © The Author(s) 2015.

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N2 - In 2000, monocular vision was restored to M. M., who had been blind between the ages of 3 and 46 years. Tests carried out over 2 years following the surgery revealed impairments of 3-D form, object, and face processing and an absence of object- and face-selective blood-oxygen-level-dependent responses in ventral visual cortex. In the present research, we reexamined M. M. to test for experience-dependent recovery of visual function. Behaviorally, M. M. remains impaired in 3-D form, object, and face processing. Accordingly, we found little to no evidence of the category-selective organization within ventral visual cortex typically associated with face, body, scene, or object processing. We did observe remarkably normal object selectivity within lateral occipital cortex, consistent with M. M.'s previously reported shape-discrimination performance. Together, these findings provide little evidence for recovery of high-level visual function after more than a decade of visual experience in adulthood.

AB - In 2000, monocular vision was restored to M. M., who had been blind between the ages of 3 and 46 years. Tests carried out over 2 years following the surgery revealed impairments of 3-D form, object, and face processing and an absence of object- and face-selective blood-oxygen-level-dependent responses in ventral visual cortex. In the present research, we reexamined M. M. to test for experience-dependent recovery of visual function. Behaviorally, M. M. remains impaired in 3-D form, object, and face processing. Accordingly, we found little to no evidence of the category-selective organization within ventral visual cortex typically associated with face, body, scene, or object processing. We did observe remarkably normal object selectivity within lateral occipital cortex, consistent with M. M.'s previously reported shape-discrimination performance. Together, these findings provide little evidence for recovery of high-level visual function after more than a decade of visual experience in adulthood.

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KW - Face perception

KW - Object recognition

KW - Temporal lobe

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